Wednesday , 19 June 2024

Antimicrobial and Antioxidant Free Radial Scavenging Activity of Bark and Stem of Bacopa Monnieri

Pigilam Sai Pallavi*, C. Madhavi Latha, Y. Prapurna Chandra
Department of Pharmacology, Ratnam Institute of Pharmacy, Pidathapolur (V&P), Muthukur (M), SPSR Nellore District – 524 346

A b s t r a c t
This study was carried out with an objective to investigate the antimicrobial and antioxidant free radical scavenging activity of bark and stem of Hiptage benghalensis. The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on gram positive and gram-negative bacterial strains. In the present study, the antimicrobial activity of ethanol extract of bark of Hiptage benghalensis was evaluated for potential antimicrobial activity against gram positive and gram-negative bacterial strains. The extract (50, 100, µg/ml) of Hiptage benghalensis were tested against the gram positive and gram- negative bacteria. Zone of inhibition of extracts were compared with that of different standards erythromycin, for gram positive bacteria and cephalosporins like cefadex for gram negative bacteria. The results showed that the remarkable inhibition of the bacterial growth was tested against the tested organisms. The phytochemical analysis of the plant were carried out. The aim of the study of antioxidant activity is to assess the free radical scavenging activity of hiptage benghalensis by phosphomolybdenum method.

Keywords: Hiptage benghalensis, phosphomolybdenum, cephalosporins, cefadex

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