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Category Archives: Pharmaceutical Sciences and research inventions

Advancements of Diagnosing the River Blindness

V. Saichitra Prathyusha* Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore-524346 Abstract Riverblindness  is  also  called  onchocerciasis . It   has historically   been one of the leading causes of infectious blindness worldwide. It is endemic  to  tropical  regions  both in Africa  and latin  amercia  and  in the   yemen . onchocerciasis  is caused  by infecrtion  waith the filarial  parasite onchocerca volvulus.  The infection ... Read More »

Evaluation of the Antioxidant and Antimicrobial activity of the Myrica nagi Leaf extracts

Saritha Chandra*, Maredupalli Bharath, Maru Keerthi, Maruthi Vishnu Pooja, Talari Bhagya Lakshmi, Yesupaku Rakesh Narayana Pharmacy College, Chintha Reddy Palem, Nellore, Andhra Pradesh, India A B S T R A C T Nutraceutical is a combination of two words nutrition and pharmaceutical which provides health and medical benefits, including the prevention and treatment of diseases. These are products derived from ... Read More »

Antiurolithic Activity of Syzygium Cumini on Ethylene Glycol Induced Kidney Stones in Male Albino Rats

k. Susmitha*, Dr. P. Venkatesh, V. Monika Chowdary, V. Pooja, V. Arathi, A. Vijaya, P. Giri babu, K. Vamsi Abstract The kidney stone is one of the most widely spreading renal disorders in the world. The present study was undertaken to evaluate the efficacy of Scyzygium Cumini seeds in reducing the growth of calcium oxalate stones in ethylene glycol induced ... Read More »

Coumarin Oxadiazole Derivatives: Review on Antimicrobial Activity

Megha.P, Vidya A.D, T. Yunus Pasha,  Ramesh Dhani* Department of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G Nagar-571448, Nagamangala Taluk, Mandya, Karnataka. Abstract Emergence of resistance by microbial and fungal stains towards existing antimicrobial agents is one of the major complication as well as stimulation to developing the latest class of antimicrobial agents possessing strong activity compared ... Read More »

Design and Characterization of Candesartan cilexitil by using different hydrotropic agents

B. Venkateswara Reddy* Department of Pharmaceutics, St Paul’s College of Pharmacy, Thukayamjal, Ranga Reddy, Telangana, India. Abstract The aim of the present study is to increase the solubility of Candesartan Cilexitil by using different hydrotropic agents. Candesartan Cilexitil acts as antihypertensive agent. In this study increasing the solubility of drug by using different hydrotropic agents like sodium benzoate, sodium acetate, ... Read More »

Development and Validation of Stability indicating HPLC method for simultaneous estimation of `Metformin and Ertugliflozin

P. Harsha Hruditha*, Dr. P. Jayachandra Reddy Krishna Teja Pharmacy College, Renigunta Road, Tirupati, Andhra Pradesh 517506 ABSTRACT A simple, Accurate, precise method was developed for the simultaneous estimation of the Ertugliflozin and Metformin in Tablet dosage form. Chromatogram was run through phenomenex c18 150 x 4.6 mm, 5m. Mobile phase containing Buffer: Acetonitrile taken in the ratio 60:40 was ... Read More »

Formulation and Evaluation of Floating tablet of captopril

D. Lakshmi1, K. Sunil kumar2 1Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhrapradesh, India. 2Associate Professor, Department of Pharmaceutics, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. ABSTRACT The primary objective was to formulate & evaluate gastroretentive floating tablets of the Captopril by using different polymers in different ratios. Captopril is a potent, competitive ... Read More »

Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Pregabalin and Methylcobalamin in Formulation by QBD Approach

Aasadi Balaji*, G. Dharmamoorthy, G. Aruna, KV Nanda Kumar, P. Jaya Chandra Reddy Krishna Teja Pharmacy College, Chadalawada Nagar, Renigunta Road Tirupati-517506 ABSTRACT By considering the current regulatory requirement for an analytical method development, a simple, precise, accurate, linear and rapid Reverse Phase High Performance Liquid Chromatographic (RP-HPLC) method for the simultaneous quantitative estimation of Pregabalin 75mg and Methylocobalamin 750µg ... Read More »

Photochemical Study of Medicinal Compound (N-2 (thaizolyl) sulfanilamide,)

Meena Chourey* Oriental Institute of Science and Technology Bhopal, India – 462021 ABSTRACT N-2(thaizolyl) sulfanilamide, it is common hetero atoms are N,O and S.Sulphonamide are synthetic chemotherapeutic agents which contain a sulphonamide (SO2- NH2)group in their structures. The Photochemical reaction of N-2(thaizolyl) sulfanilamide it is in different medium, for example of, neutral medium, acidic medium and alkaline medium It is ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Sildenafil and Dapoxetine by Using RP-HPLC Technique

Prathap.B1*, V.HariBaskar1, B.Kumar1, D.Ramesh2, M.Maheswari1, S.Harika1, P.Sonalika1 1Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Nellore, Andhra Pradesh – 524346. 2Department of Pharmaceutical Chemistry, Sri Adichunchanagiri College of Pharmacy, Adichunchanagiri University, B.G Nagar-571448, Mandya, Karnataka. ABSTRACT A new RP-HPLC method was developed for the simultaneous estimation of sildenafil and Dapoxetine in pharmaceutical dosage form. The chromatographic conditions were successfully developed ... Read More »

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