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Shivani Sutar* Department of Pharmacology, PES University, 100 Feet Ring Road, Banashankari, Bengaluru, Karnataka-560085. A B S T R A C T Naringi crenulata (NC) leaves have demonstrated different properties of nervous system. However, the leaves have not still studied to treat epilepsy. The aim of the present study was to determine the effect of NC hydroalcoholic extract on MES ... Read More »
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Development and validation of a Sensitive Bio analytical method for the quantitative estimation of Desvenlafaxine in human plasma samples by LC–MS/MS: Application to bioequivalence study
Narendra Kumar Reddy Kolli*1, Swetha Polagani1, Bharghava Bhushana Rao Pathange2 1Sri Vani School of Pharmacy, Chevuturu, Vijayawada, AP. India. 2VVIPS, Gudlavalleru, Krishna Dt, AP, India A B S T R A C T A Novel sensitive and selective ultra-high performance liquid chromatography-coupled to mass spectroscopy (LCMS/MS) method was developed and validated for the quantification of Desvenlafaxine in human plasma ,when ... Read More »
A Systematic Review of Desvenlafaxine’s Efficacy, Safety, Moa, and Adverse Effects in the Treatment of Major Depressive Disorders
Narendra Kumar Reddy Kolli*1, Swetha Polagani1, Bharghava Bhushana Rao Pathange2 1Sri Vani School of Pharmacy, Chevuturu, Vijayawada, AP. India 2VVIPS, Gudlavalleru, Krishna Dt, AP, India A B S T R A C T Desvenlafaxine (DVS) was a novel serotonin (5-HT) that was currently in clinical development for the treatment of major depressive disorder and vasomotor symptoms associated with menopause. Desvenlafaxine ... Read More »
A Study on Regulatory Guidelines for Product Development in Clinical Trial Research Studies in India, USA, AUSTRALIA
Eppalapalli Sree Rani1, K. Sunil Kumar*2 1Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. 2Associate Professor, Department of Pharmaceutics – Drug regulatory affairs, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India A B S T R A C T Drug discovery has a long history and dates back to the early days ... Read More »
Preparation and Evaluation of Polyherbal Anti Diabetic Formulation
K. Sunil Kumar1, R. Vengamma2 1Associate Professor, Department of Pharmaceutics, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. 2Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. A b s t r a c t The aim of this study is to develop and evaluate antidiabetic polyherbal capsules containing multiple plant extracts. Utilizing ... Read More »
Preparation and Characterization of Paclitaxel Nanoparticle by Precipitation Technique
K. Sunil Kumar1, C. Nazeer2, V. Vanisree3, P. Ramya4, R. Latha5, C. Sisindra6 1Associate Professor, Department of Pharmaceutics, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. 2,3,4,5,6Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. A b s t r a c t Paclitaxel is a microtubule-stabilizing agent which promotes polymerization of tubululin ... Read More »
RP-HPLC method development and validation for estimation of voriconazole, azithromycin and metoprolol tartrate in pharmaceutical dosage form
K. Dileep*1, Dr. A. Dinakar Reddy2 1Department of Pharmaceutical Analysis, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. 2Professor & Principal, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. A b s t r a c t Analytical methods capable of analyzing huge number of samples in a short time period with ... Read More »
Develop a new, simple, fast, rapid, accurate, efficient and reproducible RP-HPLC method and spectroscopic method for the simultaneous analysis of Azelnidipine and Telmisartan
A. Srikanth*, G. Srikanth1, Shaik afroz begum2, Machiraju Sai Kalyan3 *Associate Professor, Dept. of Pharmaceutical Analysis Vasavi institute of pharmaceutical sciences, Kadapa. 1Assistant Professor, Dept. of Pharmaceutics, Vasavi institute of pharmaceutical sciences, Kadapa. 2Assistant Professor, Dept of Pharmaceutical Chemistry, Vasavi institute of pharmaceutical sciences, Kadapa. 3Student, Department of Pharmaceutical Analysis, Vasavi institute of pharmaceutical sciences, Kadapa. A b s t ... Read More »
Development and Evaluation of Multi-Layer Controlled Release Tablet of Pentoxifylline
K. Sunil Kumar*1, M. Lokesh2 1Associate Professor, Department of Pharmaceutics, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. 2Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India. A b s t r a c t In the present study an attempt was made to prepare Pentoxifylline Extended release tablet for the treatment of ... Read More »
Formulation and In-vitro evaluation of liposomal drug delivery system of metformin HCl
K. Sunil Kumar*1, P. Jeevan Kumar2 1Associate Professor, Department of Pharmaceutics, Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India 2Sun Institute of Pharmaceutical Education and Research, Kakupalli, Nellore, Andhra Pradesh, India A b s t r a c t Metformin is widely used for the treatment of diabetes; the intention of the present study was to ... Read More »
