Tuesday , 7 July 2020

Development and Validation of UV-Spectroscopic Method for Estimation of Formoterol in Bulk and Pharmaceutical Dosage Form

K. Surendra*, P. Penchalamma, G. Vikas, C. Dileep Reddy, S. Chaitanya
Rao’s College of Pharmacy, Chemudugunta, Venkatachalam, Nellore, Andhra Pradesh-524320

A B S T R A C T
The aim of present research work method development and validation for the quantification of Formoterol in bulk and its pharmaceutical dosage form by using UV spectroscopy. The solvent employed for this method was distilled water and absorption maximum was found to be 287nm. The developed method was shown linearity in the range between 5-30µg/ml. The correlation co-efficient was found to be 0.9998. In precision studies the %RSD was found to be ≤ 2. The accuracy was performed by spiking standard drug at 50%, 100% and 150% of the test concentration and the values obtained were within the limit. All the results were satisfactory the developed method was linear, accurate and reproducible.
Keywords: Formoterol, UV Spectroscopy, Distilled water, Assay, Validation.

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