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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Effect of surfactants on the Acid catalyzed hydrolysis of aliphatic esters having variation in chain length of their alkyl part

Asok K. Jana*1, D. Vijayasarathi1 and Papiya Jana2 1Department of Chemistry, Kanchi Mamunivar Centre for Post Graduate Studies, Pondicherry – 605 008, India. 2Departments of Chemistry, Sri Manakula Vinayagar Engineering College, Pondicherry -605107, India  A B S T R A C T The kinetics of acidic hydrolysis of simple aliphatic esters in aqueous and surfactant media has been studied. Different ... Read More »

Green Synthesis of Zinc Nanoparticles using Punica granatum Fruit Extract and their Structural and Optical Properties

R. Rajakumari*1, 1S. Kalaiarasi, 2L.Parimala 1PG and Research Department of Physics, Queen Mary’s College (Autonomous), Chennai, Tamil Nadu, India 2Annai Violet College of Arts & Science, Chennai, Tamil Nadu, India A B S T R A C T The Zinc nanoparticles were prepared with the fruit extract of Punica granatum via green synthesis. Though physical and chemical methods are more ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Darunavir and Cobicistat by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Sd. Asra Ayesha*, G. Devika Subramaniyan Bomma Institute of Pharmacy, Allipuram, Khammam, Telangana, India A B S T R A C T A new, simple, precise, accurate and reproducible RP-HPLC method for simultaneous estimation of Darunavir and Cobicistat in bulk and pharmaceutical formulations was developed. Separation of Darunavir and Cobicistat was successfully achieved on C18 ODS(250mm x 4.6 mm), 5µm., ... Read More »

Analytical Method Development and Validation for the Estimation of Erlotinib Hydrochloride by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Gobala Krishnan P*, Munisekhar V, Ranjit Singh B. Rathore Department of Pharmaceutical Chemistry, Vagdevi college of Pharmacy & Research centre, Nellore, Andhra Pradesh, India. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Erlotinib hydrochloride by using the HPLC method for Erlotinib hydrochloride as per ICH Guide lines. Shimadzu LC-2010 series ... Read More »

Simultaneous Estimation Method for the Determination of Rosuvastatin and Ezetimibe from their Combination Tablet Dosage form Using RP-HPLC

S. Mehboob Basha, Shaik Mohmmed Yusuf*, Vummadi Sai Chandana, Bumireddy Pavani, E. Vijay Kumar Department of Pharmaceutical Analysis, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, YSR Kadapa, A.P. India A B S T R A C T Rosuvastatin is an HMG Co-A inhibitor and Ezetimibe is an intestinal cholesterol absorption inhibitor. The combination formulation is used for the treatment of hypercholestrolemia. A ... Read More »

Validated RP-HPLC Method for Simultaneous Estimation of Metformin and Vildagliptin in Its Tablets

Karem Kishore Kumar Reddy, Shaik Mohammed Yusuf*, E. Vijay Kumar, Bumireddy Pavani, E. Divya, Vummadi Sai Chandana Department of Pharmaceutical Analysis, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, YSR Kadapa, A.P. India A B S T R A C T A simple, rapid, sensitive and robust reversed phase-HPLC method was developed and validated to measure simultaneously the amount of Metformin and Vildagliptin ... Read More »

A Review on Newer Trends in Treatment for Diabetes Management in Health Care Practice

A. Bharath kumar1*, S.P. Zakiullah1, B. Kumar1, Sk. Kareemulla1, Ramesh Dhani2 1Department of Pharmacy Practice, Annamcharya college of Pharmacy, Rajampet, A.P, India-518218 2Department of Pharmaceutical Chemistry, Ratnam Institute of Pharmacy, Nellore, A.P, India-524346. A B S T R A C T It is a group of metabolic diseases in which there is high blood sugar levels over a prolonged period. ... Read More »

Anti-Diabetic Effect of Diospyros Malabarica against Alloxan Induced Diabetes in Rats

A. Ravi Kumar1*, P. Vengalrao1, S. Satyanarayana1, Gireesh Jampana1, Matle Naga Priyanka2 1Celon Laboratories Private Limited, Aleap Industrial Estate, Gajularamaram, R.R. Dist., Telgana-500090 2Department of Pharmaceutical Analysis Narayana Pharmacy College, Nellore, Andhra Pradesh, India A B S T R A C T The Present study was under taken to evaluation of anti-diabetic potential of Diospyros malabarica(DM) leaves in low dose ... Read More »

Development and Validation of RP-HPLC Method for the Estimation of Sitagliptin Phosphate in Bulk and Its Tablet Dosage Form

I. Arulraj1, P. Vembu2 and A. Chenthilnathan1* 1Department of Pharmaceutical Chemistry, Manonmaniam Sundaranar University, Tirunelveli – 627 012, Tamil Nadu, India. 2Bafna Pharmaceuticals Limited, Grantlyon village, Chennai – 600 052, Tamil Nadu, India. A B S T R A C T A simple and sensitive reversed-phase liquid chromatographic method has been developed and validated for the estimation of Sitagliptin phosphate ... Read More »

Antibacterial Activity of Various Extract of Mucuna Pruriens Linn. Seeds

Sushma Jhariya*, Arun kakkar and Manoj Kumar Pathak Natural product Laboratory, Department of Chemistry, Govt. Model Science College, South Civil Lines, Jabalpur,  M.P, India–482001. A B S T R A C T Antibacterial activity of different extract of seeds of Mucuna pruriens was examined. The antibacterial activity of different extract of each of 50 mg/ml concentrations was determined by disc ... Read More »

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