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About author : Anup K. Chakraborty*, Umesh K. Patil Dept of Pharmaceutical Chemistry, School of Pharmacy & Research Centre, People’s University, Bhopal (M.P.), India *e-mail: [email protected] Abstract: Incretin hormones are defined as intestinal hormones released in response to nutrient ingestion, which potentiate the glucose-induced insulin response. In humans, the incretin effect is mainly caused by two peptide hormones, glucose-dependent insulin ... Read More »
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Category Archives: Chemical Sciences and Chemical research
IRON RICH FOOD TO ENRICH WOMEN
About author : Praveena S*, Dr. Hindustan Abdul Ahad Dept. of Pharmaceutical analysis, Balaji College of Pharmacy, AP, India *e-mail: [email protected] INTRODUCTION Iron is essential for life. Not only it is found in proteins and enzymes, but it is responsible for cell growth and transporting oxygen throughout the body. Excessive or insufficient amounts however, may result in serious health issues. ... Read More »
SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL SUBSTITUTED CHALCONE DERIVATIVES
About author: P. Sudheer Kumar Narayana Pharmacy College, A.P, India E-mail: [email protected] ABSTRACT: Chalcone is an aromatic ketone that forms the central core for the variety of important biological compounds, which are collectively known as chalcones. The name chalcones was given by Kostanecki and Tambor. The chalcones, two aromatic rings are linked by an aliphatic three carbon chain which bears ... Read More »
SYNTHESIS AND CHARACTERIZATION OF 2-MERCAPTOBENZIMIDAZOLE
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, India E-mail : [email protected] Abstract: Recently in benzimidazole chemistry has been revived somewhat by the discovery that the 5,6-dimethyl benzimidazole moiety is a part of the chemical structure of vitamin B12.The benzimidazoles are also known as benziminazolones or benzoglyoxalines.The new benzimidazole derivative i.e, 2-mercapto benzimidazole was synthesized.The melting point ... Read More »
ANTIMICROBIAL SCREENING OF SOME NOVEL SUBSTITUTED CHALCONE DERIVATIVES
About author : P. Sudheer Kumar Narayana Pharmacy College, A.P, India. E-mail: [email protected] ABSTRACT: Chalcone is an aromatic ketone that forms the central core for the variety of important biological compounds, which are collectively known as chalcones. The derivatives of chalcones with an annular nitrogen atom in the phenyl ring were reported to have a wide range of biologically activities, ... Read More »
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL SCREENING OF SOME NOVEL BENZOIN DERIVATIVES
About author: P. Deepthi Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur,India E-mail: [email protected] INTRODUCTION :A natural product is a chemical compound or substance produced by a living organism – found in nature that usually has a pharmacological or biological activity for use in pharmaceutical drug discovery, drug design. A natural product can be considered as such even if it ... Read More »
Synthesis and Characterization of 4-[2′-(5′-Nitro) Imidazolyl] Benzoyl(N-Me) Threonine
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, India E-mail: [email protected] ABSTRACT: Introduction of D-amino acids and N-methylation of amino acids like tyrosine, valine, alanine etc enhanced antimicrobial activity. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent biological activities. Many of the heterocyclic found ... Read More »
Synthesis and Characterization of 4-[2′-(5′-Nitro) Imidazolyl] Benzoyl (N-Me) Leucine
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: In the past two decades, a wide variety of bioactive peptides have been discovered. Many of the heterocyclic found to exhibit antifungal, antibacterial, cytotoxic, antineoplastic, insecticidal, anti-inflammatory, tyrosinase inhibitory and melanin production inhibitory activities. Imidazole has been drawn as promising structural units in the ... Read More »
Synthesis and characterization of 3-[(5-phenyl hydroxyl-1, 3, 4-oxadiazol-2-yl) methyl amino]-2-methyl quinazolin-4(3h)-one
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Quinazolinone is a heterocyclic compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, ... Read More »
SYNTHESIS AND CHARACTERIZATION OF 4-[2′-(5′-NITRO) IMIDAZOLYL] BENZOYL (N-ME) VALINE
About author : Ramesh Dhani Dept of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail : [email protected] ABSTRACT: Many of the heterocyclic found to exhibit antifungal, antibacterial, cytotoxic, antineoplastic, insecticidal, anti-inflammatory, tyrosinase inhibitory and melanin production inhibitory activities. Imidazole has been drawn as promising structural units in the field of medicinal chemistry. Introduction of D-amino acids and N-methylation of amino acids like ... Read More »
