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Category Archives: Analytical Chemistry and New Analytical Methods

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RP-HPLC Method Development and Validation for the Simultaneous Estimation of Spironolactone and Furosemide in Bulk and Pharmaceutical Dosage Form

Dr. GampaVijayKumar1*, Dr.D.Naresh2, N. Krishna Nayak3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India.  A B S T R A C T High performance liquid chromatography is at present one of ... Read More »

Analytical Method Development and Validation for Lamivudine and Zidovudine Combine Pharmaceutical Dosage Forms by RP-HPLC

Dr.  Gampa Vijay Kumar1*, Dr. T. Rajesh2, C. Mounika3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.                                                                                              2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana,India. A B S T R A C T A new method was established for ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Saxagliptin and Dapagliflozin in Pharmaceutical Dosage Form

Prathap.B1*, Haribaskar.V2, Kumar.B3, Ramesh Dhani4, Bhavya.CH5, Kavitha.M6, Harika.S7 Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Nellore – 524346, Andhra Pradesh, India.  A B S T R A C T A simple, sensitive, accurate, precise and stability indicating RP-HPLC method has been developed for the simultaneous estimation of saxagliptin and dapagliflozin in combined pharmaceutical dosage form. The analysis was carried ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Amlodipine and Benazepril In Bulk and Pharmaceutical Dosage Form

Mannepalli Mounika, V. Haribaskar*, B. Prathap, Ramesh Dhani Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Nellore  A B S T R A C T A simple, Accurate, rapid and precise method was developed for the simultaneous estimation of the Amlodipine and Benazepril in Tablet dosage form. The chromatogram was run through Inertsil ODS (4.6 x 100mm, 5µm). Mobile ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Buprenorphine and Naloxone by RP- HPLC Method

D. Vijaya Durga1*, V. Gunasekaran2 1Department of Pharmaceutical Analysis & Quality Assurance, Rao’s College of Pharmacy, Chemudugunta, Nellore-524320 2Department of Pharmaceutical Chemistry, Rao’s College of Pharmacy, Chemudugunta, Nellore-524320 A B S T R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation of Buprenorphine and Naloxone was done ... Read More »

A Novel Analytical Method Development and Validation of Tiotropium Bromide and Formoterol Fumarate Pharmaceutical Dosage Forms by using RP-HPLC Method

S. Priyanka, M. Anuradha, Kavita Waghray Department of Pharmacy, University College of Technology, Osmania University,Hyderabad-500007, Telangana, India A B S T R A C T High performance liquid chromatography is at present one of the most sophisticated tool of the analysis. The estimation of Tiotropium Bromide and Formoterol Fumarate was done by RP-HPLC Method. Separation was achieved under optimized chromatographic condition ... Read More »

Preparation, Phytochemical Analysis and Pharmacological Evaluation of Antiepileptic and Anti-Oxidant Activity of Ethanolic Seed Extract of Caesalpinia Crista in Rats

Shaik Reshma1*, P. Pandu1, Dr. N. Srinivasa Rao2, M. Sreekanth3 1Department of Pharmacology, Vikas College of Pharmacy, Vissannapeta, Krishna (Dt)-521215, Andhra Pradesh, India 2Principal, Department of Pharmaceutical Analysis and Quality Assurance, Vikas College of Pharmacy, Vissannapeta, Krishna (Dt)-521215, Andhra Pradesh, India. 3Research Scholar, Pharmaceutical Sciences, Ratnam Institute of Pharamacy, Pidathapolur, Nellore, Andhra Pradesh A B S T R A C ... Read More »

RP-HPLC Method Development and Validation for the Simultaneous Estimation of Donepezil and Memantine in Pure and Pharmaceutical Dosage Form

Dr. Gampa Vijay Kumar*1, Dr. D. Naresh2, M.Kirthi3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2,3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T On the basis of experimental results, the proposed method is suitable for the quantitative determination of ... Read More »

Analytical Method Development and Validation for Ivermectin and Albendazole in Combine Dosage Form by RP-HPLC

Dr. Gampa Vijay Kumar 1*, B. Sravanthi 2, A. Praveen3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2,3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T New method was established for simultaneous estimation of Ivermectin and Albendazole by RP-HPLC method. ... Read More »

Analytical Method Development for Simultaneous Estimation of Brimonidine and Brinzolamide by Using RP-HPLC

Dr. Gampa Vijay Kumar*1, K. Mahitha2 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T In RP-HPLC method, the conditions were optimized to obtain an adequate separation of eluted compounds. Initially, various mobile ... Read More »

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