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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Identification of Steroids in Different Ayurvedic Formulations Available in Local Market

M. Siddalingeswara, G. Kavya, K. Nandini, K. Sumala, Naresh Gorantla* Department of Pharmaceutics, Balaji College of pharmacy, Ananthapuramu, Andhra Pradesh, India. A B S T R A C T Ayurveda, the science of life is an ancient system of medicine sprouted out in India. The basic formulations in Ayurveda are the Herbomineral preparations like Bhasmas, churnas, lehas, asavas, arishtas etc., ... Read More »

Synthesis of Chiral 3-[[(Aryl) methyl] amino]- and 3-[[(Heteroaryl)-methyl]-amino]-quinuclidines with High Biological Activity against Intracellular Trypansoma cruzi Amastigotes

Bruna Fereira de Souza1, Mayara Roncaglia dos Santos1, Renan Pimentel de Souza1, Simon Bernhard Cämmerer1*, Natália Aimée d´Angelo2, Caio Haddad Franco3, Carolina Borsoi Moraes3 Lúcio H. Freitas-Junior3* 1Instituto de Química, Universidade Estadual de Campinas, Rua Monteiro Lobato S/N, Cidade Universitaria Zeferino Vaz, Barão Geraldo, CP 6154, CEP 13083-970, Campinas, São Paulo, Brasil. 2Instituto de Ciências da Saúde – ICS, Universidade ... Read More »

Physico-Chemical and Thermo gravimetric Analysis of Rubidium Soaps in Solid State

Saroha Satya Pal Saroha*1, Mehrotra Krishna N2 and 3Ganjewala Deepak 1Department of Chemistry, Amity Institute of Biotechnology, Amity University, Sector125 Noida, Uttar Pradesh., India 2University of Jodhpur, Jodhpur, Rajasthan, India 3Department of Plant & Environmental Biotechnology, Amity Institute of Biotechnology, Amity University, Noida, U.P, India A B S T R A C T Rubidium soaps (Caprylate, Myristate and Pamitate) were ... Read More »

Antidiabetic Activities of Ipomoea sepiaria (Koenig Ex. Roxb) Ethanolic Leaves Extracts in Streptozotocin Induced Diabetic Rats

Senthil.J1*, Rameashkannan M.V1, Mani.P2, Jayaseelan.T3, Dinesh Kumar.G3  1Department of Medicinal Plant Biotechnology, Sharmila Institute of Medicinal Products Research Academy, Thanjavur, Tamilnadu, India. 2Department of Biotechnology, Annai College of Arts and Science, Kumbakonam, Tamilnadu, India. 3P.G and Research Development of Zoology and Biotechnology, A.V.V.M. Sri Pushpam College, Poondi,Thanjavur, Tamilnadu, India. A B S T R A C T Diabetes mellitus (DM) is ... Read More »

Phytochemical screening and quantitative analysis of bioactive components in various extracts of Alternanthera sessilis linn Leaves

Lalitha Sree T*1 and Dr. K. Vijayalakshmi2 1Research Scholar, Department of Biochemistry, Bharathi Women’s College, Chennai–600108, Tamil Nadu, India. 2Associate Professor, Department of Biochemistry, Bharathi Women’s College, Chennai-600108, Tamil Nadu, India. A B S T R A C T The plant kingdom is a treasure house of structurally diverse phytochemical compounds. The green vegetable Alternanthera sessilis is used in medicine ... Read More »

Preventive Effect of Premna Latifolia against High Fructose Diet Induced Insulin Resistance, Hyperlipidemia and Obesity in Male Wister Rats

Gampa Vijaya Kumar*1, K. Ramprasad2 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Keesara,Rangareddy, Telangana, India. 2Department of Pharmacology, Sree Chaitanya Institute of Pharmaceutical Sciences, L.M.D Colony, Thimmapur, Karimnagar, Telangana, India. A B S T R A C T The aim of this study was to investigate ant diabetic effect of premna latifolia on the ... Read More »

Synthesis, Characterisation and Biological Evaluation of Novel BIS 1,3,4-Thiadiazole ring containing Indole and pyridine Moieties

V. Prabhakar*1, K. Sudhakar Babu1, L.K. Ravindranath1, J. Latha2 1Department of Chemistry, Sri Krishnadevaraya University, Anantapuramu, A P, India. 2Department of Bio-technology, Sri Krishnadevaraya University College of Engineering & Technology, S.K. University, Anantapuramu – 515003 (A.P) India A B S T R A C T The article is aimed to synthesize, characterize and screening the biological activity of 2-(5-(1H-indole-2-yl)-1, 3, ... Read More »

Spectrophotometric Determination of Moxifloxacin Hydrochloride using Palladium (Pd-II) ions in micellar medium

Madhuri.D1*, Chandrasekhar K.B2, Devanna N3, Somasekhar G4 1Department of Pharmaceutical Analysis, Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, A. P, India 2Director & Professor, OTPRI-JNTUA, Anantapur, A.P, India-515002 3Professor, Department of Chemistry, JNT University, Anantapur A.P, India-515002 4Department of Pharmaceutical Chemistry, Safa College of Pharmacy. Kurnool, A.P, India A B S T R A C T A simple ,sensitive ... Read More »

Synthesis and Characterization of Zn-Al-Cl of Hydrotalcites and their Application in Four Component Synthesis of 4H-Pyrano[2,3C] Pyrazoles

Jugraj Jatav*, Ruchi Gupta, Santosh Kumar Bhardwaj Department of Chemistry, Jiwaji University, 474011 Gwalior, M.P. India A B S T R A C T Zn/Al hydrotalcite acts as an efficient heterogeneous basic catalyst for the synthesis of 4H-pyrano[2,3-c] pyrazoles via a multi-component reaction of  hydrazine hydrate, ethyl acetoacetate, aldehydes, and malononitrile in ethanol at ambient temperature. The hydrotalcite catalyst was ... Read More »

Analytical Method Development and Validation for the Estimation of Efavirenz by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Gobala Krishnan P*1, Munisekhar V, Ranjit Singh B. Rathore Department of Pharmaceutical Chemistry, Vagdevi college of Pharmacy & Research centre, Nellore, Andhra Pradesh, India. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Efavirenz  by using KromosilColumn (100-5 C18.60×4.6mm), flow rate was 1ml/min, mobile phase ratio was Acetonitril: Phosphate buffer PH ... Read More »

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