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Category Archives: Analytical Chemistry and New Analytical Methods

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Method Development and Validation for Simultaneous Estimation of Nifedipine and Triamterene by Using RP-HPLC in Bulk and Pharmaceutical Dosage Form

R. Sudheer kumar*, M. Gobinath, V. Haribaskar, Ramesh Dhani, V. Pavan kumar Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, Andhra Pradesh, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Nifedipine and Triamterene in Tablet dosage form. Chromatogram was run through Inertsil-ODS C18, 250x ... Read More »

Method Development and Validation by RP-HPLC for the Simultaneous Estimation of Telmisartin and Atorvastain in Tablet Dossage Form

Y. Vijitha*, V. Hari Baskar, M. Gobinath, Ramesh Dhani, V. Pavan Kumar, G. Varun Kumar Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India. A B S T R A C T A simple, sensitive and reproducible reverse-phase high performance liquid chromatographic (RP- HPLC) method has been developed for simultaneous quantitative estimation of Atorvastatin calcium ... Read More »

Design and In-Vitro Characterization of ORO Dispersible Tablets of Azithromycin

H. Padmalatha*  HOD, Pharmaceutical analysis and QA, Gyana Jyothi College of Pharmacy, Boduppal, Hyderabad. A B S T R A C T The goal of this project is to formulate Oro-dispersible tablet of Azithromycin that is intended to disintegrate rapidly into the oral cavity and form a stabilized dispersion. A direct compression method was failed to formulate dispersible tablet of ... Read More »

Design and Characterization of Chronotherapeutic Drug Delivery System of Dexibuprofen for the Treatment of Arthritis

Kishor*1, Bindu Madhavi2, K. Someshwar2 1Department of Pharmceutics, St. Pauls College of Pharmacy, Hyderabad, Telangana, India 2Manager, Formulation R&D, KP Labs (A Division of KDPL), Kothapet, Hyderabad Telangana, India A B S T R A C T In the present research work, chronotherapeutic drug delivery of Dexibuprofen was carried out. Chronotherapeutics refers to a treatment method in which in-vivo drug ... Read More »

Formulation Development and In -Vitro Evaluation of Bilayer Tablets Containing Dimenhydrinate and Cinnarizine

Kiran Kumar Yada1*, Dharmajit Pattanayak1, Saumya Das1, Vagdevi Y2 1Associate Professor, Vikas college of pharmaceutical sciences, Rayanigudem, Suryapet. 2Research Assistant, KP Labs, Kothapet (A Division of KDPL), Hyderabad. A B S T R A C T The conclusions  arrived  in  this  thesis  indicated  that  the  formulations  of Dimenhydrinate sustained in  this  investigation  was  found  to  be  satisfactory  based  on  in-vitro  release  ... Read More »

A Review on Thyroid Disease

B. Kumar*, K. Durga Prasanna Roja,  M. Gobinath Department of Pharmacy Practice, Ratnam Institute of Pharmacy, Pidthapolur, Nellore. A B S T R A C T The thyroid gland is one of the largest endocrine gland and consists of two connected lobes. The thyroid gland is found in the neck, below the thyroid cartilage. It participates in these processes by producing thyroid hormones, the principal ones ... Read More »

Development and Validation of New UV Spectroscopic and HPLC Methods for the Estimation of Zidovudine in Bulk and Pharmaceutical Dosage Form

Telugu Naga Mohan, Shaik Mohammed Yusuf*, Seerla Eswaraiah, D. Chinna Raju, E. Vijay Kumar Srinivasa Institute of Pharmaceutical sciences, Proddatur, YSR Kadapa [Dist]. AP. India.  A B S T R A C T In the present work, two simple, sensitive and specific methods (UV Spectroscopy and RP-HPLC) have been developed for the quantitative estimation of Zidovudine in bulk and pharmaceutical ... Read More »

Simultaneous Estimation Amitriptyline Hydrochloride and Chlordiazepoxide by HPLC Method

Seerla Eswaraiah, Shaik Mohammed Yusuf*, T. Naga Mohan, D. Chinna Raju, E. Vijay Kumar Srinivasa Institute of Pharmaceutical Sciences, Proddatur, YSR Kadapa, A.P. India A B S T R A C T A simple, economic, selective, precise, and accurate Reverse Phase High Performance Liquid Chromatography method for analysis of Amitriptyline HCl & Chlordiazepoxide in tablet dosage form was developed and ... Read More »

Method Development and Validation by RP-HPLC for the Simultaneous Estimation of Cinacalcet and Maxacalcitol in Tablet Dosage Form

N. Usha*, M. Gobinath, V. Hari Baskar, Ramesh Dhani, A. Soniya Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, A.P, India.  A B S T R A C T A Simple, selective, accurate, precise and linear RP-HPLC method was developed subsequently validated for estimation of cinacalcet in bulk & tablet dosage form. Gradient elution at a ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Telmisartan and Hydrochlorothiazide by UV-Spectrophotometric Method in Bulk and Tablet Dosage Form

L. Kanaka Lakshmi*, S. Harshini, Dr. Vasudha Bakshi, D. Sireesha, Akiful Haque Deparment of Pharmaceutical Analysis, School of Pharmacy, Anurag Group of Institutions, Ghatkesar, Ranga Reddy, Telangana-501301, India.  A B S T R A C T The Spectroscopic method was successfully developed for the separation of Hydrochlorothiazide and Telmisartan by using as solvent methanol, detection wavelength were at 271nm and ... Read More »

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