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Category Archives: Analytical Chemistry and New Analytical Methods

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Analytical Method Development and Validation for the Simultaneous Estimation of Enalapril Maleate and Metoprolol by RP-HPLC Method

Pakir Pranaya* Guru Nanak Institute of Pharmacy, Ibrahimpatnam, Rangareddy, Telangana, India.  A B S T R A C T The proposed HPLC method was found to be simple, specific, precise, accurate, rapid and economical for simultaneous estimation of Metoprolol and Enalapril Maleate in tablet dosage form. From literature review and solubility analysis initial chromatographic conditions Mobile phase ortho phosphoric acid ... Read More »

RP HPLC Method Development and Validation of Bicaultamide and Simvastatin in Bulk and Pharmaceutical Dosage Forms

C. Srinavya*1, P. Sowjanya2, Dr. Gampa Vijaya Kumar3 1,2KGR Institute of Technology and Management,   Rampally,   Kesara,   Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T A new method was established for simultaneous estimation of Bicalutamide and Simvastatin by RP-HPLC method.  The chromatographic ... Read More »

RP-HPLC Metthod Development and Vaidation for Velpatasvir and Voxilaprevir by Simulatneous Determination in Bulk and Their Pharamceutical Dosage Forms

MD. Abdul Sattar*, A. Suneetha Department of Pharmaceutical Analysis, Hindu college of Pharmacy, Amaravathi Road, Guntur-522002, A. P, India. A B S T R A C T Chromatography is the most powerful and versatile technique available to the modern analyst. In a single step process it can separate a mixture into its individual components and simultaneously provide a quantitative estimate ... Read More »

In-Silico Design & Lead Optimization of Pyrazolo Quinazolines Derivatives using Docking, Virtual Screening Techniques

T. Srivalli*1, Dr. R.Suthakaran2 1Research Scholar, Department of Pharmaceutical Chemistry, JNTU Hyderabad, Telanagana, India. 2Vijaya College of Pharmacy, Hayathnagar, Hyderabad, Telangana, India. A B S T R A C T The pyrazolo quinazolines ring systems bearing various substituents at the C-3 position are widely distributed in nature. Luteolin is a flavanoid derivative, has been reported to have anti cancer, anti ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Desloratadine and Montelukast by RP-HPLC Method in Bulk and Pharmaceutical Dosage Form

Shaik Anwar, G. Somashekar* Department of Pharmaceutical Analysis, Safa College of Pharmacy, B. Thandrapadu, Kurnool, Andhra Pradesh, India A B S T R A C T A new, simple, precise, accurate and reproducible RP-HPLC method for Simultaneous estimation of Desloratadine and Montelukast in bulk and pharmaceutical formulations. Separation of Desloratadine and Montelukast was successfully achieved on a ECLEPSE XDB C8 ... Read More »

Method Development and Validation of Assay of Pyridoxine Hydrochloride and Doxylamine Succinate

S. Masoom Vali*, G. Somasekhar, Y. Suresh, Haniffa Bee S, K. Suresh Department of Pharmaceutical Analysis, SAFA College of Pharmacy, Kurnool, Andhra Pradesh, India A B S T R A C T A new method was established for simultaneous estimation of Pyridoxine hydrochloride and Doxylamine succinate by RP-HPLC method.  The chromatographic conditions were successfully developed for the separation of Pyridoxine ... Read More »

Method Development and Validation of Elabasvir and Grazoprevir by using RP-HPLC

Sri Mounika, M. Shymala* Department of Pharmaceutical Analysis, Joginapally B.R. Pharmacy College, Yenkapally, Hyderabad, Telangana–500075 A B S T R A C T A new method was established for simultaneous estimation of Elbasvir and Grazopravir by RP-HPLC method.  The chromatographic conditions were successfully developed for the separation of Elbasvir and Grazopravir by using Symmetry (4.6 x 250mm, 5mm), flow rate ... Read More »

Analytical Method Validation Report for Essay of Glycopyrrocate and Formoteral Fumerate by RP-HPLC

B. Ashwini, M. Shymala*, JVC Sharma Department of Pharmaceutical Analysis, Joginapally B.R. Pharmacy College, Yenkapally, Hyderabad, Telangana–500075 A B S T R A C T A new method was established for simultaneous estimation of Glycopyrrolate and Formoterol fumerate by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Glycopyrrolate and Formoterol fumerate by using Xterra C18 (4.6 ... Read More »

Anti diarrheal activity of ethsnolic extract of the Memcyclon Edule leaves in castor oil induced diarrhea model in mice

U. Venkatesh1*, Sri Rama Radha1, P. Suresh1, G. Sravan Reddy2 1St John’s College of Pharmacy, Yemmiganur, Kurnool, Andhra Pradesh 2Hi-Q Herbals, Kothapet, Hyderabad, Telangana A B S T R A C T Diarrhoeal disease is often a leading source of mortality and morbidity, especially among   children in developing countries causing a major healthcare problem. As per suggestion of WHO, treatment ... Read More »

Stealth Liposome- A Novel Drug Delivery System

S. Charumathi*, B. Reddy Padmaja, Pavan Kumar .V, R. Charan, Dr. M. Niranjan Babu Department of Pharmaceutical Analysis, Seven Hills College of Pharmacy, Venkataramapuram, Tirupathi, A.P, India A B S T R A C T A liposome is spherical, self closed vesicles of colloidal dimensions, in which phospholipids bilayer sequester part of solvent, in which it freely float, in its ... Read More »

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