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Chaitramallu M*, Dakshayini C, Devaraju kesagodu Department of Chemistry, University of Mysore, Yuvaraja’s College, Mysore-570006, Karnataka, India. A B S T R A C T The new tetralone (7a‐e) were synthesized as analogues of podophyllotoxin. They were prepared using 1-bromo-3, 4, 5‐trimethoxybenzene and aldehyde derivatives by Grignard reaction which is condensed with diethyl succinate by means of potassium tert-butoxide in ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Synthesis of Thiazole Derivatives—A Review
Gobala Krishnan P*1, Gnana Prakash K2, Chandra Sekhar K.B3 1Department of Pharmaceutical Chemistry, Vagdevi college of Pharmacy and Research Centre, Brahmadevam, Muthukur, Nellore, Andhra Pradesh, India. 2Department of Pharmaceutics, P Rami Reddy Memorial college of Pharmacy, YSR District, A. P, India. 3Department of Pharmaceutical Chemistry, JNTUA–Oil Technological & Pharmaceutical Research Institute, Anantapuramu, Andhra Pradesh, India. A B S T R ... Read More »
Synthesis, Characterization of New Mercaptobenzoxazole Fused Mannich Bases for Anti-inflammatory and Antibacterial Activity
Kalyani1 G*, Bethi Srinivas2, Sastry3 K.V, Vijaya Kuchana1 K 1Department of Pharmaceutical Chemistry, TKR College of Pharmacy, Hyderabad 2Department of Pharmaceutical Chemistry, Talla Padmavathi college of pharmacy, Warangal. 3Department of Pharmaceutics, Alliance institute of pharmaceutical sciences, Hyderabad. A B S T R A C T Mercaptobenzoxazole is a heteroaromatic chemical compound from the class of Benzoxazoles. A new series of ... Read More »
Evaluation of Darunavir for Neuroprotective Activity in Alzheimer’s Disease
Y. Navya Reddya*, Nymisha Ya, K. Rekha Ranib, Kuruva Jyothirmaib, R. Mohana Priyac, R. Vadivelana, T. Spurthid aDept. of Pharmacology, JSS College of Pharmacy, Udhagamandalam, Tamilnadu, India -643001 bDept. of Pharmaceutics, CES College of Pharmacy, NH – 7, Chinnatekur, Kurnool, India – 518218. c Dept. of Pharmaceutical Chemistry, Dr. K .V Subbareddy Institute of Pharmacy, Kurnool, India – 518218. dDept. of ... Read More »
Anti-Bacterial Activity of Abutilon indicum leaf extracts by using various solvents
G. Madan Mohan*1, Sk. Salma2, A. Avinash3 1Department of Pharmaceutical Analysis, Acharya Nagarjuna University, Guntur- 522 510, A. P, India. 2Deptartment of Pharmaceutical Chemistry, Narayana Pharmacy College, Nellore-524002, A. P, India. 3Deptartment of Pharmaceutics, Narayana Pharmacy College, Nellore-524002, A.P, India. A B S T R A C T Abutilon indicum (Linn.) is a shrub distributed throughout India which belongs Malvaceae family. In ... Read More »
Comparative Study for the Analysis of Cefixime trihydrate and its Degraded Products by Two RP-HPLC methods, one its Official and the other Developed Validated Method
Elsadig H. Kh. Adam*1 and Abdalfatah M.Bashir2 1,2Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Riyadh, Al-kharj 11942, Saudi Arabia A B S T R A C T The aim of the present work was aimed to carry out comparative study between method (1) [official method (BP, 2017)] and method (2) [developed validated analytical method (Adam et ... Read More »
Formulation and Evaluation of Microemulsion Based Gel System for the Transdermal Delivery of Isradipine
Salma Begum, Dr T. Mamatha, Rubina Kauser, Farhana Shaheen, Airaj Mahajabeen MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Isradipine (ISDP) is an effective calcium channel blocker used in the treatment of hypertension. It undergoes extensive first pass metabolism and bioavailability through the oral route is only about 15 to 24%.The purpose ... Read More »
Samarium triflet: Sm(OTf)3 a simple and efficient catalyst for the synthesis of 1,4-dihydropyridine (Hantzsch pyridines)
M. Venkanna, Dr. B. Sammaiah, K. Srinuvasulu, Prof. R. Madhusudhan Raju* Department of Chemistry, Osmania University, Hyderabad-07, Telangana A B S T R A C T 1,4-Dihydropyridine synthesis has been carried out using Samarium triflet, as a catalyst. This protocol is applicable to a variety of aldehydes with β-ketoester and ammonium acetate to afford the corresponding Hantzsch pyridines in excellent ... Read More »
Spectroscopic Studies of Mixed-ligand Complexes of Divalent Metals with Sulpha drug and Heterocyclic compound
Spectroscopic Studies of Mixed-ligand Complexes of Divalent Metals with Sulpha drug and Heterocyclic compound 2Olanipekun, Oladapo T, 1*Adewoyin, Samuel A, 3Okediran, Olukemi A, 2Bolarinwa, Oladayo T 1Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria. 2Federal College of Education (SPECIAL), Department of Chemistry, School of Science, P.M.B. 1089, Oyo, Oyo State, Nigeria. 3Federal College of Education (SPECIAL), Department of Integrated ... Read More »
Analytical Method Development and Validation for Simultaneous Estimation of Cilnidipine and Telmisartan in Combined Tablet Dosage Form by Using RP-HPLC
R. Chandra Sekhar*, Prof. Ravindernath Post graduate student, University College of Technology, Osmania University, Hyderabad, Telangana, India. A B S T R A C T Objective: To develop and validate a suitable method for the simultaneous estimation of Cilnidipine and Telmisartan in Tablet dosage form by using RP-HPLC method. Methods: The chromatographic separation was performed on ZORBAX SB-PHENYL, 250X 4.6mm. ... Read More »
