Tuesday , 24 October 2017

Tag Archives: Method development

Development and Validation of a RP-HPLC Method for the Determination of Acyclovir in Transdermal Patches

R. Venu Priya1 and Vinesh Kumar2 1Research Scholar, Sun Rise University, Alwar, Rajasthan, India. 2Department of Pharmacy, Sun Rise University, Alwar, Rajasthan, India. A B S T R A C T The present report describes a rapid and sensitive High Pressure Liquid Chromatography (HPLC) method with UV detection to quantify acyclovir in transdermal patches. After sample preparation with diluent separation ... Read More »

Validation of Developed Analytical Method for Valsartan Floating Tablets by Reverse Phase High Performance Liquid Chromatography

C. Saravanan*1, M. Purushothaman2 1Sun Rise University, Alwar, Rajasthan – 301030, India 2Scient Institute of Pharmacy, Ibrahimpatnam, Ranga Reddy (Dt), Hyderabad, Talangana-501 506, India. A B S T R A C T Aim of the present investigation was to validate a new analytical, simple, sensitive, selective and precise High Performance Layer Chromatograpic (HPLC) method for the estimation of Valsartan in ... Read More »

Evaluation of Analgesic Activity and Anti-Epileptic Activity of Ether Leaf Extract of Guggul

K. N. S. Karthik, Konda Ravi Kumar* Department of Pharmaceutical Chemistry, Hindu college of Pharmacy, Amaravathi Road, Guntur. Andhra Pradesh, India. A B S T R A C T Commiphora mukul is a flowering plant in the family Burseraceae. It is a shrubor small tree, attaining maximum height of 4 m, with thin paper y bark and thorny branches. The ... Read More »

Method Development and Validation of Metformin in Pure and Its Tablet Dosage Form by using RP-HPLC

Dr. Hareesh Dara, Meesa Rajendar, Dr. D Siva Dinesh St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana, India A B S T R A C T High Performance Liquid Chromatography is now one of the most powerful tools in analytical chemistry. It has the ability to separate, identify, and quantitative the compounds that are present in any sample that can ... Read More »

RP-HPLC Method Development and Validation for Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Tablets

P. Vamsi Reddy*1, V. Asha Ranjani2, R. Chandra Sekhar3, M. Shyam Sundar3 1Centre for Pharmaceutical Sciences, IST, JNTU, Hyderabad -500085 2MLR Institute of Pharmacy, Dundigal (v), Hyderabad-500043 3Department of Pharmaceutical analysis& Quality assurance, OU, Hyderabad-500007 A B S T R A C T The present paper describes a new, simple, precise, and accurate RP-HPLC method for simultaneous estimation of ledipasvir ... Read More »

Design, Development and Validation of Bioanalytical Methods for Pharmaceutical Formulations – Review

Subramani1, M. Purushothaman*2 1Alwar College of Pharmacy, Sun Rise University, Alwar, Rajasthan – 301030, India 2Vasavi Institute of Pharmaceutical Sciences, Kadapa-516247, India A B S T R A C T Any method developed for the analysis of analytes in biological fluids must yield consistent results despite the variations in conditions during the course of a project. An ideal bioanalytical method ... Read More »

Method Development and Validation of Artemether and Lumifantrine by RP-HPLC

Farhana Shaheen*, Rubina Kauser, Salma Begum, Airaj Mahajabeen, Md Fasiuddin MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Introduction Reversed-phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the immobilized ... Read More »

A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms

Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »

Development and Validation of Stability Indicating RP-HPLC Method for Amoxicillin and Clavulanate Potassium Related Impurities in Pharmaceutical Dosage Forms

Konda Sidda Reddy*1, Ramamohana Reddy Maddike2, J Sreeramulu2 1Department of Chemistry, Rayalaseema University, Kurnool, Andhra Pradesh, India. 2Departments of Chemistry, Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India A B S T R A C T A simple, cost effective, stability indicating reversed-phase High Performance Liquid Chromatography method was developed for separation and quantification of seventeen specified known related impurities in ... Read More »

A Validated RP-HPLC Method Development and Validation for Sacubitril and Valsartan in Combine Pharmaceutical Dosage Forms

Sarada1, P. Sowjanya2, Dr. Gampa Vijaya Kumar*3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T The Present work was to develop a simple, fast, accurate, precise, reproducible, Reverse Phase High Performance Liquid ... Read More »

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