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B. Syed Salman*1, K. Faizun2 1Department of Pharmaceutics, Mahathi College of Pharmacy, Madanapalle, India. 2Department of Pharmaceutics, P. Rami Reddy Memorial College of Pharmacy, Kadapa, India. A B S T R A C T Developed the novel antibacterial drugs with improved efficacy by using different polymers. the formulation and evaluation of an ophthalmic delivery system of an antibacterial agent Fluconazole, based ... Read More »
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Category Archives: Chemical Sciences and Chemical research
Analytical Method Development and Vaidation for Velpatasvir and Sofosbuvir in combined Dosage Form by RP-HPLC
K.Nithiyananthan1*, K.V.S.Prasadarao2 1Research Scholar, Acharya Nagarjuna University, Guntur, Andhra Pradesh 522510. 2Principal, Rahul Institute of Pharmaceutical Sciences and Research, Chirala, Andhra Pradesh 523157. A B S T R A C T The estimation of Velpatasvir and Sofosbuvir was done by RP-HPLC. The Phosphate buffer was pH 3.0 and the mobile phase was optimized with consists of Methanol: Phosphate buffer mixed ... Read More »
Analytical Method Development and Validation For in Vinblastine and Vincristine Combine Dosage Forms by RP–HPLC Method
K.Nithiyananthan1*, K.V.S.Prasadarao2 1Research Scholar, Acharya Nagarjuna University, Guntur, Andhra Pradesh 522510. 2Principal, Rahul Institute of Pharmaceutical Science And Research, Chirala, Andhra Pradesh 523157. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Vinblastine and Vincristine by using XterraC185µm (4.6*250mm) column, flow rate was1ml/min, mobile phase ratio was Phosphate buffer (0.05M) pH4.6: ... Read More »
Analytical Method Development and Vaidation for Ombitasvir and Paritaprevir in Combined Dosage Form by RP-HPLC
K.Nithiyananthan1*, K.V.S.Prasadarao2 1Research Scholar, Acharya Nagarjuna University, Guntur, Andhra Pradesh 522510. 2Principal, Rahul Institute of Pharmaceutical Sciences And Research, Chirala, Andhra Pradesh 523157 A B S T R A C T Ombitasvir and Paritaprevir by using Thermosil C18 column (4.0×125mm) 5µ, flow rate was 1ml/min, mobile phase ratio was (70:30 v/v) methanol: Sodium acetate buffer pH 3 (pH was adjusted ... Read More »
Investigation of Cardiac Protective Activity of Methanolic Extracts of Garcinia Indica in Rats
Saini Supraja1, Dr. Nagaraju, M.Kulkarni2, Dr. Vijaya Kumar Gampa3* 1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2Asso. Professor, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T Atherosclerotic heart ... Read More »
Synthesis, Characterization and Biological Evaluation of 2-styrylchromone Derivatives
SK. Asma Thunnisa*, Bodapati Raju Department of Pharmaceutical Chemistry, Vikas College of Pharmacy, Visannapeta, Krishna-521215(Dt), A.P, India A B S T R A C T In this present study of the Design, Synthesis and molecular docking studies of 2-styrylchromone derivatives as novel antioxidant agents was considered chromone as basic fundamental pharmacophore in order to show antioxidant properties. We have performed ... Read More »
Evaluation of Phytochemical screening and in vitro Anti-inflammatory activity of Ethanolic extract of Jatrophagossypifolia Linn.
P. Sailaja* Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore -524 346 A B S T R A C T The present study was aimed to evaluate the phytochemical screening and in-vitro anti- inflammatory activity of ethanolic extract of Jatrophagossypifolia Linn. It reveals the presence of considerable amount of alkaloid, steroid, phenolic substances and vitamin C (Ascorbic ... Read More »
Development of Enhanced Site Specific Periodontal Drug Delivery Systems for Minocycline HCl and Ciprofloxacin Gels
Mukamalla Suresh1*, Rohit Saraswat School of Pharmacy, OPJS University, Churu, Rajasthan A B S T R A C T Ciprofloxacin hydrochloride, fluoroquinone antibiotic and Minocycline hydrochloride, tetracycline antibiotic that could be used in the treatment of periodontitis for localized therapy. The ciprofloxacin gel was formulated using biodegradable PVP, CMC (5%, 10%, 20%, 30% w/w) and poloxamer. The gel was evaluated ... Read More »
Development and Validation of Inductively Coupled Plasma Mass Spectrometry Method for Simultaneous Determination of TIN(SN) content in Excipients and Formulations
JagadeswaraRao K1,2, Murali Mohan SV 2and *Rama Rao Malla1 1Department of Biochemistry, Cancer Biology Lab, GIS, GITAM University, Visakhapatnam, India 2Analytical Research and development Department, Shilpa Medicwere Limited, India 3Department of Chemistry, GIS, GITAM University, Visakhapatnam, India A B S T R A C T The pharmaceutical formulation manufacturing process use some of polymers, which contains traces of inorganic elements ... Read More »
Design Formulation and Evaluation of Lansoprazole Mouth Dissolving Tablets
R. Kavitha*, C.S. Pasrameswari, B.V. Ramana, G. Nagarajan Dr. K.V. Subba Reddy Institute of Pharmacy, Kurnool, Andhra Pradesh, India-518218 A B S T R A C T The aim of the present work is to investigate the possibility of preparing mouth dissolving tablet containing Lansoprazole by direct compression method. Mouth dissolving tablets are innovative tablet technology where the dosage form ... Read More »
