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U. Venkatesh1*, Sri Rama Radha1, P. Suresh1, G. Sravan Reddy2 1St John’s College of Pharmacy, Yemmiganur, Kurnool, Andhra Pradesh 2Hi-Q Herbals, Kothapet, Hyderabad, Telangana A B S T R A C T Diarrhoeal disease is often a leading source of mortality and morbidity, especially among children in developing countries causing a major healthcare problem. As per suggestion of WHO, treatment ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Stealth Liposome- A Novel Drug Delivery System
S. Charumathi*, B. Reddy Padmaja, Pavan Kumar .V, R. Charan, Dr. M. Niranjan Babu Department of Pharmaceutical Analysis, Seven Hills College of Pharmacy, Venkataramapuram, Tirupathi, A.P, India A B S T R A C T A liposome is spherical, self closed vesicles of colloidal dimensions, in which phospholipids bilayer sequester part of solvent, in which it freely float, in its ... Read More »
Nephro-protective Activity of Methanol Extract of “Cassia tora” Seeds in Cisplatin Induced Nephrtoxicity in Mice
Raghuram Akinapelli*1, S.N Sri Harsha1, D. Yashwanth Kumar2 Faculty of Pharmacy, PACIFIC University, Udaipur, Rajasthan, India A B S T R A C T Kidneys have sensitive tasks, especially when they deal with unwanted substances, which have to be cleared from the system, principally toxins. Kidneys play an important role in the regulation of our endocrine and acid-base balance, erythropoiesis ... Read More »
Effct of Mechanochemically Synthesized Copper (II) and Silver (I) Complexes with Cefuroxime on Some Cephalosporin Resistance Bacteria
N. P. Ndahi1, M.B. Fugu1, I. Waziri1 and Y. A. Geidam2 1Department of Chemistry, University of Maiduguri, Maiduguri, Borno State, Nigeria 2Department of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria A B S T R A C T Complexation plays a vital role in drug development as a means of modifying the pharmacological, toxicological and physico-chemical properties of ... Read More »
Synthesis and Antimicrobial Studies on New Substituted 1,3,4-Oxadiazole Derivatives
Jyothi N Rao*, Pooja and Royline Department of Postgraduate Studies and Research in Chemistry, St Aloysius College, Mangaluru, 575003, India. A B S T R A C T A mixture of hydrazide, substituted aromatic aldehyde and ceric ammonium nitrate in dichloromethane taken in a beaker. Structures of the compounds synthesized were confirmed by IR, 1HNMR and Mass spectroscopic analysis. The ... Read More »
Anticancer activity of Piperazine Propyl-4-Oxo-3,4-Dihydroquinazoline-2-Carboxylate Derivatives
A. Gopi Reddy1, V. Harinadha Babu1*, Y. Jaya Prakash Rao2 1Department of Pharmaceutical Chemistry, G. Pulla Reddy College of Pharmacy, Hyderabad. 2Department of Chemistry, Telangana University, Nizamabad, Telangana A B S T R A C T In this study, The synthesized piperazine propyl-4-oxo-3,4-dihydroquinazoline-2-carboxylate derivatives were screened for their in vitro anti proliferative activity in these four different human cancer cell ... Read More »
Antidermatophytic activity of alkaloid and saponin extracts from Cnidoscolus aconitifolius.
Basil Ita1*, Samuel Eduok2 1Department of Chemistry, University of Uyo, Uyo, Akwa Ibom State, Nigeria. 2Department of Microbiology, University of Uyo, Uyo, Akwa Ibom State, Nigeria. A B S T R A C T The antidermatophytic activity of saponin and alkaloid extracts from organs of Cnidoscolus aconitifolius against Trichophyton rubrum, Microsporum gypseum, Epidermophyton floccosum and Trichophyton interdigitale was studied by ... Read More »
Design and Development of Modified Release Solid Oral Dosage Form (Entacapone)
Dr. Hareesh Dara*, Dr. Ampati Srinivas, Meesa Rajendar St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana. A B S T R A C T The present research work focuses on design and development of modified Release solid oral dosage form.entacapone: based on assessment of various parameters, in vitro drug dissolution profile and drug kinetics, hf14 was found to be optimized ... Read More »
Assessment of Xenobiotic Toxicity by Laccase Enzyme from Pleurotus Fungi
aSarathi. R, bSuja. D⃰ , cL. Parimala a,bDepartment of Biochemistry, Annai Violet Arts & Science College, Chennai, India cDepartment of Chemistry, Annai Violet Arts & Science College, Chennai, India A B S T R A C T Most of the known laccases are of fungal origin, in particular from the white rot fungi (Pleurotus Fungi). These fungi secrete lignolytic enzymes, ... Read More »
Method Development and Validation of Mycophenolate Mofetil by RP-HPLC
Rubina Kauser, M. Mushraff Ali Khan, Airaj Mahajabeen, Farhana Shaheen, Salma Begum MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Reversed-phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the ... Read More »
