Shaik Mastan Vali*, E. Rajani, C. Madhavi Latha, Y. Prapurna Chandra
Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore-524 346
This study targets the chronic skin condition acne with the aim of formulating an effective and safe Polyherbal gel by using Vigna radiata and Aloe barbadensis. The ethanolic extract of Vigna radiata and collected Aloe barbadensis gel were incorporated in to optimized Carbopol gel base. The combination of these two herbal constituents may produce an effect to minimise the Acne problem. Antimicrobial study shows that there was no microbial contamination observed and it showed good zone of inhibition and in vivo skin irritation study results showed that there was no skin lesions like defatting of skin, adverse skin reactions, local systemic change. Overall, this study reports concluded that the formulation of polyherbal gel may offer an effective and safe dosage form which leads to patient adherence and compliance to the therapy.
Keywords: polyherbal gel, Vigna radiate, Aloe barbadensis