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Category Archives: Research in Pharmacology and Toxicology studies

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Pharmacological Evaluation of Cynodon Dactylon Plant Extracts for Cardioprotective Activity

Kalangi Deepikanjali, P. Naresh Babu* Department of pharmacology, Ratnam Institute of Pharmacy, Pidathapolur  (V&P), Muthukur (M), SPSR Nellore (Dist) 524346, Andhra Pradesh, India. A B S T R A C T The Plant Cynodon dactylon Family (Graminae/Poaceae) is extensively used in clinical practice but it has various pharmacological activities have been reported. It is a very familiar plant almost available ... Read More »

Evaluation of Anti-Hyperlipidemic Activity of Methanolic Extract of Sesbania Grandiflora in Wistar rats and Observation on Heart rate and Body weight

Dr. Gampa Vijay Kumar*1, Mr. Murali Sollu2, Ama Sneha Sai3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T Major complication of ... Read More »

A  Review on Antibiotics and the Liver a Love-Hate Relationshp

Shaik. Salma sultana, Kinnera Sasi kumar Jagan’s College of Pharmacy, Jangala kandriga, SPSR Nellore, Andhra Pradesh, India. ABSTRACT Antibiotic therapy is often an essential part of the management of hepatobiliary disease, and yet can cause significant hepatic morbidity and mortality. This review article examines the epidemiology and pathogenesis of antibiotic induced liver injury, and discusses the role of antibiotics in ... Read More »

Fibrodysplasia Ossificans Progressiva an ACVR1 Gene Mutation

Mocharlla Mallikarjuna Dept. of Pharmacology, Saastra College of Pharmaceutical Education and Research, Nellore, A.P, India ABSTRACT It is a rarest and most severe genetic disabling disease which may effect on the muscles and leads to irreversible muscle to bone termination, which may cause a worse body shape of human body. This disorder was affects 1 out of 2000000 people, around ... Read More »

Pharmacological Screening of Antihypertensive Properties of Chloroform Extracts of Trichopus Zelanicus Using In vivo Models

Dr. Gampa Vijay Kumar1*, Mr. Murali.Sollu2, M. Vivek vardhan3 1Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. 2,3KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India. A B S T R A C T Hypertension is a chronic disorder characterized by a persistently elevated blood pressure exceeding 140/90 mmHg ... Read More »

Review on Glycemic Abnormalities on Coronary Artery Disease

Shaik Salma Sultana*, Sai Kiran Anem 1, Sravani 2Jagan’s college of Pharmacy, Jangala kandriga, SPSR Nellore, Andhra Pradesh, India A B S T R A C Diet has a significant relationship with the risk of coronary heart disease (CHD). Traditionally the effect of diet on CHD was measured with the biomarker for low-density lipoprotein (LDL) cholesterol. However, LDL is not ... Read More »

Porphyriya – The Vampiers Disease

Shaik Salma Sultana*, Sai Kiran Anem1, Shaik Shafi2 Jagan’s College of Pharmacy, Jangala kandriga, SPSR Nellore, Andhra Pradesh, India. A B S T R A C T The  Porphyrias  are a group of seven rare genetic disorders. They are called the porphyrias because they cause accumulation of chemicals called porphyrins (purple-red pigments named from the Greek for purple); or the ... Read More »

Evaluation of Cardioprotective Activity of Ethanolic Extract of Leaves of The Cyanthillium Cinereum Against Isoprenaline Induced Cardiotoxicity In Rats

1Varukolu Soundarya*, 2Chintala Swetha Bindu, 3Dr. Challa Pradeep Kumar, 4Porandla Ravali Department of Pharmacology, Vaageswari College of Pharmacy, Karimnagar, Telangana 505001. A B S T R A C T The present study was aimed at evaluating the hepatoprotective activity of Bauhinia acuminata.L against Carbon tetra chloride induced hepatotoxicity in rats. Hepatic damage was induced by administration of CCL4 (1.5ml/kg b.w, i.p) in combination ... Read More »

Hepatoprotective Activity of Ethanolic Bauhinia Acuminata.L Extract Against Cci4-Induced Liver Damage In Rats

1Porandla Ravali*, 2Dr. Challa Pradeep Kumar, 3Varukolu Soundarya Department of Pharmacology, Vaageswari College of Pharmacy, Karimnagar, India,505001. A B S T R A C T The present study was aimed at evaluating the hepatoprotective activity of Bauhinia acuminata.L against Carbon tetra chloride induced hepatotoxicity in rats. Hepatic damage was induced by administration of CCL4 (1.5ml/kg b.w, i.p) in combination with olive oil ... Read More »

Effect of Induced Hypertension on Bilateral Activity, Task Performance and Spatial Memory In Albino Wistar Rat

1Olorunfemi O.J.*, 2Okosiemiama S.C., 3Okopido I.S, 4Okpe E. Department of Human Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Port Harcourt, Choba, Port Harcourt, Nigeria. A B S T R A C T The aim of this study is to evaluate the possible effect of induced hypertension on bilateral activity, task performance and spatial memory. Twenty albino wistar rats ... Read More »

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