Elanchezhian Balachandravinayagam*, Manivannan Natarajan and Selvanathan Ganesan
Department of Chemistry, A.V.C. College (Autonomous), Mannampandal, Mayiladuthurai, Tamilnadu, India-609305
2′,6′-diphenyl-1,3-dihydrospiro[benzo [d] imidazole-2,4′-piperidine] was synthesized by condensing 2,6-diarylpiperidin-4-one with o-phenylene diamine. The synthesized compound was characterized by IR, Mass and NMR spectral studies. NMR spectral assignments are made unambiguously by their one-dimensional (1H and 13C NMR) and two-dimensional (1H–1H COSY and NOESY) NMR spectra. The spectral data suggest that the compound adopt chair conformation with equatorial orientation of all the substituents. The target compound exhibited an excellent free radical scavenging activity on the stable DPPH free radical (71.6 %).
Keywords: Benzoimidazole, Homocosy, Noesy, conformation, Antioxidant and DPPH.