Thursday , 13 June 2024

Antiurolithic Activity of Syzygium Cumini on Ethylene Glycol Induced Kidney Stones in Male Albino Rats

k. Susmitha*, Dr. P. Venkatesh, V. Monika Chowdary, V. Pooja, V. Arathi,
A. Vijaya, P. Giri babu, K. Vamsi

The kidney stone is one of the most widely spreading renal disorders in the world. The present study was undertaken to evaluate the efficacy of Scyzygium Cumini seeds in reducing the growth of calcium oxalate stones in ethylene glycol induced model. Upon administration of Furosemide (20mg/kg), alcoholic extract of Scyzygium Cumini (200 and 400mg/kg) on hyperoxaluria rats shows the significant activity in decrease kidney stones and serum levels (calcium, phosphorous, Creatinine, urea) both not that as standard drug Furosemide.
Keywords: Syzygium cumini, calcium oxalate, ethylene glycol, Furosemide, hyperoxaluria.

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