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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Phytochemical Screening and Cytotoxic Activity of Martynia annua L. Leaves Extracts

J. Vinnarasi1, A. Anto Arockia Raj1, G. Leema Rose2*  1Department of Chemistry, St. Xavier’s College (Autonomous), Palayamkottai-627 002, Tamil Nadu, India. 2Department of Chemistry, Holy Cross College (Autonomous), Nagercoil-629 004, Tamil Nadu, India. Abstract The present study was intended to reveal the metabolites presence and determine the cytotoxic potential of various extracts of Martynia annua (Martyniaceae) leaves. The shade dried ... Read More »

Phytochemical Screening and Cytotoxic Activity of Martynia annua L. Leaves Extracts

J. Vinnarasi1, A. Anto Arockia Raj1, G. Leema Rose2* 1Department of Chemistry, St. Xavier’s College (Autonomous), Palayamkottai-627 002, Tamil Nadu, India. 2Department of Chemistry, Holy Cross College (Autonomous), Nagercoil-629 004, Tamil Nadu, India. Abstract The present study was intended to reveal the metabolites presence and determine the cytotoxic potential of various extracts of Martynia annua (Martyniaceae) leaves. The shade dried and powdered leaves ... Read More »

Method Development Validation and Degradation studies of Voriconazole Drug by RP-HPLC Method

Eswara Rao Bammidi*1, Vaikuntarao Lakinani1, Rathnakar Reddy Kura2  1Departmernt of Chemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, A.P., India 2Hetero Research Foundation, Hetero Drugs Ltd, Hyderabad, India Abstract A rapid and sensitive RP–HPLC method with UV detection (260 nm) for routine analysis of voriconazole was developed. Chromatography was performed with mobile phase containing a mixture of acetonitrile and water ... Read More »

Preparation and characterization of Metronidazole and Minocycline HCl Mucoadhesive Gel for the Treatment of Periodontitis

1D.K.Borole*, 1S.N.Sriharsha, 1Yashwant Kumar.D, 2K.S.S.N. Neelima  1Pacific College of Pharmacy, Pacific University (PAHER), Udaipur 2SARC- (Scientific and Applied Research Centre) – Hyderabad, India Abstract The aim of the paper was to develop Metronidazole and Minocycline HCl containing mucoadhesive gel for the treatment of periodontitis. Different Mucoadhesive gels were prepared, using various gelling agents like, Hydroxy ethyl cellulose (HEC), Methyl cellulose ... Read More »

1-Bromobenzimidazole Oxidation of Aliphatic Alcohols -A Kinetic Perspective

B. Ramkumar*1, V. Santhosh Kumar2 and M. Rukmangathan2  *1PG and Research department of chemistry, Govt. Arts College, Thuvakudimalai, Tiruchirappalli, Tamil Nadu, India–620022 2Department of Chemistry, Arasu Engineering College, Kumbakonam, Tamil Nadu, India–612501 Abstract The kinetics of oxidation of aliphatic alcohols by 1-bromobenzimidazole (BBI) has been studied in aqueous acetic acid medium in presence of mercuric acetate. The order of the reaction ... Read More »

Adsorption of Bismarck Brown R Dye from Aqueous Solution onto Activated Carbon Prepared from Delonix Regia Pods shell (Flame Tree)

A. Rajappa1, K. Ramesh2 and V. Nandhakumar3* 1 Department of chemistry, Sri Manakula Vinayagar Engineering College, Madagadipet, Puducherry,India. 2 Department of chemistry, Arasu Engineering College, Kumbakonam, Thanjavur, India. 3*Department of chemistry, A.V.V.M  Sri Pushpam college, Poondi, Thanjavur, India. Abstract Commercial Activated Carbon has been widely used as a good adsorbent. Activated carbon prepared from Delonix regia pods shell (Flame tree) ... Read More »

Single Crystal EPR Studies of Mn (II) Doped in Rubidiumcobalt Sulphatehexahydrate: A Case of Interstitial Location

Hema Ramesh*, S. Sivakumar, M. Rajeswari, A. Rajappa & K. Mageswari  Department of chemistry, Sri Manakula Vinayagar Engineering College, Puducherry,India-605107 Abstract Electron paramagnetic resonance study of Mn2+ ion-doped Rubidiumcobalt sulphatehexahydrate (RCSH) single crystal was carried out at X-band frequency to ascertain its structural properties. EPR spectrum exhibits group of five fine structure transitions each splits into six hyperfine components. The ... Read More »

Studies on Molecular Interaction of Rose Bengal with Surfactants

S. Sankari Devi and Asok Kumar Jana* Department of Chemistry, Kanchi Mamunivar Centre for Post-Graduate Studies, Pondicherry – 605 008, India. Abstract The spectroscopic investigation on anionic dye, Rose Bengal with three different  types of surfactants such as CTAB(cationic), SLS(anionic)  and Triton X-100(TX-100), Tween-20, 40, 60, 80(nonionic) in aqueous media show that Rose Bengal forms a 1:1 molecular  complex with ... Read More »

Synthesis of s-Triazine substituted analogues of 1,5-benzodiazepines of medicinal interest

Vandana Singh*, Aditi Anand and D. Kishore  Department of Chemistry, Banasthali University, Banasthali-304022 (Rajasthan), India Abstract Synthesis of a series of 1,5-benzodiazepines substituted on its 3 and 4 positions with 2’-(amino /ethylamino/ piperidino-(4,6-biscyclopropylamino)) -1,3,5-triazines 12,10,7 and 14 respectively, from 2-methyl-1,5-benzodiazepin-4-one (4) has been described. Keywords: 1,5-Benzodiazepine, 2,4,6-trichloro-1,3,5-triazine.   Read More »

A Study on Phytoremediation of Heavy Metals from Paper Mill Effluent Soil Using Croton Sparsiflorus

B.Ashokkumar1*, S.Jothiramalingam2, S.K.Thiyagarajan3, T.Hidhayathullakhan4 and R. Nalini5  1Research scholar, Khadir Mohideen College, Adirampattinam – 614701, Thanjavur (Dt), Tamilnadu, India. 2 & 3 P.G and Research Department of Chemistry, A. V. V. M. Sri Pushpam College (Autonomous), Poondi-613 503, Thanjavur (Dt), Tamilnadu, India. 4Department of chemistry, Khadir Mohideen College, Adirampattinam – 614 701, Thanjavur (Dt), Tamilnadu, India. 5Department of Chemistry, Periyar Maniammai University, ... Read More »

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