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U. Srinivasulu*1, N. Devanna2, M.Suneetha3, B. Siva Sai Kiran3, S. Muneer3 1Associate Professor of Chemistry, SBSYM Degree College, Kurnool-518004, A.P., India 2Professor and Director, Department of Chemistry, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India. 3Department of Pharmaceutical Sciences, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India A B S T R A C T A simple, sensitive ... Read More »
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Category Archives: Analytical Chemistry and New Analytical Methods
Validation of HPLC Test Method For Methylcobalamin 1500mcg Tablets
Kalpana Patankar-Jain1, Parag Gadkari2, Pushkar Pradhan3 1Department of Chemistry, B. N. N. College, Bhiwandi 2Inventia Healthcare Pvt. Ltd., Thane 3Department of Chemistry, Ramnarain Ruia College, Mumbai A B S T R A C T The current research paper gives method validation report for the quantification of methylcobalamin tablets. The method involved an gradiensystem of Phosphate buffer pH 3.5 and acetonitrile. ... Read More »
Pharmacological Screening of Premna Latifolia against High Fructose Diet Induced Insulin Resistance, Hyperlipidemia and Obesity in Male Wistar Rats
Kongi Kavyasudha*, Mubarak Yagoub Bashar Abdelmoula, Ballavolu Sandeep Sree Venkateswara University, Tirupati. ABSTRACT Insulin is a natural hormone made by the pancreas that controls the level of the sugar glucose in the blood. Insulin permits cells to use glucose for energy. Cells cannot utilize glucose without insulin. Insulin stops the use of fat as an energy source by inhibiting the ... Read More »
Analytical Method Development and Validation for Pirfenidone (Anti-Fibrotic) in bulk drug and dosage form
Katikala Dharmendra*, Dr. C. Sreedhar, T. Sreenivasa Rao, Rikshaya Tamang, Meghnath Chaudhary, Mohamed adam Department of Pharmaceutical Analysis, Karnataka College of Pharmacy, #33/2,Thirumenahalli,Hegde Nagar main road, Bangalore – 560064, KA. India. A B S T R A C T Pirfenidone, 5-methyl-1-phenyl-2-(1H)-pyridine is a novel Anti-fibrotic agent approved for mild to moderate Idiopathic pulmonary fibrosis (IPF). Isocratic reverse phase high performance ... Read More »
Pharmacological Evaluation of Antidepressant Activity of Piper Betel Leaves and Clove
Shaik Salmasultana*, P. Sukumari, SK. Shafi, D. Maheswari, P. Ramsai, K. Sasikumar, A. Sravani Department of Pharmacology, Jagan’s Collegeofpharmacy, Gangalakandriga, Nellore A B S T R A C T The antidepressant activity of eugenol excluded clove extract was investigated using two different models of stress induced depression (forced swim test and Tail suspension method). Animals were divided into different groups each ... Read More »
Method Development and Validation of Sofosbuvir and Ledipasvir in API & Its Pharmaceutical dosage forms by RP-HPLC
Shinnde Sandeep* Department of Pharmaceutical Analysis & Quality Assurance ,SSJ College of Pharmacy,Vattinagulapally, Gandipet, Hyderabad – 500075, Telangana State A B S T R A C T Ledipasvir is indicated in patients with hepatitis C virus (HCV) genotype 1 for treatment of chronic hepatitis as a combination therapy, which includes peg interferonalfa and ribavirin. Ledipasvir is a protease inhibitor for ... Read More »
Synthesis and antimicrobial activity of Schiff base of quinolene-2-ones
Dr. Alka Pradhan and Sanjay Kumar Vishwakarma* Professor, Department of Chemistry, S. N. Govt. G.P.G. College Bhopal. *Research Scholar, Department of Chemistry, S .N. Govt. G.P.G. College Bhopal. A B S T R A C T In the present study, we synthesized Schiff bases of quinolene-2-one and their antibacterial activity was evaluated by wells diffusion method. Schiff bases of quinolene-2-one ... Read More »
Development and Validation of new UV-Visible Spectrophotometric Method for the Estimation of Losartan in Tablet Dosage Form
*Suruchi Samparna Acharya, R. Maneesha, L. Manikanta, M. Ajay Kumar, P. Gowthami, B. Hareesh Jagan’s College of Pharmacy, Jangala Kandriga (V), Muthukuru (M), Nellore, Andhra Pradesh, India. A B S T R A C T A simple, Accurate, precise method was developed for the estimation of Losartan in Tablet dosage form. Solutions of Losartan were prepared in solvent like methanol ... Read More »
Development of Validated Stability Indicating Assay Method by RP-HPLC for Simultaneous Estimation of Azilsartan Medoximil and Chlorthalidone in Their Bulk and Combination Form
S. Priyanka Yadav*1, P. Sowjanya2, Dr. Gampa Vijaya Kumar3 1,2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India, 3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India A B S T R A C T Method was established for simultaneous estimation of Azilsartan medoxomil and Chlorthalidone by RP-HPLC method. The ... Read More »
Development and Validation of Stability Indicating RP-HPLC Method for the Simultaneous Estimation of Torsemide and Spiranolactone in Bulk Drug and Pharmaceutical Dosage Form
V. Haribaskar, Ramesh Dhani, B. Swathi* Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore, A.P, India A B S T R A C T Simple precise and accurate method was developed for the estimation of Torsemide and Spiranolactone. The mobile phase consisting 20% Buffer: 80%ACN. The column was used: Inertsil ODS 4.6*210mm, 5µ with flow rate 1ml/min using ... Read More »
