Friday , 10 April 2020

Investigation for Antidiabetic Activity of Ethanolic Bark Extracts of Viburnum Opulus

T. Prashanth Kumar1, Dr. Nagaraju, M.Kulkarni2, Dr. Vijaya Kumar Gampa3
1KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
2Asso. Professor, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.
3Professor and Head, Dept. of Pharmacy, KGR Institute of Technology and Management, Rampally, Kesara, Rangareddy, Telangana, India.

A B S T R A C T
In the presant work an attempt has been made to investigate the anti-diabetic activity of the ethanolic extracts of the plant viburnum opulus, The results concluded that EEVO (500 mg/kg) have definite antidiabetic activity in Streptozocin induced Diabetic model and which is equipotent activity when compared with Atorvastatin treated groups. Further studies on this extract may lead to identify the possible mechanism of action and isolation of active principle from the same. EEVO have different medicinal properties and may able to treat diabetes & diabetics complications. Subjected to acute oral toxicity studies and found that the EEVO is safe to use up to the dose of 1000mg/kg. The EEVO was found to be in dose dependent way against alloxan-induced diabetes in rats. The reduction of the elevated blood glucose levels in diabetic rats on treatment with the extract at two different concentrations confirmed that ethanolic extract of EEV Oposses Antidiabetic activity & has shown significant effect when compared to Streptozocin administration.
Keywords: viburnum opulus, Antidiabetic activity

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