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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Synthesis and Characterization of 1-Phenyl-3-[4-(2-p-Cl-phenylimino-4-substitutedimino-1, 3, 5-dithiazino) amino phenyl]-prop-2-ene-1-ones

Dipak T. Tayade1*, Sanghapal S. Padhen2 1Dept. of Chemistry, Govt. Vidarbha Institute of Science & Humanities, Amravati-444 604, (MS), India 2Dept. of Chemistry, Rajarshee Shahu Science College, Chandur Rly Dist Amravati-444904, (MS), India. A B S T R A C T Recently in this laboratory series of 1-phenyl-3-[4-(2-p-Cl-phenylimino-4-substituted imino-1,3,5-dithiazino)-amino phenyl]-prop-2-ene-1-ones (VIIIea-ee) had been synthesized by the interaction of  1-phenyl-3-[4-(5-p-Cl-phenyl-2,4-dithiobiureto) phenyl]-Prop-2-ene-1-ones ... Read More »

Degradation Impurities in Linagliptin Drug Product

Naresh Akkinaa, Bala Narasimha Reddy Gonaa,B. Venkateswara Raob, Paul Douglas Sanasib, Sukumar Nandi*a aDepartment of Chemical Research and Development, Aurobindo Pharma limited., Survey No. 71 & 72, Indrakaran Village, Sangareddy Mandal, Medak District – 502 329, Telangana, India. bDepartment of Engineering Chemistry, A.U. College of Engineering, Andhra University, Visakhapatnam-530003, Andhra Pradesh, India. A B S T R A C T ... Read More »

Studies on the molecular interaction of Azure dyes with sodium lauryl sulphate

Papiya Jana1, T. Salina2 and Asok K. Jana2* 1Department of Chemistry, Sri Manakula Vinayagar Engineering College, Pondicherry 605 107, India 2Department of Chemistry, Kanchi Mamunivar Centre for Post-Graduate Studies, Pondicherry 605 008, India  A B S T R A C T The absorption spectra of Azure dyes such as Azure A, Azure B and Azure C in aqueous solution of ... Read More »

Synthesis and Anti-Bacterial Activity of Novel Azetidinone Containing Quinoline Derivatives

Mahaboob Basha G*, Pramod. N, Dwarakanadha Reddy P, Swarnalatha D, Nirmala Devi. B, Sarovar Reddy.V Annamacharya College of Pharmacy, Rajampet-516126, Andhra Pradesh, India A B S T R A C T The ultrasonic velocity (u), density (ρ) and viscosity (η) of L-Valine solutions (0.02-0.12 mol.dm-3) in 2% of NaI solutions have been investigated at 288.15, 293.15, 298.15 and 303.15K respectively. ... Read More »

Synthesis and Screening of Anti-inflammatory activity of Coumarins bearing oxy acetic acid moiety

S. A. Tamboli1*, Dr. B. Y. Mane2 1Department of Pharmaceutical Chemistry, Padamshree Dr. Vittalrrao Vikhe Patil Foundation’s College of Pharmacy, Ahmednagar, Maharashtra, India-414 111. 2Asst. prof., Department of Pharmaceutical Chemistry and PG studies, Padamshree Dr. Vittalrrao Vikhe Patil Foundation’s College of Pharmacy, Ahmednagar, Maharashtra, India-414 111. A B S T R A C T Coumarins and its derivatives are considered ... Read More »

Ferric chloride immobilized on neutral alumina: an efficient catalyst for the solvent-free selective synthesis of 1, 2-disubstituted benzimidazoles

M. Hari Krishna, P. Thriveni* Department of Chemistry, Vikrama Simhapuri University, Nellore-524003, Andhra Pradesh, India. A B S T R A C T Synthesis of 1,2-disubstituted benzimidazoles from o-phenylenediamine and aromatic aldehydes in an excellent yield (86-95%)in presence of FeCl3–Al2O3 using microwave (MW) irradiation under solvent-free conditions. The present protocol shows some specific advantages such as mildness, short reaction times ... Read More »

Green Synthesis of Silver Nanoparticles: A Review

Prabhakara Rao Dasari*, Prashant Anthony Department of Chemistry, Sam Higginbottom Institute of Agriculture, Technology & Sciences, Allahabad-21100, India A B S T R A C T In the present years, nanotechnology is emerging as a favourite field for research. The nanoparticles have drawn the interest of the researchers from varied fields. These particles find different applications in diverse fields. The ... Read More »

Synthesis and Antimicrobial Evaluation of Some Novel Chalcones and Pyrazoles from Cyclic Imides under microwave irradiation

Prashant P. Chaudhari1 and Shankarsing S. Rajput2* 1DepartmentofChemistry, J.J.T. University, Jhunjhunu, Rajasthan, India 2DepartmentofChemistry, SVS’s Dadasaheb Rawal College, Dondaicha, Maharashtra, India A B S T R A C T A novel class of chalcones and pyrazoles has been prepared by using neutral alumina; under microwave activation and solvent free reaction condition. The compounds were screened for antimicrobial activity against bacterial ... Read More »

Determination of Febuxostat by Complexation with Mercury (Hg II) Ions Using Spectrophotometry

G. Somasekhar*, P. Mamatha, S. Nirosha rani, N. Raja Kumar, S. Ismail Zabiullah, M. Mahaboob Basha Department of Pharmaceutical Chemistry, Safa College of pharmacy, Dupadu, Kurnool, A.P. India A B S T R A C T A simple, sensitive and accurate Colorimetric method was described for the determination of Febuxostat (FBX) an antigout drug. The method is based on yellow coloured ... Read More »

Synthesis and Characterization of 5-Substituted Derivatives of 2, 4-Dithio-3-phenyl-6-chalcone-1,3,5-Triazines

Siddharth A. Waghmare1*, Dipak T. Tayade2 1Department of Chemistry, Ghulam Nabi Azad College, Arshitakli, Dist. Akola-444 404 (MS) India. 2Department if Chemistry, Govt. Vidarbha Institute of Science & Humanities, Amravati-444 604(MS) India A B S T R A C T Present research work involves, Synthesis of novel series of (2E)-1-[4-(2,4-dithio-3-phenyl-5-substituted-1,3,5-triazino-6-yl)aminophenyl]-3-(3,4-dimethoxyphenyl)prop-2-en-1-one (IIa-e) by the isomerisation of series of (2E)-1-[4-(2-phenylimino-4-substitutedimino)amino-1,3,5-dithiazino-6-yl)aminophenyl]-3-(3,4-dimethoxyphenyl)prop-2-en-1-one (Ia-e) under ... Read More »

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