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Sushma Jhariya*, Arun kakkar and Manoj Kumar Pathak Natural product Laboratory, Department of Chemistry, Govt. Model Science College, South Civil Lines, Jabalpur, M.P, India–482001. A B S T R A C T Antibacterial activity of different extract of seeds of Mucuna pruriens was examined. The antibacterial activity of different extract of each of 50 mg/ml concentrations was determined by disc ... Read More »
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Category Archives: Chemical Sciences and Chemical research
A Review on Phytochemistry and Phytopharmaclogy of Cajanus cajan (L) Millsp for the future Challenges and Perspective
B. Vanitha*1, B. Durai Swamy2, P. Dhamodaran3, G. Neelamma1 1Research Scholar, Department of Pharmacognosy and Phytopharmacy, JSS College of Pharmacy, Ooty-643001, Tamil Nadu, India 2Head of Department, Department of Pharmacognosy and Phytopharmacy, JSS College of Pharmacy, Ooty–643001, Tamil Nadu, India 3Professor, Department of Pharmacognosy and Phytopharmacy, JSS College of Pharmacy, Ooty-643001犀利士 , Tamil Nadu, India A B S T R A C ... Read More »
Synthesis and Spectral Characterization of Some 1,3,5-Dithazines with Chalcone Backbone
Dipak T. Tayade*1, Siddharth A. Waghmare2 1Dept. of Chemistry, Govt. Vidarbha Institute of Science & Humanities, Amravati-444 604, M.S, India 2Dept. of Chemistry, Ghulam樂威壯 Nabi Azad College, Barshitakli, Akola-444 404, MS, India. A B S T R A C T Recently, a series of (2E)-1-{4-[2-(prop-2-en-1-yl)-4-substitutedimino-1,3,5-dithiazino-6-yl]aminophenyl}-3-(3,4-dimethoxy phenyl) prop-2-en-1-one (IIIa-e) had been synthesized by refluxing (2E)-1-[4-(5-(2-methylpropan-2-yl)-2,4-dithiobiureto) phenyl]-3-(3,4-dimethoxy phenyl) prop-2-en-1-one (I) with alkyl/aryl ... Read More »
Analytical Method Development and Validation for the Simultaneous Estimation of Candesartan cilexitil and Hydrochlorothiazide by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form
Idavalapati Chandana*, M. Gobinath, V. Haribaskar, Ramesh Dhani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, Andhra Pradesh, India A B S T R A C T The chromatographic conditions were successfully developed for the separation of Candesartan cilexitil and Hydrochlorothiazide by using zodiac sil C18 Column (150mm x 4.6mm)5µm, flow rate was 1ml/min, mobile phase ratio was ... Read More »
Studies on a New Schiff Baselig and H3 (pte-tsc) synthesized by condensing 7–Acetonyl–xanthopterin [H2 (pte)] with thiosemicarbazide [H(TSC)] and its molybdenum complexes exhibiting reactivity towards Me3N→O, PyN→O and PPh3; crystal structure of 2–pivaloylamino–7–acetonyl–xanthopterin – water (1/1).
Md Afsar Alia and Parag S Royb* aAcharya Jagadish Chandra Bose College, 1/1B, A.J.C. Bose Road, Kolkata – 700020. bDepartment of Chemistry, University of North Bengal, Dist. Darjeeling 734 013, India A B S T R A C T A new Schiff base ligand,H3 (pte-tsc) was synthesized by the condensation of 7-acetonyl-xanthopterin [H2(pte)] and thiosemicarbazide [H(tsc)]. The pterin starting material ... Read More »
Inslico-Prediction of Drug Solubility in Aquous Media by Theoritical Descriptors and QSAR Method
Elham Baher*, Poneh Ebrahimi, and Naser Darzi Naftchali Faculty of science, Department of Chemistry, Golestan University, Gorgan, Iran. A B S T R A C T The most key factor in transition of drugs across the biological membrane is their solubility in water. In this study, a novel theoretical model was proposed for the prediction of drug solubility in the ... Read More »
Synthesis and Evaluation of Some Substituted New Pyrazoline Derivatives of Biological Interest
Amol S Dighe* Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni, Maharashtra, India. A B S T R A C T The synthesis, structure and biological activity of Pyrazoline derivatives have long been the focus of research interests in the field of Medicinal Chemistry. A number of Pyrazoline derivatives have been reported to possess interesting biological activities ... Read More »
Development and Validation of a Stability Indicating RP-HPLC Method for the Determination of Piroxicam in Pharmaceutical Dosage Form
A. Chandra Prabha1, M. Sankar2 and A. Chenthilnathan1* 1Department of Pharmaceutical Chemistry, Manonmaniam Sundaranar University, Tirunelveli–627012, Tamil Nadu, India. 2Caplin Point Laboratories Ltd., Gummidipoondi, Chennai–601201, Tamil Nadu, India A B S T R A C T A stability-indicating RP-HPLC was developed and validated for the determination of Piroxicam in bulk and its injection dosage form. The separation was carried out ... Read More »
Development and Validation of a New RP-HPLC method for the simultaneous estimation of Sulfamethoxazole sodium and Trimethoprim in finished tablet dosage form
K. Satish*1, V. Karthik Varma2, A. Sunil Kumar3, Kranthi Ponugoti4, J. Karthik5 1,2, 3Department of Pharmaceutical Analysis and Quality Assurance, Vikas College of Pharmaceutical Sciences, Rayanigudem, Suryapet-508376, Telangana, India. 4Department of Pharmacology, Malla Reddy College of Pharmacy, Kompally, Hyderabad-500043, India. 5Department of Pharmceutical Chemistry, Madhira Institute of Technology and Sciences, Madhira Nagar, Chilkur, Nalgonda, Kodad-508206, Telangana, India. A B S T ... Read More »
Phytochemical Investigation and Antidepressant Activity of Coccinia Grandis
A. Hima Bindu, M. Navaneetha, K. Prasad, K. Triveni, S. Ramakrishna, B. Nagendra Babu, Naresh Gorantla* Department of Pharmaceutics, Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India. A B S T R A C T In this present work systemic phytochemical investigation of Coccinia grandis work done and it is also evaluated for antidepressant activity by the aqueous extract of ... Read More »
