Conceptual Study on Creutzfeldt Jakob Disease

S. Shereen Sulthana*, N. Pavan Kumar¹, S. Chakravarthi², S. Chandini³, J. Sai Maneesha⁴
*¹²³⁴Student, Vasavi Institute of Pharmaceutical and Sciences, Peddapalli, Kadapa. A.P

A. J. Med. Pharm, Sci., 2024, 12(1): 16-18
DOI: https://doi.org/10.30904/j.ijctpr.2024.4624

A B S T R A C T
Creutzfeldt Jakob Disease belongs to the family of human prion diseases. It is a rapidly progressive rare transmissible universal fatal degenerative condition caused by prion proteins it occurs when the normal PrP proteins get converted into abnormal proteins (PrPsc). One person in one million populations is affected by the consumption of infectious cattle meat. There are three types of Creutzfeldt-Jakob disease. This disease mostly affects elderly patients aged between 50-70 years. The diagnosis criteria include Electroencephalogram (EEG), Magnetic Resonance Imaging (MRI), and Biomarkers in CSF but Creutzfeldt-Jakob disease is confirmed by Biopsy.
Keywords: Magnetic Resonance Imaging (MRI), Electroencephalogram (EEG), Creutzfeldt-Jakob disease