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Rubina Kauser, M. Mushraff Ali Khan, Airaj Mahajabeen, Farhana Shaheen, Salma Begum MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Reversed-phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the ... Read More »
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Category Archives: Analytical Chemistry and New Analytical Methods
Method Development and Validation of Voglibose in pure and Pharmaceutical Dosage form by RP-HPLC
Jogu Anitha*, P. Sunitha, Vijaya Kuchana Department of Pharmaceutical Analysis, Teegala Krishna Reddy College of Pharmacy, Meerpet, Hyderbad. A B S T R A C T The chromatographic conditions were successfully developed for the separation of Voglibose by Deveosil ODS-HG-5 C18 (250×4.6mm, 5cm) column. Flow rate was 1ml/min, mobile phase ratio was 70:30% v/v Acetonitrile : Buffer, UV detection at ... Read More »
Method Development and Validation of Metformin in Pure and Its Tablet Dosage Form by using RP-HPLC
Dr. Hareesh Dara, Meesa Rajendar, Dr. D Siva Dinesh St John College of Pharmcy, Hasanparthy, Hanamkonda, Telangana, India A B S T R A C T High Performance Liquid Chromatography is now one of the most powerful tools in analytical chemistry. It has the ability to separate, identify, and quantitative the compounds that are present in any sample that can ... Read More »
RP-HPLC Method Development and Validation for Simultaneous Estimation of Ledipasvir and Sofosbuvir in Bulk and Tablets
P. Vamsi Reddy*1, V. Asha Ranjani2, R. Chandra Sekhar3, M. Shyam Sundar3 1Centre for Pharmaceutical Sciences, IST, JNTU, Hyderabad -500085 2MLR Institute of Pharmacy, Dundigal (v), Hyderabad-500043 3Department of Pharmaceutical analysis& Quality assurance, OU, Hyderabad-500007 A B S T R A C T The present paper describes a new, simple, precise, and accurate RP-HPLC method for simultaneous estimation of ledipasvir ... Read More »
Method Development and Validation of Olodaterol and Tiotropium by RP-HPLC Method
Farhana Shaheen*, Salma Begum, Rubina Kauser, Airaj Mahajabeen, MD Muzammil Hassan MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Reverse phase high-performance liquid chromatography (RP-HPLC) involves the separation of molecules on the basis of hydrophobicity. The separation depends on the hydrophobic binding of the solute molecule from the mobile phase to the ... Read More »
Evaluation of Darunavir for Neuroprotective Activity in Alzheimer’s Disease
Y. Navya Reddya*, Nymisha Ya, K. Rekha Ranib, Kuruva Jyothirmaib, R. Mohana Priyac, R. Vadivelana, T. Spurthid aDept. of Pharmacology, JSS College of Pharmacy, Udhagamandalam, Tamilnadu, India -643001 bDept. of Pharmaceutics, CES College of Pharmacy, NH – 7, Chinnatekur, Kurnool, India – 518218. c Dept. of Pharmaceutical Chemistry, Dr. K .V Subbareddy Institute of Pharmacy, Kurnool, India – 518218. dDept. of ... Read More »
Anti-Bacterial Activity of Abutilon indicum leaf extracts by using various solvents
G. Madan Mohan*1, Sk. Salma2, A. Avinash3 1Department of Pharmaceutical Analysis, Acharya Nagarjuna University, Guntur- 522 510, A. P, India. 2Deptartment of Pharmaceutical Chemistry, Narayana Pharmacy College, Nellore-524002, A. P, India. 3Deptartment of Pharmaceutics, Narayana Pharmacy College, Nellore-524002, A.P, India. A B S T R A C T Abutilon indicum (Linn.) is a shrub distributed throughout India which belongs Malvaceae family. In ... Read More »
Comparative Study for the Analysis of Cefixime trihydrate and its Degraded Products by Two RP-HPLC methods, one its Official and the other Developed Validated Method
Elsadig H. Kh. Adam*1 and Abdalfatah M.Bashir2 1,2Department of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam bin Abdulaziz University, Riyadh, Al-kharj 11942, Saudi Arabia A B S T R A C T The aim of the present work was aimed to carry out comparative study between method (1) [official method (BP, 2017)] and method (2) [developed validated analytical method (Adam et ... Read More »
Formulation and Evaluation of Microemulsion Based Gel System for the Transdermal Delivery of Isradipine
Salma Begum, Dr T. Mamatha, Rubina Kauser, Farhana Shaheen, Airaj Mahajabeen MRM College of Pharmacy, Chintapalliguda, Ibrahimpatnam, R.R District-501510 A B S T R A C T Isradipine (ISDP) is an effective calcium channel blocker used in the treatment of hypertension. It undergoes extensive first pass metabolism and bioavailability through the oral route is only about 15 to 24%.The purpose ... Read More »
Spectroscopic Studies of Mixed-ligand Complexes of Divalent Metals with Sulpha drug and Heterocyclic compound
Spectroscopic Studies of Mixed-ligand Complexes of Divalent Metals with Sulpha drug and Heterocyclic compound 2Olanipekun, Oladapo T, 1*Adewoyin, Samuel A, 3Okediran, Olukemi A, 2Bolarinwa, Oladayo T 1Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria. 2Federal College of Education (SPECIAL), Department of Chemistry, School of Science, P.M.B. 1089, Oyo, Oyo State, Nigeria. 3Federal College of Education (SPECIAL), Department of Integrated ... Read More »
