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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Design and Characterization of Chronotherapeutic Drug Delivery System of Dexibuprofen for the Treatment of Arthritis

Kishor*1, Bindu Madhavi2, K. Someshwar2 1Department of Pharmceutics, St. Pauls College of Pharmacy, Hyderabad, Telangana, India 2Manager, Formulation R&D, KP Labs (A Division of KDPL), Kothapet, Hyderabad Telangana, India A B S T R A C T In the present research work, chronotherapeutic drug delivery of Dexibuprofen was carried out. Chronotherapeutics refers to a treatment method in which in-vivo drug ... Read More »

Formulation Development and In -Vitro Evaluation of Bilayer Tablets Containing Dimenhydrinate and Cinnarizine

Kiran Kumar Yada1*, Dharmajit Pattanayak1, Saumya Das1, Vagdevi Y2 1Associate Professor, Vikas college of pharmaceutical sciences, Rayanigudem, Suryapet. 2Research Assistant, KP Labs, Kothapet (A Division of KDPL), Hyderabad. A B S T R A C T The conclusions  arrived  in  this  thesis  indicated  that  the  formulations  of Dimenhydrinate sustained in  this  investigation  was  found  to  be  satisfactory  based  on  in-vitro  release  ... Read More »

A Review on Thyroid Disease

B. Kumar*, K. Durga Prasanna Roja,  M. Gobinath Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Pidthapolur, Nellore. A B S T R A C T The thyroid gland is one of the largest endocrine gland and consists of two connected lobes. The thyroid gland is found in the neck, below the thyroid cartilage. It participates in these processes by producing thyroid hormones, the principal ones ... Read More »

Development and Validation of New UV Spectroscopic and HPLC Methods for the Estimation of Zidovudine in Bulk and Pharmaceutical Dosage Form

Telugu Naga Mohan, Shaik Mohammed Yusuf*, Seerla Eswaraiah, D. Chinna Raju, E. Vijay Kumar Srinivasa Institute of Pharmaceutical sciences, Proddatur, YSR Kadapa [Dist]. AP. India.  A B S T R A C T In the present work, two simple, sensitive and specific methods (UV Spectroscopy and RP-HPLC) have been developed for the quantitative estimation of Zidovudine in bulk and pharmaceutical ... Read More »

Simultaneous Estimation Amitriptyline Hydrochloride and Chlordiazepoxide by HPLC Method

Seerla Eswaraiah, Shaik Mohammed Yusuf*, T. Naga Mohan, D. Chinna Raju, E. Vijay Kumar Srinivasa Institute of Pharmaceutical Sciences, Proddatur, YSR Kadapa, A.P. India A B S T R A C T A simple, economic, selective, precise, and accurate Reverse Phase High Performance Liquid Chromatography method for analysis of Amitriptyline HCl & Chlordiazepoxide in tablet dosage form was developed and ... Read More »

Method Development and Validation by RP-HPLC for the Simultaneous Estimation of Cinacalcet and Maxacalcitol in Tablet Dosage Form

N. Usha*, M. Gobinath, V. Hari Baskar, Ramesh Dhani, A. Soniya Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India.  A B S T R A C T A Simple, selective, accurate, precise and linear RP-HPLC method was developed subsequently validated for estimation of cinacalcet in bulk & tablet dosage form. Gradient elution at a ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Telmisartan and Hydrochlorothiazide by UV-Spectrophotometric Method in Bulk and Tablet Dosage Form

L. Kanaka Lakshmi*, S. Harshini, Dr. Vasudha Bakshi, D. Sireesha, Akiful Haque Deparment of Pharmaceutical Analysis, School of Pharmacy, Anurag Group of Institutions, Ghatkesar, Ranga Reddy, Telangana-501301, India.  A B S T R A C T The Spectroscopic method was successfully developed for the separation of Hydrochlorothiazide and Telmisartan by using as solvent methanol, detection wavelength were at 271nm and ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Telmisartan and Hydrochlorothiazide by RP-HPLC Method in Bulk and Tablet Dosage Form

L. Kanaka Lakshmi*, S. Harshini, Dr. Vasudha Bakshi, D. Sireesha, Akiful Haque Deparment of Pharmaceutical Analysis, School of Pharmacy, Anurag Group of Institutions, Ghatkesar, Ranga Reddy, Telangana-501301, India.  A B S T R A C T The chromatographic conditions were successfully developed for the separation of Hydrochlorothiazide and Telmisartan by using Agilent C18 column (4.6×150mm)5µ, flow rate was 1ml/min, mobile ... Read More »

Analytical Method Development and Validation by RP-HPLC for Simultaneous Estimation of Ketorolac and Febuxostat in Combined Tablet Dosage Form

Gampa Vijaya Kumar*1, Dr. P. Shashikala2 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Keesara, Rangareddy, Telangana, India 2Professor, Department of Pharmaceuticals and fine Chemicals, University College of Technology, Osmania University, Hyderabad, Telangana, India.  A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the ... Read More »

Zinc Oxide Nanoparticles for Choosy Disastrous of Tumor Cells and Potential for Medicine Freighting Uses

Kiran Mishra* Applied Sciences Department, Chandigarh Engineering College, Landran, Mohali, Punjab, India A B S T R A C T Nanotechnology speaks to another and empowering stage that guarantees to give an expansive scope of novel uses and enhanced advances for organic and biomedical applications. This ultra-little size is practically identical to actually happening proteins and biomolecules in the phone ... Read More »

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