A. Hima Bindu, M. Navaneetha, K. Prasad, K. Triveni, S. Ramakrishna, B. Nagendra Babu, Naresh Gorantla*
Department of Pharmaceutics, Balaji College of Pharmacy, Ananthapuramu, Andhra Pradesh, India.
A B S T R A C T
In this present work systemic phytochemical investigation of Coccinia grandis work done and it is also evaluated for antidepressant activity by the aqueous extract of leaves. In phytochemical investigation of the plant leaves we found that it contains alkaloids, glycosides, tannins, reducing sugars, steroids, flavonoids, carbohydrates. The leaves were extracted with water by using soxhlet apparatus and the crude extracts were administered to albino rats of six groups. Before administration of crude extract, depression was induced to all groups by using forced swim test apparatus method and this it is tested for its activity.
Keywords: Forced Swim test Apparatus, coccinia grandis, anti depressant activity, phyto chemical, soxhlet apparatus, albino rats.