Monday , 22 October 2018

Tag Archives: Validation

Analytical Method Development and Validation for the Determination of Brinzolamide and Brimonidine Using Reverse Phase HPLC Method in Bulk and Pharmaceutical Dosage Form

Dr R. Vani1*, Amena Samreen2, Humera Tabassum3, Dr M.sunitha4* 1Head of Department, Pharmaceutical Analysis and QA, Shadan Women’s College of Pharmacy, Hyderabad. 2Post-Graduate Student, Shadan Women’s College of Pharmacy, Hyderabad. 3Post-Graduate Student, Shadan Women’s College of Pharmacy, Hyderabad. 4Principal, Shadan Women’s College of Pharmacy, Hyderabad. ABSTRACT In RP-HPLC method, the conditions were optimized to obtain an adequate separation of eluted ... Read More »

Simultaneous Estimation of UV Spectroscopy and Method Development and Validation for Lansoprazole and Domperidone by RP-HPLC

Sanju Srinivas1, Marium Nazneen2 1Associate Professor Department of Pharmacy, Ganga Pharmacy College, Nizamabad, Telangana 2Department of Pharmaceutical Analysis, Ganga Pharmacy College, Nizamabad, Telangana ABSTRACT A new method was established for simultaneous estimation of Lansoprazole and Domperidone by RP-HPLC method. The chromatographic conditions were  successfully developed  for  the  separation  of  Lansoprazole and Domperidone by using Xterra C18 5µ m (4.6*250mm) column, ... Read More »

Analytical Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms by RP-HPLC

G. Madhavi1, S. Sravani1, G. Nikithareddy1, V. Mounika1, B. Divya1, M. Chaithanya*1, Bijjiga Sravanthi2 1Bojjam Narasimhulu Pharmacy College, Sayeedabad, Hyderabad, Telangana-500059. 2KP Labs, Kothapet, Hyderabad-500035 A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid Chromatographic Method for simultaneous estimation of Valsartan and Sacubitril in ... Read More »

Validation of Developed Analytical Method for Valsartan Floating Tablets by Reverse Phase High Performance Liquid Chromatography

C. Saravanan*1, M. Purushothaman2 1Sun Rise University, Alwar, Rajasthan – 301030, India 2Scient Institute of Pharmacy, Ibrahimpatnam, Ranga Reddy (Dt), Hyderabad, Talangana-501 506, India. A B S T R A C T Aim of the present investigation was to validate a new analytical, simple, sensitive, selective and precise High Performance Layer Chromatograpic (HPLC) method for the estimation of Valsartan in ... Read More »

Method Development and Validation of Omeprazole by RP-HPLC Method in Bulk and Its Pharmaceutical Dosage Form

Nagadani Kalyani*, R. Kiran Jyothi, Dr. K.B Chandra Sekhar Department of Pharmaceutical Analysis, JNTUA- Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515001, A. P, India A B S T R A C T Omeprazole is a proton pump inhibitor ﴾PPI﴿ and a potent inhibitor of gastric acidity which is mostly used in the therapy of gastroesophageal reflux and peptic ulcer disease. ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Tablets

P. Vamsi Reddy*1, V. Asha Ranjani2, R. Chandra Sekhar3, M. Shyam Sundar3 1Centre for Pharmaceutical Sciences, IST, JNTU, Hyderabad -500085 2MLR Institute of Pharmacy, Dundigal (v), Hyderabad-500043 3Department of Pharmaceutical analysis& Quality assurance, OU, Hyderabad-500007 A B S T R A C T The present paper describes a new, simple, precise, and accurate RP-HPLC method for simultaneous estimation of ledipasvir ... Read More »

Stability Indicating RP-HPLC Method for the Simultaneous Determination of Anti-Infectious Vials Containing Sulbactam and Ceftazidime in Pharmaceutical Dosage

L Kalyani1 and Chava Venkata N Rao2* 1Department of Chemistry, NRI Institute of Technology, Perecherla, Guntur, Andhra Pradesh 2Department of Chemistry, NRI Institute of Technology, Pothavarappadu, Andhra Pradesh A B S T R A C T A simple, accurate, rapid, and stability-indicating RP-HPLC method for a combination of Sulbactam and Ceftazidime has been developed and subsequently validated in commercial formulation ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Cefadroxil and Ambroxol Hydrochloride by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Devanapelly Shashikantha Rao* Lecturer, Department of Chemistry, C.K.M. Arts and Science College, Warangal- 506006, Andhra Pradesh, India Abstract A Simple and rapid stability indicating RP-HPLC method was developed for the simultaneous determination of Cefadroxil and Ambroxol in bulk and pharmaceutical dosage form. A chromatographic separation of the two drugs was achieved with a Symmetry C18 (4.6 × 250 mm, 5 μm partical size, make: Xterra) ... Read More »

Design, Development and Validation of Bioanalytical Methods for Pharmaceutical Formulations – Review

Subramani1, M. Purushothaman*2 1Alwar College of Pharmacy, Sun Rise University, Alwar, Rajasthan – 301030, India 2Vasavi Institute of Pharmaceutical Sciences, Kadapa-516247, India A B S T R A C T Any method developed for the analysis of analytes in biological fluids must yield consistent results despite the variations in conditions during the course of a project. An ideal bioanalytical method ... Read More »

Method Development and Validation of Paracetamol, Guaifenesin, Ambroxol Hydrochloride, Phenylephrine Hydrochloride and Chlorpheniramine Maleate in Bulk and Combined Dosage Form Using RP-HPLC Technique

Swapnil B. Deshmukh*, Vilas L Badgujar, Priyanka N Chhajed, Trupti C. Mahajan, Tanvirahmad J. Shaikh DCS’S A.R.A College of Pharmacy, Nagaon, Dhule A B S T R A C T An RP-HPLC method for the simultaneous determination of Paracetamol, Guaifenesin, Ambroxol hydrochloride, Phenylephrine hydrochloride and Chlorpheniramine maleate in tablets was developed and validated ® as per ICH and FDA guidelines. ... Read More »

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