Thursday , 29 July 2021

Tag Archives: Validation

A Review on validation of Autoclave, Membrane Filtration

Author Details B. Venkateswara Reddy*, B. Rasmitha Reddy, K. Navaneetha St.pauls College of Pharmacy, Turkayamjal, R.R (Dist) -501510, Andhra Pradesh, India Abstract Validation is one of the important steps in achieving and maintaining the quality of the final product batch after batch. Without equipment, we cannot manufacture a product. If equipment is validated, we can ensure that our product is ... Read More »

Development and Validation of UV Spectrophotometric Method of Febuxostat in Bulk and Tablet Formulations

About author Raviteja, N. SambaSiva Naik*, Gayathri,  Sd.Fathima Zahera Narasaraopet Institute of Pharmaceutical Sciences, Narasaraopet, Andhra Pradesh, India E-mail: sambasiva.nunsavathu@gmail.com Abstract The present research works discuss the development of a UV estimation method for febuxostat. Simple, fast, accurate and cost efficient and reproducible. Spectrophotometric method has been developed for the estimation of febuxostat in bulk and tablet formulations. The wave ... Read More »

Validated RP-HPLC Method for the Quantification of Anidulafungin In Bulk Sample and Parenteral Dosage Form and its Application to forced Degradation Studies in Bulk Sample

About author Lohita M*, Jaya Preethi P, Swetha K, Vengal Rao P, Naresh D, Amrutha V Department of Pharmacy, Sree Vidyanikethan College of Pharmacy, Sri Sainath nagar, Tirupati-517102. E-mail:  lohitapharma11@gmail.com Abstract A simple, selective, precise and stability-indicating high-performance liquid chromatographic method of analysis of Anidulafungin in pharmaceutical dosage form was developed and validated. The solvent system consisted of acetonitrile: water: 0.1% v/v ... Read More »

Spectrophotometric Simultaneous Estimation of Valsartan and Hydrochlorothiazide in Pharmaceutical Dosage Form using Mixed Hydrotropic Solubilisation Approach

About author Jyoti  Vilas  Jadhav*,  Kishorkumar  Burade Govt.  College  of  Pharmacy,  Vidyanagar  Karad, Satara,  Maharashtra- 415124,  India Email: jadhavjyoti255@gmail.com Abstract                       Two validated UV spectrophotometric methods for the simultaneous estimation of  Valsartan  and  Hydrochlorothiazide  in  pure  powder  and  in  two  component  tablet  dosage  form  have  been  developed,  utilising  simultaneous  equation  and  absorbance  ratio  method.  The  ... Read More »

Isocratic Reverse Phase HPLC Method-Determination and Validation of Cilostazol

About author K.Krishna Chaitanya*, D. Gowri Sankar, Samson Israel. D, CH. Narasimha Kumar, BalaKumar.K, CH.Harsha vardhan reddy. Pharmaceutical Analysis & Quality Assurance Division A.U. College of Pharmaceutical Science, Andhra University, Visakhapatnam-530003 E-mail: chaitukoppula@gmail.com Abstract A simple isocratic HPLC method has been developed and subsequently validated for determination of Cilostazol in pharmaceutical dosage forms. The method employs an Agilent Zorbax Eclipse ... Read More »

Estimation of Rabeprazole Sodium in tablet dosage form by using UV-VIS Spectrophotometer

About author Vipin Kumar Agrawal *, Alok Singh , Pravesh Kumar, Jyoti Rai, Inamullah Department of Pharmaceutics, Invertis Institute of Pharmacy, Invertis University, Bareilly-243 123, Uttar Pradesh, India Department of Pharmaceutical Chemistry, Invertis Institute of Pharmacy, Invertis University, Bareilly-243 123, Uttar Pradesh, India *E-mail: vipin.a@invertis.org Abstract Rabeprazole sodium (RSM) is a proton pump inhibitor used against peptic ulcer disease to ... Read More »

METHOD DEVELOPMENT AND VALIDATION OF EFAVIRENZ IN BULK AND PHARMACEUTICAL TABLET DOSAGE FORM BY USING UV–VISIBLE SPECTROPHOMETRIC METHOD

ABOUT AUTHOR Somsubhra Ghosh*, B. Rajni,  S. Vidyadhar, Dr. David Banji Department of Pharmaceutical Analysis and Quality Assurance, Nalanda College of pharmacy, Cherlapally, Nalgonda, Andhra Pradesh, India. E-mail : som_subhra_ghosh@yahoo.co.in ABSTRACT The present research work discusses the development of UV Spectrophotometric method for the determination of Efavirenz  in bulk and pharmaceutical capsule dosage form. The present method is simple, rapid, ... Read More »

Method development and validation for the simultaneous estimation of Nebivolol hydrochloride and S (-) Amlodipine besilate in tablet dosage form by RP – HPLC

About author Prabhakaran. V.*, Sekar. S., Baskar.E., Raghuprasath. V.R. Formulation Research and Development Department, The Madras Pharmaceuticals, Karapakkam, Chennai, Tamil Nadu, India. Email: rnd@madraspharma.com ABSTRACT High Performance Liquid Chromatography method was developed and validated in a simple, specific and precise manner for Nebivolol HCl and Amlodipine besilate in a combined solid dosage form. Nebivolol hydrochloride, a long acting, cardioselective β ... Read More »

METHOD DEVELOPMENT AND ITS VALIDATION FOR QUANTITATIVE SIMULTANEOUS DETERMINATION OF DEXAMETHASONE AND GATIFLOXACIN IN OPHTHALMIC SOLUTION BY RP-HPLC

About author : Ankit Agarwal*, Subhash Dadhich, Sunil Kumar Tiwari, Kashyap Nagariya R & D Division, Ahlcon Parenterals (I) Ltd., Bhiwadi, Rajasthan, India *e-mail: ankitagarwal005@gmail.com ABSTRACT : To develop a simple, rapid and accurate HPLC method for simultaneous quantitative determination of Dexamethasone and Gatifloxacin in ophthalmic solution. Chromatographic separation was achieved with PDA detector using Inertsil C18, 250 x 4.6mm, ... Read More »

Method Validation in Pharmaceutical Analysis

Method Validation in Pharmaceutical Analysis J. Ermer and J. H. McB. Miller Methods used in pharmaceutical analysis must be sufficiently accurate, specific, sensitive and precise to conform to the regulatory requirements as set out in the relevant guidelines of “The International Conference of Technical Requirements for the Registration of Pharmaceutical for Human Use ” (ICH), which are applied by the ... Read More »

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