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Category Archives: Analytical Chemistry and New Analytical Methods

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Second order derivative spectrophotometry for simultaneous determination of Hg(II) and Ti(IV) using 3,4-dihydroxybenzaldehyde isonicotinoylhydrazone (DHBINH)

Dr. Srinivas Jagarlapudi*, Dr. V. Suryanarayana Rao, A. Ravi Kumar, Panchumarthi Srinivas, CH. Sunil Babu Obvez Labs Pvt. Ltd.  Plot No. 22 & 23, ALEAP Industrial Area, Pragathi Nagar, Hyderabad, Telangana-500090, India. A B S T R A C T A second order derivative spectrophotometric method is developed for the simultaneous determination of mercury (II) and titanium (IV) using 3, ... Read More »

Analytical Method Development and Validation for the Estimation of Lacidipine in Bulk and Dosage Form by RP-HPLC

Dandu Girija1*, Akkimi Padma1, A. Thirupathireddy2, B. Venkateswara reddy3 1Assistant professor, Department of Pharmaceutical Analysis, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andha pradesh       pin -523370. 2Associate Professor, Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta(M), Prakasam(Dist) Andha pradesh  pin – 523370. 3Professor, Department of Pharmaceutics, Sankar Reddy Institute of Pharmaceutical sciences, Salakalveedu(v), Bestavaripeta (M), ... Read More »

Novel stability indicating RP-HPLC method for the determination of Ondansetron impurities in Ondansetron Injection

Dr. Srinivas Jagarlapudi*1, A. Ravi Kumar2, Panchumarthi Srinivas2, M. Raveendra Babu2, P. Ramyasree2 1Sri Krishnadevaraya University, Anatapuramu. Andhra Pradesh, India-515003. 2Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupathi, A. Ranganpet, Andhra Pradesh-517102.  A B S T R A C T The author developed a novel and unique RP-HPLC method for the determination of all the impurities of Ondansetron with ... Read More »

Analytical Method Development and Validation for Simultaneous Estimation of Pyrimethamine and Sulphadoxine in Pharmaceutical Dosage form by RP-HPLC

N. Kalpana Devi*1, Tirupathi Rao Velamala2, D.S.S.N.Neelima3 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3Vikas Institite of Pharmaceutical Sciences, Rajahmundary A B S T R A C T A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Sulphadoxine and Pyrimethamine, in its pure form as well as in ... Read More »

Formulation and Evaluation of Telmisartan Oral Films

S. Sai Vikas1*, M. Nirosha2, T. Pragna3, D. Shakeer4, L.Chandana5, D. Tarun6 Department of Pharmaceutics, JNTUA-Oil Technological & Pharmaceutical Research Institute, Ananthapuramu, AP, India. A B S T R A C T Fast disintegrating oral systems are designed to provide rapid onset of action within a minute without need of water, swallowing or chewing. Telmisartan is an anti-hypertensive agent which is ... Read More »

Experimental Evaluation of Anti-Epileptic Activity & In-vivo Antioxidant Activity of Aqueous Extract of Borassus Flabellifer Fruit Pulp in Albino Mice

N. Kalpana Devi1*, Chandrika Dontha2, D.S.S.N. Neelima3 1,2Teegala Krishna Reddy College of Pharmacy, Hyderabad, Telangana State 3Vikas Institite of Pharmaceutical Sciences, Rajahmundary A B S T R A C T The aqueous extract of Borassus flabellifer fruit pulp was tested for its anti-epileptic action at 200 mg/kg and 500 mg/kg using the standard drugs phenytoin (for MES) and valproic acid (for ... Read More »

Formulation and Evaluation of Floating and Mucoadhesive Tablet of Oral Hypoglycemic Drug Nateglinide

G. Jagadish*1, Dr. Anil Kumar Middha*2 1Research Scholar, Department of Pharmaceutics, OPJS University, Churu, Rajasthan 2Dr. Anil Kumar Middha, OPJS University, Churu, Rajasthan A B S T R A C T In the present research work gastro retentive mucoadhesive floating formulation of Nateglinide by using various hydrophilic polymers. Nateglinide is a drug for the treatment of type 2 diabetes. Initially analytical method development was done ... Read More »

Stability indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Metformin and Teneligliptin in Pharmaceutical Formulation

Ramesh Dhani*, V. Haribaskar, J. Priyanka Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India A B S T R A C T A simple, Accurate, precise method was developed for the simultaneous estimation of the Metformin and Teneligliptin in pharmaceutical dosage form. Chromatogram was run through ODS2 C 18 (4.6 x 200mm, 10.0µm)column.   Mobile phase containing ... Read More »

Research Article Phytochemical Screening and Acute Toxicity Study of Methanol extract of “Cassia tora” Seeds

Raghuram Akinapelli*1, S.N Sri Harsha1, D. Yashwanth Kumar2 Faculty of Pharmacy, PACIFIC University, Udaipur, Rajasthan, India A B S T R A C T Many plant species have been used by most ethnic groups for treating different disease conditions ranging from small infections to skin diseases, asthma, dysentery, malaria and other multiple indications. Herbal Medicine is usage of herbs for ... Read More »

Development and Validation of Analytical Method for the Estimation of Zaltoprofen Using RP- HPLC Method

Kumarraja Jayavarapu*, Dr. S. Parimalakrishnan, Dr. V. D Sundar Research Scholar, Department of Pharmacy, Annamalai University, Tamilnadu – 608002. A  B  S  T  R A C T A simple, sensitive, linear, precise and accurate RP – HPLC method for the estimation of Zaltoprofen was developed and validated. Zaltoprofen [(2RS)-2-(10-oxo-10,11-dihydrodibenzo[b,f]thiepin-2-yl)propionic acid] is a potent NSAID with powerful anti-inflammatory and analgesic effects ... Read More »

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