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Category Archives: Analytical Chemistry and New Analytical Methods

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Method Development and Validation of Brinzolamide and Brimonidine In Its Bulk And Ophthalmic Dosage Form By Using RP-HPLC

Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, R.Hema3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. A B ... Read More »

Analytical Method Development and Validation for the Simultaneous Estimation of Empagliflozin and Linagliptin In Pharmaceutical Dosage Forms By RP-HPLC Method

Dr.K.Nageswara Rao1*, Raghava Doonaboyina2, S.Rajesh3 1Professor and Head, Dept. of Pharmaceutical Analysis, K.G.R.L College  of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Dept. of Pharmaceutical Chemistry, K.G.R.L College  of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College  of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. A B S T ... Read More »

Validation of HPLC Method of Aceclofenac and Rabeprazole Sodiumin Aceclofenac Sustained Release and Enteric Coatedrabeprazole Sodium Capsules

Kalpana Patankar-Jain1, Parag Gadkari2, Pushkar Pradhan3 1Department of Chemistry, B. N. N. College, Bhiwandi 2Inventia Healthcare Pvt. Ltd., Thane 3Department of Chemistry, Ramnarain Ruia College, Mumbai A B S T R A C T The current research paper gives method validation report for the simultaneous quantification of Aceclofenac Sustained Release 200mg and Enteric Coated Rabeprazole 20mg capsules. The method involved ... Read More »

Develop and Validate a Method for the Estimation of Marbofloxacin in Pure and Pharmaceutical Dosage Form by Photo Fluorimetry

D. Chinababu*, C. Madhusudhana chetty, B. Vamsi Krishna, D. Hemanth kumar, N. Srikanth, P. Santhi, G.V. Prasanthi Santhiram College of Pharmacy, Nandyal, Kurnool District, A.P. India. A B S T R A C T A simple and sensitive spectro fluorometric method was developed for the determination of Marbofloxacin in pure and its pharmaceutical dosage forms. The method is based on the ... Read More »

Simultaneous Estimation of Neutipotent and Palonesetron in Its Bulk and Pharmaceutical Dosage Form by RP-HPLC Method

Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, M. Jayasri3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. A ... Read More »

Analytical Method Development and Validation For the Simultaneous Estimation of Buprenorphine and Naloxone By RP- HPLC Method

Dr. K. Nageswara Rao1*, Raghava Doonaboyina2, Bhavani3 1Professor and Head, Department of Pharmaceutical Analysis, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 2Associate Professor and Head, Department of Pharmaceutical Chemistry, K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. 3K.G.R.L College of Pharmacy, KGRL Road, Bhimavaram, West Godavari, Andhra Pradesh, India. A B ... Read More »

Stability Indicating RP-HPLC Method for Simultaneous Estimation of Lumacaftor and Ivacaftor in Bulk and Pharmaceutical Dosage Forms

Rameeja Pattan*, V. Haribaskar, Pasala Sandhya Mounika, Ramesh Dhani, B. Prathap Department of Pharmaceutical Analysis, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, Nellore A B S T R A C T A simple, fast, accurate, precise, reproducible Stability indicating Reverse phase High performance liquid chromatography (RP-HPLC) method was developed and validated for the determination of Lumacaftor and Ivacaftor in Bulk and ... Read More »

Method Development and Validation of Acetazolamide Single Drug Molecule by Using UV Double Beam Spectrophotometer

Rameeja Pattan*, M. Charitha, M. Hemalatha, C. Lalitha, P. Pravallika, M. Vyshnavi, V. Sneha Priya Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore-524 346, Andhra Pradesh A B S T R A C T This UV-spectrophotometric technique is quite simple, accurate, precise, reproducible, and sensitive. The UV method has been developed for quantification of Acetazolamide in tablet formulation. The validation ... Read More »

A Novel RP-HPLC Method Development and Validation for the Estimation of Pyrimethamine in Bulk and its Pharmaceutical Formulation

U. Srinivasulu*1, N. Devanna2, A. Sandhya 3, B. Siva Sai Kiran3, S. Muneer3 1Associate Professor of Chemistry, SBSYM Degree College, Kurnool-518004, A.P., India 2Professor and Director, Department of Chemistry, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India. 3Department of Pharmaceutical Sciences, JNTUA-Oil Technological and Pharmaceutical Research Institute, Ananthapuramu-515002, A.P., India A B S T R A C T A simple, ... Read More »

Simultaneous Estimation of Moxonidine and Hydrochlorothiazide in Tablets by RP-HPLC

A. Thenmozhi, H. Mubeena*, N. Venkateshan Department of Pharmaceutical Analysis, Arulmigu Kalasalingam College of Pharmacy, Anand Nagar, Krishnankoil -626 190, Tamil Nadu. A  B  S  T  R  A  C  T A simple, precise, specific sensitive and accurate reverse phase high performance liquid chromatographic (HPLC) method was developed for the determination of Moxonidine and Hydrochlorothiazide in tablet dosage form. The separation ... Read More »

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