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Nair Ayana Ramesh1, Dr. D. Naresh1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The estimation of metformin and gemigliptin was done by RP-HPLC. The Phosphate buffer was ... Read More »
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Category Archives: Chemical Sciences and Chemical research
A Validated RP- HPLC Method for the Simultaneous Estimation of Empagliflozin and Linagliptin in its Bulk and Pharmaceutical Dosage Forms
Jayalaxmi1, Dr. T. Rajesh1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T A new method was established for simultaneous estimation of Empagliflozin and Linagliptin by RP-HPLC method. The ... Read More »
A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms
Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »
Analytical Method Development and Validation for Elbasvir and Grazoprevir in Combine Phaarmaceutical Dosage forms by RP-HPLC
Abilash Reddy Vancha1, Dr. D. Naresh1, P. Sowjanya1, Dr. Gampa Vijaya Kumar*2 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Professor and Head, Department of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T HPLC is at present one of the most sophisticated tool of the ... Read More »
Medicinal Chemistry of Tyrosine Kinase Inhibitor Drug: A Review
Amol S Dighe*1, Sagar D. Magar1, Nachiket S. Dighe2 Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Pravaranagar, Loni, Maharashtra, India A B S T R A C T Tyrosine kinases are a part of many cell functions, including cell signaling, growth, and division. These enzymes may be too active or found at high levels in some types of ... Read More »
N-[4-[Benzyloxy] benzyl]-benzenemethaneamines with High Biological Activity against Intracellular Trypanosoma cruzi and Leishmania infantum Amastigotes
Gabrielle Frizzo Souza1, Simon Bernhard Cämmerer1*, Caio Haddad Franco2, Laura Maria Alcantara2, Carolina Borsoi Moraes2, Lucio Holanda Freitas-Junior2* 1Instituto de Química, Universidade Estadual de Campinas, Rua Monteiro Lobato S/N, Cidade Universitaria Zeferino Vaz, Barão Geraldo, CP 6154, CEP 13083-970, Campinas, São Paulo, Brasil. 2Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Rua Giuseppe Maximo ... Read More »
Development and Validation of Stability Indicating RP-HPLC Method for Amoxicillin and Clavulanate Potassium Related Impurities in Pharmaceutical Dosage Forms
Konda Sidda Reddy*1, Ramamohana Reddy Maddike2, J Sreeramulu2 1Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India. 2Departments of Chemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India. A B S T R A C T A simple, cost effective, stability indicating reversed-phase High Performance Liquid Chromatography method was developed for separation and quantification of seventeen specified known related impurities in ... Read More »
Multiple Personality Disorder (MPD)
Alladi Vinod Babu*, Saritha Chandra, Dr. P. Venkatesh Jagan’s College of Pharmacy, Jangala Kandriga (V), Muthukur (M), SPSR Nellore dist-524348 A B S T R A C T Multiple personality describes a state in which the integrated functioning of a person’s identity, including consciousness, memory and awareness of surroundings, is disrupted or eliminated. Dissociation is a mechanism that allows the ... Read More »
A Review on Phytochemistry and Biological Assays of Rauvolfia Serpentina (L). Benth. ex Kurz.
Chinju Merin Abraham* Lecturer in Botany, Department of Botany, Catholicate College, Pathanamthitta, Kerala- 689 645 A B S T R A C T Rauvolfia serpentina is an important medicinal plant with a myriad of pharmacological activities. The plant is famous for curing various ailments due to the presence of alkaloids, carbohydrates, flavonoids, glycosides, phlobatannins, phenols, resins, saponins sterols, tannins and ... Read More »
Kinetics and Oxidation Mechanism of Pentaamminecobalt (III) Complexes of α-Hydroxy Acids by Isoquinolinium Dichromate in Micellar Mmedia
Palanivela, P. Rajkumar*b and K. Subramanic aDepartment of Chemistry, Government Arts College (Men) (Affiliated to Periyar University, Salem) Krishnagirii-635001, Tamilnadu, India. bDepartment of Chemistry, Priyadarshini Engineering College (Affiliated to Anna University, Chennai), Vaniyambadi-635751, Vellore District, Tamilnadu, India. cPG & Research Department of Chemistry, Islamiah College (Affiliated to Thiruvalluvar University, Vellore), Vaniyambadi-635752, Vellore District, Tamilnadu, India. A B S T R A ... Read More »
