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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Chemical and Mechanical Influence on Super molecular Structure of Cellulose

Michaela Filipi*, Miloslav Milichovsky  Department of Wood, Pulp a Paper, University of Pardubice, 532 10 Pardubice, Czech Republic Abstract The both chemical and mechanical influences on super molecular structure of cellulose represented by oxidative-hydrolysis process of oxycellulose preparation and beating of bleached linters, were studied by the use of X-ray computed microtomography methods. In order to elucidate a role of ... Read More »

Development and Validation of UFLC Method for the Determination of Docetaxel in Rat Plasma and Its Application in Pharmacokinetic Interaction with Diclofenac Sodium

Srikanth ReddyThummalapelly1, Mounika Arrabelli2, Raghuram Reddy Adidala*1 1Sri Shivani College of Pharmacy, Mulugu road, Warangal, A.P, India. 2Synapse Life Sciences, Nakkalagutta, Hanamkonda, Warangal, A.P, India. Abstract In cancer, the taxane of choice has historically been paclitaxel however, there is no substantial evidence that docetaxel  may be the preferred taxane in this disease. Docetaxel has many preclinical advantages over paclitaxel and ... Read More »

Effect of methanolic extract of Arbutus Pavarii Leaves as an antioxidant in the treatment of hypercholesterolemia in albino rats

Maraia F. Elmhdwi, Salem, G. El tumi  Department of Chemistry ( Biochemistry) , Faculty of  Science, Benghazi Univ., Libya Abstract The aim of this study was to investigate the antioxidant activity and  hypocholesterolemic effect of methanolic extract of Arbutus pavarii leaves (MEAPL). The hypercholesterolemia induced by cholesterol and cholic acid at 3:1 ratio in male albino rats. It was administered ... Read More »

Synthesis, spectral characterization and antioxidant activities of 2′, 6′-diphenyl-1, 3- dihydrospiro [benzo[d] imidazole-2,4′-piperidine]

Elanchezhian Balachandravinayagam*, Manivannan Natarajan and Selvanathan Ganesan Department of Chemistry, A.V.C. College (Autonomous), Mannampandal, Mayiladuthurai, Tamilnadu, India-609305 Abstract 2′,6′-diphenyl-1,3-dihydrospiro[benzo [d] imidazole-2,4′-piperidine] was synthesized by condensing  2,6-diarylpiperidin-4-one with o-phenylene diamine. The synthesized compound was characterized by IR, Mass and NMR spectral studies. NMR spectral assignments are made unambiguously by their one-dimensional (1H and 13C NMR) and two-dimensional (1H–1H COSY and NOESY) NMR ... Read More »

Kinetics of Adsorption of Methylene Blue onto Microwave Assisted Zinc Chloride Activated Carbon Prepared from Delonix regia pods

K. Ramesh1, A. Rajappa2 and V. Nandhakumar3*  1Department of Chemistry, Arasu Engineering College, Kumbakonam-612 501, India. 2Department of Chemistry, Sri Manakula Vinayagar Engineering College, Pondicherry–605 107, India. 3Department of Chemistry, A.V.V.M Sri Pushpam College, Poondi – 613 501, India. Abstract The activated carbon from Delonix regia (Flame tree) pods was prepared using orthogonal array experimental design method with the parameters ... Read More »

Multicomponent Synthesis of β-Acetamidoketones by using mix metal oxide CuO-SnO2 as Versatile Catalyst

1Deepak. M. Nagrik*, 2Shrikant S. Patil, 2Rameshwar S. Dhamak  1Department of Chemistry, G.S. College, Khamgaon, M.S., India-444303 2Department of Chemical Technology SGB Amravati University, Amravati, M.S., India-444602 Abstract Multicomponent reactions (MCRs) are emerged as one of the most imperative synthesis route in organic synthesis due to their wide application range in pharmaceutical chemistry. A variety of β-acetamido ketones were readily ... Read More »

Synthesis and Antifungal Properties of Some Nitroimidazole Derivatives

Justyna Żwawiak1*, Waldemar Perdoch2, Bartłomiej Mazela2, Lucjusz Zaprutko1  1Dept. of Organic Chemistry, Pharmaceutical Faculty, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland 2Institute of Chemical Wood Technology, Poznan University of Life Sciences, Wojska Polskiego 28, 60-637, Poznań, Poland Received: 21 June 2014, Accepted: 21 July 2014, Published Online: 10 August 2014 Abstract A series of new nitroimidazole derivatives were synthesized ... Read More »

A Simple UV Spectroscopic Method for the Determination of Sertraline Hydrochloride in Bulk and Tablets

B. Gopi Krishna, A Maruthi, S. Muneer*, B. Mohammed Ishaq, H. Ruksana, Dr. Hindustan Abdul Ahad  Department of Pharmaceutical Analysis, Balaji College of Pharmacy, Anantapur-515001, A. P, India Received: 24 April 2014, Accepted: 6 June 2014, Published Online: 10 August 2014 Abstract A simple, economic, accurate UV method was developed for the estimation of Sertraline HCl (SRT) in bulk and tablet ... Read More »

Salutary Consequence of Spirulina (Arthrospira platensis) for Nourishing & Revitalization

Rajnee1*, Urmila Chaudhary1, Garima Jeswani1, Vikram Singh2, Bhanwar Lal Jat2, CR Chaudhary3, Raaz K Maheshwari4   1Department of Physiology, SN Medical College, Jodhpur, Rajasthan, India 2Department of Botany, SBRM Govt PG College, Nagaur, Rajasthan, India 3Pro-President, Mewar University, Chittorgarh, Rajasthan, India 4 Nodal officers, Geographical Information System, SBRM Govt PG College, Nagaur, Rajasthan, India Received: 10 June 2014, Accepted: 15 July 2014, Published ... Read More »

Meticulousness of Environmental Biotechnology for Decontaminating Wastewater

Krishan Bijrania1, Bhanwar Lal Jat2, Ranjeeta Kumari3, Bhanwar Lal4,   Raaz K Maheshwari*5 1Department of Chemistry, Poornima University, Jaipur, Rajasthan, India 2Department of Botany, SBRM Govt PG College, Nagaur, Rajasthan, India 3Department of Biotechnology, Mewar University, Chittorgarh, Rajasthan, India 4 Department of Chemistry, Singhania University, Zhunzhunu, Rajasthan, India 5Department of Chemistry, SBRM Govt PG College, Nagaur, Rajasthan, India ABSTRACT Water ... Read More »

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