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Category Archives: Analytical Chemistry and New Analytical Methods

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Stability Indicating RP-HPLC Method for Simultaneous Estimation of Amitriptyline Hydrochloride and Pregabalin in Bulk and Pharmaceutical Dosage Form

K. Suma, Rameeja Pattan*, V. Hari Baskar, Ramesh Dhani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore. ABSTRACT A simple, accurate ,precise method was developed for the simultaneous estimation of the amitriptyline hydrochloride and pregabalin  in tablet dosage form .chromatogram was run through ODS (250MM 4.6mm,5µ).Mobile phase containing potassium dihydrogen ortho phosphate as buffer and acetonitrile  in the ... Read More »

Development and Validation of a New Method for the Simultaneous Estimation of Metformin and Linagliptin in Bulk and Dosage form by using UV–Spectrophotometry

M. Mallikarjuna*, C. Guru Sudhakar, K. Siva Shankar, SK. Abid, P. Rameeja Ratnam Institute of Pharmacy, Pidathapolur, Nellore, AP, India ABSTRACT A Simple, Determined, and precise method to develop a new quantitative simultaneous identification of metformin hydrochloride and Linagliptin in combined pharmaceutical dosage forms. This method was based on the based on the UV spectrophotometric method for the simultaneous estimation of ... Read More »

Simultaneous Estimation of UV Spectroscopy and Method Development and Validation for Lansoprazole and Domperidone by RP-HPLC

Sanju Srinivas1, Marium Nazneen2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana A B S T R A C T A new method was established for simultaneous estimation of Lansoprazole and Domperidone  by  RP-HPLC method.   The chromatographic conditions were  successfully developed  for  the  separation  of  Lansoprazole and Domperidone by using ... Read More »

Synthesis, Characterization and Antibacterial Activity of some 1,3- Benzthiazol-2-amine derivatives

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India. Abstract Benzothiazole is an aromatic heterocyclic compounds with the general formula C7H5NS which consists of 5 membered hetero cyclic 1, 3 thiazole ring fused to benzene. Benzothiazole is a simple analogues which play a major  role in research which has wide number of ... Read More »

RP-HPLC Method Development and Validation for Simultaenous Estimation of Montelukast and Fexofenadine Hydrochloride in Bulk and Pharmaceutical Dosage Form

L. Nikhil kumar*1, Chandan R.S2 1JSS Academy of Higher Education and Research, Mysore-570015, Karnataka, India. 2Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysore 570015 Karnataka, India. A B S T R A C T A new method was established for simultaneous estimation of Faxofenadine Hydrochloride Hydrochloride and Montelukast by RP-HPLC method.  The ... Read More »

Stability Indicating RP-HPLC Method Development and Validation for the Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Pharmaceutical Dosage Form

D. Hemalatha, G. Dharmamoorthy* Department of Pharmaceutical Analysis, Krishna Teja Pharmacy College, Tirupati-517506, A.P, India ABSTRACT A simple, Accurate, precise method was developed for the simultaneous estimation of the Ledipasvir and Sofosbuvir in bulk and its  Tablet dosage form. Chromatogram was run through Std Kromosil C18 (150 x 4.6 mm, 5m) column. Mobile phase containing Buffer 0.01N KH2PO4: Acetonitrile taken ... Read More »

Simultaneous Estimation Method Development and Validated on Timolol Maleate and Brimonidine Tartrate by Using HPLC

1N. Kalpana Devi*, 2Sindhu Priya Mattepalli, 3D. S.S.N. Neelima 1,2 Teegala Krishna Reddy College of Pharmacy, Hyderabad Telangana State 3Vikas Institite of Pharmaceutical Sciences – Rajahmundary ABSTRACT A rapid and precise reverse phase high performance liquid chromatographic method has been developed for the validated of Timolol Maleate and Brimonidine Tartrate, in its pure form as well as in tablet dosage ... Read More »

Development and Validation of RP HPLC Method for Simultaneous Estimation of Netupitant and Palonosetron in Pharmaceutical Dosage Form

Dr. Gampa Vijay Kumar1*, B. Sravanthi2, N. Gayathri Aparna3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India. A  B  S  T  R A C T On the basis of experimental results, ... Read More »

RP HPLC Method Development and Validation for Simultaneous Estimation of Atzanavir and Ritonavir in Pharmaceutical Dosage Forms

Dr. Gampa Vijay Kumar1*, B.Sravanthi2, K.Indhumathi3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A  B  S  T  R A C T A new method was established for simultaneous ... Read More »

A Stability Indicating RP-HPLC Method Development and Validation for Simultaneous Estimation of Montelukast and Fexofenadine Hydrochloride in Bulk and Pharmaceutical Dosage Form

Dr. Gampa Vijay Kumar1*, Dr. T. Rajesh2, Jaya Chandhra3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A  B  S  T  R A C T A new method was established for simultaneous estimation of Faxofenadine and Montelukast by RP-HPLC method.  The ... Read More »

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