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Tag Archives: levofloxacin

HPLC Estimation of Levofloxacin in Bulk and Pharmaceutical Formulations

Rajkiran Kolakota*, Y. Rupavathi Department of Pharmaceutical Analysis, Sri Sivani College of Pharmacy, NH-16, Chilakapalem Jn, Srikakulam-532402, A.P ABSTRACT A HPLC method was developed and validated to determine trace amounts of levofloxacin related substances & degradation products in its formulation. Separation of levofloxacin from impurity A, impurity B, impurity C and unknown degradation products was achieved on a YMC-Pack Pro ... Read More »

In-Silico Structure-Activity Relationship and Molecular Docking Study of Levofloxacin and its Mono substitted Analogues against the Escherichia coli DNA Gyrase

O.A Durojaye*, U. I Njoku, S. Cosmas, E. N Akpan, M. M Ganyam University of Nigeria, Nsukka.  A B S T R A C T Background: Escherichia coli is one of the most frequent causes of many common bacterial infections, including cholecystitis, bacteremia, cholangitis, urinary tract infection (UTI), traveler’s diarrhea, and other clinical infections such as neonatal meningitis and pneumonia. ... Read More »

Formulation and In Vitro Evaluation of Oral Floating Tablets of Levofloxacin Hydrophilic Matrix

1Mohan kumar Atluri*1, K. Saravan kumar1, Jagadesh kumar Yadav kalluri1, P. Sravan kumar2, Yagagowri1, P. Sravanthi3 Department pharmaceutics, Sree Vidyanikethan College Pharmacy, A. Rangampet, Tirupati, A.P, India-517102. 2Department pharmaceutics, Krishna Teja College of Pharmacy, Tirupati, A.P, India-517102. 3Department pharmaceutics, JNTUA OTRI, Anantapure, A.P, India Received: 15 June2014, Accepted: 19 July 2014, Published Online: 10 August 2014 Abstract The present study was ... Read More »

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