Wednesday , 19 June 2024

Tag Archives: Validation

RP-HPLC Method Development and Validation for the Simultaneous Estimation of Ceftazidime and Sulbactam in Bulk and Pharmaceutical Dosage

Vishal Bharat Babar1,*, Srikanth Kumar Karumanchi2, B. Siva Sai Kiran3 1*Dattakala College of Pharmacy, Swami-Chincholi, Bhigwan-413130, Pune Dist., Maharashtra, India. 2V. V. Institute of Pharmaceutical Sciences, Gudlavalleru-521356, Krishna Dist., Andhra Pradesh, India. 3JNTUA-Oil Technological & Pharmaceutical Research Institute, Ananthapuramu-515002, Andhra Pradesh, India. A B S T R A C T The current investigation was pointed at developing and progressively validating ... Read More »

Stability Indicating Method Development and Validation for Simulatenous Estimation of Zopolrestat and Pregabalin by Using RP-HPLC

Vishal Bharat Babar1,*, Srikanth Kumar Karumanchi2, B. Siva Sai Kiran3 1*Dattakala College of Pharmacy, Swami-Chincholi, Bhigwan-413130, Pune Dist., Maharashtra, India. 2V. V. Institute of Pharmaceutical Sciences, Gudlavalleru-521356, Krishna Dist., Andhra Pradesh, India. 3JNTUA-Oil Technological & Pharmaceutical Research Institute, Ananthapuramu-515002, Andhra Pradesh, India. A  B  S  T  R A C T In this study, the active pharmaceutical components of Zopolrestat and ... Read More »

Estimation of Levetiracetam in Human K2EDTA Plasma in range from 0.253 µG/ML to 35.060 µG/ML by using LC-MS/MS

Narendra Kumar Reddy Kolli*, Swetha Polagani, Sandhya, Rathnakar Nathi2 Sri Vani School of Pharmacy, Chevuturu, Vijayawada, AP. India Wuxi DEE Pharmaceuticals Ltd. Xishan District, Wuxi, Jiangsu province, PRChina A B S T R A C T A simple, sensitive and selective method for the determination of Levetiracetam by using rapid high-performance liquid chromatography/positive electroscopy ionization tandem mass spectroscopy was developed. ... Read More »

HPLC Estimation of Vildagliptin in Bulk and Pharmaceutical Formulations

Rajkiran Kolakota*, P. Anil Naidu, Uha Rani Duppala Department of Pharmaceutical Analysis, Sri Sivani College of Pharmacy, NH-16, Chilakapalem Jn, Srikakulam-532402, AP  A B S T R A C T A simple and reproducible method was developed for Vildagliptin by Reverse Phase High Performance Liquid Chromatography (RP-HPLC). Vildagliptin was separated on Altima C18 column (150 x 4.6mm, 5μm), using Phosphate ... Read More »

HPLC Estimation of Levofloxacin in Bulk and Pharmaceutical Formulations

Rajkiran Kolakota*, Y. Rupavathi Department of Pharmaceutical Analysis, Sri Sivani College of Pharmacy, NH-16, Chilakapalem Jn, Srikakulam-532402, A.P ABSTRACT A HPLC method was developed and validated to determine trace amounts of levofloxacin related substances & degradation products in its formulation. Separation of levofloxacin from impurity A, impurity B, impurity C and unknown degradation products was achieved on a YMC-Pack Pro ... Read More »

HPLC Estimation of Paroxetine in Bulk and Pharmaceutical Formulations

Rajkiran Kolakota*, P. Anil Naidu, Uha Rani Duppala Department of Pharmaceutical Analysis, Sri Sivani College of Pharmacy, NH-16, Chilakapalem Jn, Srikakulam-532402, AP A  B  S  T  R A C T A simple and reproducible method was developed for Paroxetine by Reverse Phase High Performance Liquid Chromatography (RP-HPLC). Paroxetine was separated on ODS column (150 x 4.6 mm, 5μm), using Phosphate ... Read More »

Bioanalytical Method for Quantification of Torsemide in Human Urine Using LC-MS/MS

S. Satheshkumar*1, V. Muruganantham2 1Ph.D. Scholar, Department of Pharmaceutics, College of Pharmacy, Vinayaka Mission’s College of Pharmacy, Salem- 636008, Tamilnadu, India 2Professor, Department of Pharmaceutics, College of Pharmacy, Vinayaka Mission’s College of Pharmacy, Salem- 636008, Tamilnadu, India. A B S T R A C T Anaccurate and simple method was developed using high performance liquid chromatography with electron spray ionization ... Read More »

Analytical Method Development and Validation of Mupirocin and Bromelain in API and Its Dosage Form by RP-HPLC

N. Karnakar1, B.Manisha2, R. Narsimha Rao3, P. Amani4 1,2,3,4Venkateshwara Institute of Pharmaceutical Sciences, Charlapally, Nalgonda, Telangana. W. J. Pharm. Biotech., 2021, 8(1): 01-04 A B S T R A C T A new method was established for simultaneous estimation of Mupirocin and Bromelain by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Mupirocin and Bromelain by ... Read More »

RP-HPLC Method Development and Validation for Estimation of Metadoxine in API and Pharmaceutical Dosage form

R. Chaitanya*, D. Vijaya Durga, Dr. K. Padmalatha Department of Pharmaceutical Analysis, Vijaya Institute of Pharmaceutical Sciences for women, Enikepadu, Andhra Pradesh. A B S T R A C T A rapid, specific, accurate and precise reverse phase high performance liquid chromatographic method has been developed and validated for Metadoxine, in its pure form as well as in tablet dosage ... Read More »

Development and Validation of New Analytical Method for the Simultaneous Estimation of Lisinopril and Amlodipine in Pharmaceutical Dosage Form by UV Spectrophotometry

Pavan Kumar.V*, P. Jyoshna, P. Nageena, E. Sandhya Mahalakshmi, K. Siva Kumar, A. Subha Jahnavi, A. Tharun Sai Department of Pharmaceutical Analysis, Seven Hills College of Pharmacy, Venkatramapuram, Tirupati-517561      A B S T R A C T An elementary, valid, Speedy and decisive strategy was developed to determine Lisinopril and Amlodipine quantitatively in combined pharmaceutical dosage forms. The method was ... Read More »

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