Monday , 29 April 2024

Category Archives: Analytical Chemistry and New Analytical Methods

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Direct and Derivative Spectrophotometric Estimation of Moxifloxacin Hydrochloride by Chelation with Ruthenium (Ru III) Ions

Madhuri.D1*, Chandrasekhar K.B2, Devanna N3, Somasekhar G4  1Department of Pharmaceutical Analysis, Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, A.P, India 2Director & Professor, OTPRI-JNTUA, Anantapur, Andhra Pradesh, India-515002 3Professor, Department of Chemistry, JNT University, Anantapur, Andhra Pradesh, India-515002 4Department of Pharmaceutical Chemistry, Safa College of Pharmacy. Kurnool, Andhra Pradesh, India  A B S T R A C T A ... Read More »

Analytical Method Development and Validation by RP-HPLC Method in Bulk and Tablet Dosage form of Tacrolimus and Guggulsterone

Ramesh Dhani*, M. Gobinath, Sonalika Patro, T. Lavanya, A. Rajesh, G. Divya, C. Yamini, R. Pravallika Ratnam Institute of Pharmacy, Pidathapolur, SPSR Nellore, Andhra Pradesh, India. A B S T R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation of tacrolimus and guggulsterone was done by RP-HPLC. Present ... Read More »

Analytical Method Development and Validation for the Estimation of Betahistine HCL by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

B. Karuna Devi1, G. Sravan Reddy2, SK. Madeesh*3, V. Raja Kumar4, Ramanjineyulu Gunji5 1Malla Reddy College of Pharmacy, Maisammaguda, Dhulapally, Kompally, Medchal, Hyderabad-500014 2CEO, KP Technologies, Kothapet, Hyderabad- 500035 3Manager, Analytical Research and Development, KP Labs, Kothapet, Hyderabad- 500035 4St. John S College of Pharmacy, Yellapur, Hasanparthy, Warangal 3Research Associate, Analytical Research and Development, KP Labs, Kothapet, Hyderabad- 500035 A ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Acyclovir and Hydrocortisone by RP-HPLC Method in Bulk and Tablet Dosage Form

CH. Shankar*, B. Rajesh Department of Pharmaceutical Analysis, Vikas College of Pharmaceutical Sciences, Rayanigudem, Suryapet, Nalgonda, Telangana, India-508376 A B S T R A C T The chromatographic conditions were successfully developed for the separation of Acyclovir and Hydrocortisone by using Agilent C18  Column (250mm x 4.6mm)5µm, flow rate was 1ml/min, mobile phase ratio was  Phosphate buffer PH 2.5:Methanol (65:35 ... Read More »

Formulation Development and In-Vitro Evaluation of Mucoadhesive Buccal Tablets of Granisetron Hydrochloride

H. Padmalatha HOD, Pharmaceutical Analysis and QA, Gyana Jyothi College of Pharmacy, Boduppal, Hyderabad. A B S T R A C T The objective of this study was to develop effective mucoadhesive buccal tablets comprising of drug containing bioadhesive layer. Granisetron hydrochloride was formulated as buccal tablets to improve its bioavailability by avoiding first pass metabolism. HPMC K15M, HPMC K100M ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Brinzolamide and Timolol Maleate by RP-HPLC Method in Bulk and Tablet Dosage Form

CH. Shankar*, Punna Venkateshwarlu Department of Pharmaceutical Analysis, Vikas College of Pharmaceutical Sciences, Rayanigudem, Suryapet, Nalgonda, Telangana, India-508376 A B S T R A C T The chromatographic conditions were successfully developed for the separation of Brinzolamide and Timolol Maleate by using C18  Column (150mm x 4.6mm)5 µm, flow rate was 1 ml/min, mobile phase ratio was Methanol: Phosphate buffer ... Read More »

Desire and Characterization of Compression Coated Pulsatile Drug Delivery System of Doxofylline for the Treatment of Asthma

M. Divya1*, M. Kiranmai1, G. Vijaya Reddy1, G. Kalpana Devi2 1Sai Pranavi College of Pharmacy, Keesara, R.R. Dist., Telangana, India 2Assistant Professor, Sai Pranavi College of Pharmacy, Keesara, R.R. Dist., Telangana, India A B S T R A C T In the present research work sustained release matrix, formulation of Doxofylline targeted to colon by using various polymers developed. To ... Read More »

Formulation and In-Vitro Evaluation of Gastroretentive Floating Tablets of Hydrochlorthiazide

H. Padmalatha* HOD, Pharmaceutical analysis and QA, Gyana Jyothi College of Pharmacy, Boduppal, Hyderabad A B S T R A C T In the present research work gastro retentive floating matrix formulation of Hydrochlorthiazide by using various hydrophilic polymers. Initially analytical method development was done for the drug molecule. Absorption maxima was determined based on that calibration curve was developed ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Asparin and Atrovastatin Calcium in Combind Dosage Form by Using RP-HPLC Method

V. Aparna*, D. Sireesha, Dr. Vasudha bakshi Department of Pharmaceutical Analysis and Quality assurance, Anurag group of institutions (Formerly Lalitha college of pharmacy), Hyderabad, Telangana, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Aspirin   and Atorvastatin calcium in Tablet dosage form. Chromatogram was run through Agilent ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Metformine Hydrochloride and Pioglitazone by Using UV Spectrophotometry

N. Geetha*, D. Sireesha, Dr. Vasudha bakshi Department of Pharmaceutical Analysis and Quality assurance, Anurag group of institutions (Formerly Lalitha college of pharmacy), Hyderabad, Telangana, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformine hydrochloride and Pioglitazone in Tablet dosage form. Chromatogram was run through C18, ... Read More »

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