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Subrahmanyam Lanka* 1, Vaikuntarao Lakinani1, Eswara Rao Bammidi1, Siva Rama Rao Kakani2 1Department of Chemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, India 2Noida Internatioanl University, NOIDA, U.P A B S T R A C T Thrust in the preparation of new heterocyclic molecules is increasing due to their proven significant biological activities. The paramount importance of heterocycles such as indoles ... Read More »
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Category Archives: Pharmaceutical Sciences and research inventions
In-vitro Assessment of Free Radical Scavenging Anti-Inflammatory Potential and Phytochemical Analysis of Ethyl Acetate Leaf Extract of Manilkara Zapota
K. Kamalakararao1, K. Krishna Chaitanya1, Y.N. Sastry1, Dr. Ch. Surekha1, Dr. S.B. Padal2, Dr. D. Govinda Rao1 1Department of Biochemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh, India 2Associate Professor, Department of Botany, Andhra University, Visakhapatnam, Andhra Pradesh, India A B S T R A C T Phytochemical analysis had become a vital aspect in screening of valuable phytoconstituents. ... Read More »
Development and Characterization of Bioadhesive Gel Incorporated Microencapsulated Ketorolac Tromethamine for Periodontal Therapy
P. Parveen*, Dr. A. Seetha Devi Department of pharmaceutics, Hindu College of Pharmacy, Amaravathi Road, Guntur-522002, Andhra Pradesh, India A B S T R A C T To develop and characterize bioadhesive gel incorporated Ketorolac tromethamine loaded microspheres in order to sustain, localize and target drug action in periodontal pockets for more than 6hrs. Ketorolac tromethamine loaded microspheres was prepared ... Read More »
Biochemical Evaluation of Ash Value of Some Medicinal Plants of Genus Terminalia (Combretaceae) of Marathwada Region in Maharashtra
1Kadam V.B, 1Salve S.B, 1Deore S.V, 2Medhane V. J and 3Gaikwad V.B 1P. G. Dept. of Botany & Research Centre, K.T.H.M. College, Nasik–422 002 2P. G. Dept. of Chemistry & Research Centre, K.T.H.M. College, Nasik – 422 002 3Director, B.C.U.D., Savitribai Phule Pune University, Pune, India A B S T R A C T The seasonal variation of total ash, ... Read More »
Formulation and Evaluation of Niosomes of Valacyclovir Hydrochloride
A. Ankarao, CH. Sowjanya*, Dr.A. Seetha Devi, V. Vasu Naik, A. Rajesh Department of Pharmaceutics, Hindu College of Pharmacy, Amaravathi Road, Guntur A B S T R A C T Valacyclovir hydrochloride niosomes were prepared by thin film hydration and ether injection process with different ratios of (1:2:2, 1:4:2) drug and and Span-80 ,span 20(Non-ionic surfactant) cholesterol. The niosomes prepared ... Read More »
Sodium hypophosphite catalyzed synthesis of bis (indolyl) methanes in aqueous medium
Rasokkiyam Elayarajaa,b and R. Joel Karunakaranb* aResearch and Development Centre, Orchid Chemicals and Pharmaceuticals Ltd., Shozhanganallur, Chennai-600119. India. bDepartment of Chemistry, Madras Christian College, Tambaram, Chennai-600059, India. A B S T R A C T A mild method of sodium hypophosphite catalyzed synthesis of bis(indolyl)methanes has been described. This electrophilic bisubstitution reaction between indole and aldehyde were carried out in ... Read More »
Formulation and Evaluation of Tranexamic Acid Sustained Release Tablets
B. Venkateswara Reddy*, A. Divyasri Department of Industrial Pharmacy, St.Paul’s College of Pharmacy, Turkayamjal (V), Hayathnagar (M), R.R.Dist-501510. A B S T R A C T The aim of the current investigation is to design oral sustained release tablets of Tranexamic acid a drug used for the treatment or prevention of menorrhagia, haemorrhage and various bleeding disorders. The tablets were ... Read More »
Mouth Dissolving Tablets of Meclizine Hydrochloride by using Super Disintegrants Formulation and In-Vitro Evaluation
Dr. R. Srinivasan, K. Vinod Kumar*, G. Lakshmana, D. Rajesh Kumar, K. Savinay Kumar Siddhartha Institute of Pharmaceutical Sciences, Jonnalagadda, Narsaraopet, Guntur, Andhra Pradesh, India. A B S T R A C T In the present work, an attempt has been made to develop fast disintegrating tablets of Meclizine HCl. New generation super disintegrates Explotab, Ion exchange resin Tulsion 334 ... Read More »
Formulation Development of Atenolol Bilayer Tablets and Their In-vitro Characterization
B. Venkateswara Reddy*, N. Gangadhar, K. Navaneetha Department of Industrial Pharmacy, St.Paul’s College of Pharmacy, Turkayamjal (V), Hayathnagar (M), R.R.Dist-501510. A B S T R A C T The objective of this study was to develop an optimized bilayer floating tablet (BFT) containing atenolol. The BFT contains two layers, an immediate release layer having the conventional dose of atenolol along ... Read More »
Formulation and Evaluation of Zolmitriptan Mucoadhesive Patches for Buccal Drug Delivery
Dr. R. Srinivasan, Sk. Shakir Ahmad*, D. SK. Sarma, M. Geetavani, D. Rajesh Kumar, N. Basha Siddhartha Institute of Pharmaceutical Sciences, Jonnalagadda, Narsaraopet, Guntur, Andhra Pradesh, India. A B S T R A C T The zolmitriptan is a serotonin (5-HT1) agonist used for the treatment of migraine with or without aura. In the present research work, zolmitriptan buccal patches were ... Read More »
