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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Stability Indicating RP-HPLC Method for the Simultaneous Determination of Anti-Infectious Vials Containing Sulbactam and Ceftazidime in Pharmaceutical Dosage

L Kalyani1 and Chava Venkata N Rao2* 1Department of Chemistry, NRI Institute of Technology, Perecherla, Guntur, Andhra Pradesh 2Department of Chemistry, NRI Institute of Technology, Pothavarappadu, Andhra Pradesh A B S T R A C T A simple, accurate, rapid, and stability-indicating RP-HPLC method for a combination of Sulbactam and Ceftazidime has been developed and subsequently validated in commercial formulation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Candesartan and Hydrochlorothaizide by RP-HPLC Method Pharmaceutical Dosage Form

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006 Abstract A new method was established for simultaneous estimation of Candesartan cilexitil and Hydrochlorothiazide by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Candesartan cilexitil and Hydrochlorothaizide by using Zodiac sil C18 column (4.6×150mm)5µ, flow rate was 1ml/min, mobile phase ratio was ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Cefadroxil and Ambroxol Hydrochloride by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India Abstract A Simple and rapid stability indicating RP-HPLC method was developed for the simultaneous determination of Cefadroxil and Ambroxol in bulk and pharmaceutical dosage form. A chromatographic separation of the two drugs was achieved with a Symmetry C18 (4.6 × 250 mm, 5 μm partical size, make: Xterra) ... Read More »

Plastic Waste Management in Municipalities

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India Abstract Solid waste management is one of the most challenging issues in municipalities, which are facing a serious pollution problem due to the generation of huge quantities of solid waste. Various studies reveal that about 90% of Municipality Solid Wast (MSW) is disposed ... Read More »

RP-HPLC Method Development and Validation for estimation of Metformin, Voglibose, Glimepiride in Bulk and Combined Tablet Dosage Forms

Trupti C. Mahajan*1, Swapnil B. Deshmukh1, Vilas L. Badgujar1, Priyanka N Chhajed1,  Jayshri A. Patil2 1DCS’S A.R.A College of Pharmacy, Nagaon, Dhule 2NES’S Gangamai College of Pharmacy, Nagaon, Dhule A B S T R A C T Background: A simple, sensitive, linear, precise, and accurate method by gradient reversed-phase-high performance liquid chromatography for the simultaneous estimation of metformin (MET), voglibose ... Read More »

Method Development and Validation of Paracetamol, Guaifenesin, Ambroxol Hydrochloride, Phenylephrine Hydrochloride and Chlorpheniramine Maleate in Bulk and Combined Dosage Form Using RP-HPLC Technique

Swapnil B. Deshmukh*, Vilas L Badgujar, Priyanka N Chhajed, Trupti C. Mahajan, Tanvirahmad J. Shaikh DCS’S A.R.A College of Pharmacy, Nagaon, Dhule A B S T R A C T An RP-HPLC method for the simultaneous determination of Paracetamol, Guaifenesin, Ambroxol hydrochloride, Phenylephrine hydrochloride and Chlorpheniramine maleate in tablets was developed and validated ® as per ICH and FDA guidelines. ... Read More »

Evaluation of Anti-inflammatory activity of Ethanolic leaf extract of Tephrosia villosa

Sumaltha*, K. Venugopal Department of Pharmaceutical Chemistry, Nirmala College of Pharmacy, Kadapa- 516002, India. A B S T R A C T Tephrosia villosa belongs to the family Fabaceae. It is one of the most important plants used in the indigenous system of medicine. To study the anti-inflammatory activity of ethanolic leaf extract of T.villosa using Carrageenan induced model. Anti-inflammatory ... Read More »

Synthesis, characterization and Biological Evaluation of 3,4-bis(substituted-Phenyl)-7-(2,6- dichloro-4-(trifluoromethyl)phenyl)-7H-pyrrolo[2,3-C:5,4- C’] diisoxazoles from 2, 6- dichloro-4-trifluoro methyl aniline

Shankarsing Sardarsing Rajput*1, Rahebar Ali Mohammed Ali Sayyed2 1Department of Chemistry, SVS’s Dadasaheb Rawal College Dondaicha, Dist.Dhule, (M.S) 425408, India 2Department of Chemistry, PSGVPM’s Arts, Commerce and Science College, Shahada, Dist. Nandurbar (M.S) 425409, India A B S T R A C T The five membered cyclic imide derivative of 2, 6 dichloro-4-trifluoromethyl aniline was synthesized by reacting succinic anhydride ... Read More »

A New Validated Stability indicating RP-HPLC Method for the Quantitative Analysis of Phentermine Hydrochloride in Tablet Dosage Form

K.V. Lalitha*1, R. Kiranjyothi2 1Department of Pharmaceutical Analysis, Raghavendra Institute of Pharmaceutical Education and Research, Ananthapuramu – 515001, Andhra Pradesh, India. 2Department of Pharmaceutical Analysis, JNTUA – Oil Technological Research Institute, Ananthapuramu – 515001, Andhra Pradesh, India. A B S T R A C T A novel stability indicating RP-HPLC method was developed for the estimation of Phentermine hydrochloride in ... Read More »

A Comprahensive Review on Nanotechnology

Khaji Mohammad Anees1, Ch. Lalitha2*, Angilicam Avinash3, Dr. M. Sreenivasulu4 1B.Pharm 4th Year, Narayana Pharmacy College, Chinthareddy Palem, Nellore, A.P, India. 2Assistant Professor, Dept. of Pharmaceutical Chemistry, Narayana Pharmacy College, Nellore, A. P, India. 3Assistant Professor, Dept. of Pharmaceutics, Narayana Pharmacy College, Nellore, A. P, India. 4Principal, Narayana Pharmacy College, Chinthareddypalem, Nellore, Andhra Pradesh, India. A B S T R ... Read More »

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