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Category Archives: Chemical Sciences and Chemical research

journal of medicinal chemistry,bioorganic and medicinal chemistry letters,medicinal chemistry research,medicinal chemistry book

Analytical Method Validation for Essay of Emitricitabine, Rilpevirene and Tenofovir Alfanamide by RP-HPLC

Vasini Revathi, M. Shymala* Department of Analysis, Joginapally B.R. Pharmacy College, Yenkapally, Moinabad, Hyderabad, Telangana-500075 A B S T R A C T A new, simple, precise, accurate and reproducible RP-HPLC method for Simultaneous estimation of Emtricitabine and Tenofovir and Rilpivirine in bulk and pharmaceutical formulations. Separation of Emtricitabine and Tenofovir and Rilpivirine was successfully achieved on a Inertsil ODS ... Read More »

Synthesis of Some Substituted Quinazoline Moieties: A Review

M. A. Hameed Sadiq1*, Shoaib Patel2, Amol S. Dighe1, Rashmi D. Wani2, Bhagyashree P. Gaikwad2, Prashant Katiyar2, Shriram H. Bairagi2 1Department of Pharmaceutical Chemistry, Pravara Rural College of Pharmacy, Loni, India- 413736. 2Department of Pharmaceutical Chemistry, Ideal College of Pharmacy & Research, Kalyan, India- 421306. A B S T R A C T Quinazoline is an aza derivative of the ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Enalapril Maleate and Metoprolol by RP-HPLC Method

Pakir Pranaya* Guru Nanak Institute of Pharmacy, Ibrahimpatnam, Rangareddy, Telangana, India.  A B S T R A C T The proposed HPLC method was found to be simple, specific, precise, accurate, rapid and economical for simultaneous estimation of Metoprolol and Enalapril Maleate in tablet dosage form. From literature review and solubility analysis initial chromatographic conditions Mobile phase ortho phosphoric acid ... Read More »

RP HPLC Method Development and Validation of Bicaultamide and Simvastatin in Bulk and Pharmaceutical Dosage Forms

C. Srinavya*1, P. Sowjanya2, Dr. Gampa Vijaya Kumar3 1,2KGR Institute of Technology and Management,   Rampally,   Kesara,   Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T A new method was established for simultaneous estimation of Bicalutamide and Simvastatin by RP-HPLC method.  The chromatographic ... Read More »

RP-HPLC Metthod Development and Vaidation for Velpatasvir and Voxilaprevir by Simulatneous Determination in Bulk and Their Pharamceutical Dosage Forms

MD. Abdul Sattar*, A. Suneetha Department of Pharmaceutical Analysis, Hindu college of Pharmacy, Amaravathi Road, Guntur-522002, A. P, India. A B S T R A C T Chromatography is the most powerful and versatile technique available to the modern analyst. In a single step process it can separate a mixture into its individual components and simultaneously provide a quantitative estimate ... Read More »

In-Silico Design & Lead Optimization of Pyrazolo Quinazolines Derivatives using Docking, Virtual Screening Techniques

T. Srivalli*1, Dr. R.Suthakaran2 1Research Scholar, Department of Pharmaceutical Chemistry, JNTU Hyderabad, Telanagana, India. 2Vijaya College of Pharmacy, Hayathnagar, Hyderabad, Telangana, India. A B S T R A C T The pyrazolo quinazolines ring systems bearing various substituents at the C-3 position are widely distributed in nature. Luteolin is a flavanoid derivative, has been reported to have anti cancer, anti ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Desloratadine and Montelukast by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Shaik Anwar, G. Somashekar* Department of Pharmaceutical Analysis, Safa College of Pharmacy, B. Thandrapadu, Kurnool, Andhra Pradesh, India A B S T R A C T A new, simple, precise, accurate and reproducible RP-HPLC method for Simultaneous estimation of Desloratadine and Montelukast in bulk and pharmaceutical formulations. Separation of Desloratadine and Montelukast was successfully achieved on a ECLEPSE XDB C8 ... Read More »

Method Development and Validation of Assay of Pyridoxine Hydrochloride and Doxylamine Succinate

S. Masoom Vali*, G. Somasekhar, Y. Suresh, Haniffa Bee S, K. Suresh Department of Pharmaceutical Analysis, SAFA College of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T A new method was established for simultaneous estimation of Pyridoxine hydrochloride and Doxylamine succinate by RP-HPLC method.  The chromatographic conditions were successfully developed for the separation of Pyridoxine ... Read More »

Method Development and Validation of Elabasvir and Grazoprevir by using RP-HPLC

Sri Mounika, M. Shymala* Department of Pharmaceutical Analysis, Joginapally B.R. Pharmacy College, Yenkapally, Hyderabad, Telangana–500075 A B S T R A C T A new method was established for simultaneous estimation of Elbasvir and Grazopravir by RP-HPLC method.  The chromatographic conditions were successfully developed for the separation of Elbasvir and Grazopravir by using Symmetry (4.6 x 250mm, 5mm), flow rate ... Read More »

Analytical Method Validation Report for Essay of Glycopyrrocate and Formoteral Fumerate by RP-HPLC

B. Ashwini, M. Shymala*, JVC Sharma Department of Pharmaceutical Analysis, Joginapally B.R. Pharmacy College, Yenkapally, Hyderabad, Telangana–500075 A B S T R A C T A new method was established for simultaneous estimation of Glycopyrrolate and Formoterol fumerate by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Glycopyrrolate and Formoterol fumerate by using Xterra C18 (4.6 ... Read More »

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