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K. Jyosthsna, K. Umasanker Krishna Teja Pharmacy College, Tirupathi, Andhra Pradesh, India ABSTRACT Clobazam belongs to the 1, 5-benzodiazepine class of drugs and is expected to have a better side-effect profile compared to older 1,4-benzodiazepines. It is a BCS class II drug having higher half-life. To improve the biological performance of Clobazam solid dispersion with oral disintegrating tablet was formulated ... Read More »
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Category Archives: Pharmaceutical Sciences and research inventions
Antimicrobial Activity of the Extract of Stem Bark of Diospyrosebenum
Amith Kumar B1*, Mrunal K Sirshat2, U. Srinivasa3 1Research Scholar, Pacific Academy of Higher Education and Research University, Udaipur. 2Dean and Professor, Madhav University Aburoad, Udaipur, India 3Professor and HOD, Dept. of Pharmacognosy, Srinivasa College of Pharmacy, Mangalore. A B S T R A C T In this study, the ethanol extract of D. ebenum was tested for its antimicrobial ... Read More »
Biochemical Studies on Antidiabetic Effect of Papaverine Psychosis Associated Diabetes Mellitus in Sprague-Dawley Rats
Sravani Batchu*, E. Bhavya VISTAS Vels University, Department of Pharmacy, Pallavaram, Chennai VISTAS Vels University, Department of Pharmaceutical Sciences, Pallavaram, Chennai A B S T R A C T Papaverine is an opium alkaloid of the benzylisoquinoline group, of low toxicity and non-habit forming. It is used in the treatment of conditions associated with smooth muscle spasm. PDE-10A expressed in ... Read More »
Phytopharmacological Review on Epipremnum Aureum
G. Sindhu*, P. Joshna, D. Ravinanda, T. Usha Kiran Reddy, Ch. Appa Rao SVU College of Pharmaceutical Sciences, S.V. University, Tirupati, A.P, India ABSTRACT Plants belonging to Araceae family are commonly known as “aroids’’ as they contain crystals of calcium oxalate and toxic proteins which can cause intense irritation and poisoning if the raw plant tissue is eaten. They range ... Read More »
Analytical Method Development and Validation of Doravirine in Pharmaceutical Dosage Form by RP-HPLC
V. Hari Baskar*, SK. Karishma Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore–524346 ABSTRACT A new method was established for estimation of Doravirine by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Doravirine by using Agilent column (4.6×150mm) 5µ, flow rate was 1.0 ml/min, mobile phase ratio was Phosphate buffer: ... Read More »
Regulations and Management of Biological Products
B. Abhirami*, C.P. Sreekanth Reddy1, J. Praveen kumar2, E. Vijay Kumar3 *Krishna Teja Pharmacy College, Tirupati, A.P. 1Assistant Professor, Krishna Teja Pharmacy College, Tirupati, A.P 2Associate Professor, Krishna Teja Pharmacy College, Tirupati, A.P 3Assistant Professor, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, A.P ABSTRACT The regulation of the biological and biotechnological products constitutes a significant challenge, since they are part of ... Read More »
Development and Validation of Stability Indicating RP-HPLC Method for the Determination of Irrinotecan in Bulk and It’s Pharmaceutical Dosage Form
Bonagiri Pavani*1, Dr. C. Hari kumar2, Y. Kesava3, Dr.B.Mohammed Ishaq4 1,2,3Vasavi Institute of Pharmaceutical Sciences, Kadapa, A.P, India 4Santhiram College of Pharmacy, Nandyala, A.P, India ABSTRACT A simple, sensitive, and specific reverse phase high performance liquid chromatographic method was developed and validated for the determination of Irinotecan in bulk and tablet dosage forms. The HPLC separation was carried out by ... Read More »
An Evaluation and Comparative Study of Regulatory of Regulatory Requirements for Registration of Generic injectables in USA, European Union and Canada
D.S. Naveen Kumar*1, J. Praveen Kumar2 *1Krishna Teja Pharmacy College, Tirupati 2Associate professor, Krishna Teja Pharmacy College, Tirupati A B S T R A C T Regulatory affairs professionals are key players in drug development to approve and through life cycle management of a drug. They are the primary communications link between the company and agencies such as FDA, MHRA, ... Read More »
Effect of EU Regulations on Innovation and Marketing Authorisation of Orphan Drugs for Children
R. Charitha*, J. Praveen Kumar1, E. Vijay Kumar2 *Krishna Teja Pharmacy College, Tirupati, A.P., India 1Associate Professor, Krishna Teja Pharmacy College, Tirupati, A.P., India 2Assistant Professor, Srinivasa Institute of Pharmaceutical Sciences, Proddatur, A.P., India A B S T R A C T No single definition for orphan diseases exists worldwide, but it is generally a disease that affects a small ... Read More »
Design and Evaluation of Sustained release matrix tablets for Tramadol Hydrochloride (TH) Melt granulation technique
B. Ranganayakulu*, V.Krishnaveni1, Dr. S. Mohammed Yusuf2 *,2 Associate Professor, Srinivasa institute of Pharmaceutical Sciences, Proddatur, A.P., India. 1Srinivasa institute of Pharmaceutical Sciences, Proddatur, A.P. India. A B S T R A C T The objective of the present investigation was to design and evaluate sustained release matrix tablets for Tramadol Hydrochloride (TH) with Compritol 888 ATO and Precirol ATO ... Read More »
