Monday , 21 January 2019

Category Archives: Research in Pharmacology and Toxicology studies

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Review on Glycemic Abnormalities on Coronary Artery Disease

Shaik Salma Sultana*, Sai Kiran Anem 1, Sravani 2Jagan’s college of Pharmacy, Jangala kandriga, SPSR Nellore, Andhra Pradesh, India A B S T R A C Diet has a significant relationship with the risk of coronary heart disease (CHD). Traditionally the effect of diet on CHD was measured with the biomarker for low-density lipoprotein (LDL) cholesterol. However, LDL is not ... Read More »

Porphyriya – The Vampiers Disease

Shaik Salma Sultana*, Sai Kiran Anem1, Shaik Shafi2 Jagan’s College of Pharmacy, Jangala kandriga, SPSR Nellore, Andhra Pradesh, India. A B S T R A C T The  Porphyrias  are a group of seven rare genetic disorders. They are called the porphyrias because they cause accumulation of chemicals called porphyrins (purple-red pigments named from the Greek for purple); or the ... Read More »

Evaluation of Cardioprotective Activity of Ethanolic Extract of Leaves of The Cyanthillium Cinereum Against Isoprenaline Induced Cardiotoxicity In Rats

1Varukolu Soundarya*, 2Chintala Swetha Bindu, 3Dr. Challa Pradeep Kumar, 4Porandla Ravali Department of Pharmacology, Vaageswari College of Pharmacy, Karimnagar, Telangana 505001. A B S T R A C T The present study was aimed at evaluating the hepatoprotective activity of Bauhinia acuminata.L against Carbon tetra chloride induced hepatotoxicity in rats. Hepatic damage was induced by administration of CCL4 (1.5ml/kg b.w, i.p) in combination ... Read More »

Hepatoprotective Activity of Ethanolic Bauhinia Acuminata.L Extract Against Cci4-Induced Liver Damage In Rats

1Porandla Ravali*, 2Dr. Challa Pradeep Kumar, 3Varukolu Soundarya Department of Pharmacology, Vaageswari College of Pharmacy, Karimnagar, India,505001. A B S T R A C T The present study was aimed at evaluating the hepatoprotective activity of Bauhinia acuminata.L against Carbon tetra chloride induced hepatotoxicity in rats. Hepatic damage was induced by administration of CCL4 (1.5ml/kg b.w, i.p) in combination with olive oil ... Read More »

Effect of Induced Hypertension on Bilateral Activity, Task Performance and Spatial Memory In Albino Wistar Rat

1Olorunfemi O.J.*, 2Okosiemiama S.C., 3Okopido I.S, 4Okpe E. Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Choba, Port Harcourt, Nigeria. A B S T R A C T The aim of this study is to evaluate the possible effect of induced hypertension on bilateral activity, task performance and spatial memory. Twenty albino wistar rats ... Read More »

On Demand Delivery of Methotrexate From Self-Assembled Nanoconstructs for Treatment of Rheumatoid Arthritis

Sneha K. Patel, Drashti G. Pathak, Deepa H. Patel* Parul Institute of Pharmacy and Research, P.O.Limda, ta. Waghodia, Vadodara-391760, Gujarat A B S T R A C T The aim of the present investigation was to develop and evaluate on demand delivery of methotrexate from self-assembled nanoconstructs for treatment of rheumatoid arthritis. Methotrexate (MTX)-Dextran sulphate (DS)-Poly lactic co-glycolic acid (PLGA) ... Read More »

Qualitative and Quantitative Identification of Ficus Carica (Anjeer)

Rajesh k Athya*, Shahnaz, Sonam Pal, Sonu Jatav, Rahul Singh, Rahul Raikwar, Mithun Bhowmick, Jagdish Chandra Rathi NRI Institute of Pharmaceutical Sciences, Bhopal, M.P, India A  B  S  T  R  A  C  T Fresh leaves of Figs (Ficus carica), F. Moraceae, were subjected to grind in a electric mixer& extracted it. To assess their effect on the nutritional & Health-Related properties ... Read More »

Evaluation of in-vitro Antitumor Property of Water Weeds (Eichhorniacrassipes and Pistiastratiotes) by MTT Assay

Poonam Sharma1, N. Ganesh*1, Vinoy. K. Shrivastava2 1Department of Research, Jawaharlal Nehru Cancer Hospital & Research Centre, Idgah Hills, Bhopal, Madhya Pradesh 2Department of Biosciences, University Teaching Department, Barkatullah University, Bhopal A B S T R A C T The water weeds Eichhorniacrassipes and Pistiastratiotes were selected to investigate the antitumor property in-vitro by MTT Assay. The IC50 (IC-Inhibitory Concentration) ... Read More »

Behavioral Studies of Agarwood Smoke in Rats

Abdulmalik AbuAbah, Rabbani SI*, Sultan Sajid Department of Pharmacology, College of Pharmacy, Qassim University, Saudi Arabia A  B  S  T  R A C T In this study the effects of agarwood smoke exposure was evaluated on the general, CNS and reproductive behaviors in male and female rats. The behavioral studies were conducted on both male and female rats by exposing ... Read More »

Combined effect of Coenzyme Q10, Riboflavin, Niacin, Selenium (CoRNS) and Emblicaofficinalis studied on experimental atherosclerosis in rats

U. Indumathi1*, T.P. Sachdanandam2 1Department of Biochemistry, T.S.Narayanaswami College of Arts and Science, University of Madras, Chennai-600130. 2Department of Pathology, Dr. ALM. PGIBMS, Taramani, Chennai-600113. A  B  S  T  R A C T Cardiovascular diseases are becoming more prevalent in the world.  Atherosclerosisis one of the most widespread and leading diseases which causes death in most developed countries. The present ... Read More »

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