Monday , 16 May 2022

Tag Archives: Validation

Reverse Phase High Performance Liquid Chromatographic Technique for the Determination of Pantoprazole in Pure and Its Dosage Forms

Dr. Hareesh Dara, Meesa Rajendar, Dr. Ampati Srinivas St. John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana, India A B S T R A C T A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Pantoprazole, in its pure form as well as in tablet dosage form. Chromatography was carried out on ... Read More »

Analytical Method Development and Validation for the Determination of Brinzolamide and Brimonidine Using Reverse Phase HPLC Method in Bulk and Pharmaceutical Dosage Form

Dr R. Vani1*, Amena Samreen2, Humera Tabassum3, Dr M.sunitha4* 1Head of Department, Pharmaceutical Analysis and QA, Shadan Women’s College of Pharmacy, Hyderabad. 2Post-Graduate Student, Shadan Women’s College of Pharmacy, Hyderabad. 3Post-Graduate Student, Shadan Women’s College of Pharmacy, Hyderabad. 4Principal, Shadan Women’s College of Pharmacy, Hyderabad. ABSTRACT In RP-HPLC method, the conditions were optimized to obtain an adequate separation of eluted ... Read More »

Simultaneous Estimation of UV Spectroscopy and Method Development and Validation for Lansoprazole and Domperidone by RP-HPLC

Sanju Srinivas1, Marium Nazneen2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana ABSTRACT A new method was established for simultaneous estimation of Lansoprazole and Domperidone by RP-HPLC method. The chromatographic conditions were  successfully developed  for  the  separation  of  Lansoprazole and Domperidone by using Xterra C18 5µ m (4.6*250mm) column, ... Read More »

Analytical Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms by RP-HPLC

G. Madhavi1, S. Sravani1, G. Nikithareddy1, V. Mounika1, B. Divya1, M. Chaithanya*1, Bijjiga Sravanthi2 1Bojjam Narasimhulu Pharmacy College, Sayeedabad, Hyderabad, Telangana-500059. 2KP Labs, Kothapet, Hyderabad-500035 A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid Chromatographic Method for simultaneous estimation of Valsartan and Sacubitril in ... Read More »

Validation of Developed Analytical Method for Valsartan Floating Tablets by Reverse Phase High Performance Liquid Chromatography

C. Saravanan*1, M. Purushothaman2 1Sun Rise University, Alwar, Rajasthan – 301030, India 2Scient Institute of Pharmacy, Ibrahimpatnam, Ranga Reddy (Dt), Hyderabad, Talangana-501 506, India. A B S T R A C T Aim of the present investigation was to validate a new analytical, simple, sensitive, selective and precise High Performance Layer Chromatograpic (HPLC) method for the estimation of Valsartan in ... Read More »

Method Development and Validation of Omeprazole by RP-HPLC Method in Bulk and Its Pharmaceutical Dosage Form

Nagadani Kalyani*, R. Kiran Jyothi, Dr. K.B Chandra Sekhar Department of Pharmaceutical Analysis, JNTUA- Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515001, A. P, India A B S T R A C T Omeprazole is a proton pump inhibitor ﴾PPI﴿ and a potent inhibitor of gastric acidity which is mostly used in the therapy of gastroesophageal reflux and peptic ulcer disease. ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Tablets

P. Vamsi Reddy*1, V. Asha Ranjani2, R. Chandra Sekhar3, M. Shyam Sundar3 1Centre for Pharmaceutical Sciences, IST, JNTU, Hyderabad -500085 2MLR Institute of Pharmacy, Dundigal (v), Hyderabad-500043 3Department of Pharmaceutical analysis& Quality assurance, OU, Hyderabad-500007 A B S T R A C T The present paper describes a new, simple, precise, and accurate RP-HPLC method for simultaneous estimation of ledipasvir ... Read More »

Stability Indicating RP-HPLC Method for the Simultaneous Determination of Anti-Infectious Vials Containing Sulbactam and Ceftazidime in Pharmaceutical Dosage

L Kalyani1 and Chava Venkata N Rao2* 1Department of Chemistry, NRI Institute of Technology, Perecherla, Guntur, Andhra Pradesh 2Department of Chemistry, NRI Institute of Technology, Pothavarappadu, Andhra Pradesh A B S T R A C T A simple, accurate, rapid, and stability-indicating RP-HPLC method for a combination of Sulbactam and Ceftazidime has been developed and subsequently validated in commercial formulation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Cefadroxil and Ambroxol Hydrochloride by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India Abstract A Simple and rapid stability indicating RP-HPLC method was developed for the simultaneous determination of Cefadroxil and Ambroxol in bulk and pharmaceutical dosage form. A chromatographic separation of the two drugs was achieved with a Symmetry C18 (4.6 × 250 mm, 5 μm partical size, make: Xterra) ... Read More »

Design, Development and Validation of Bioanalytical Methods for Pharmaceutical Formulations – Review

Subramani1, M. Purushothaman*2 1Alwar College of Pharmacy, Sun Rise University, Alwar, Rajasthan – 301030, India 2Vasavi Institute of Pharmaceutical Sciences, Kadapa-516247, India A B S T R A C T Any method developed for the analysis of analytes in biological fluids must yield consistent results despite the variations in conditions during the course of a project. An ideal bioanalytical method ... Read More »

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