Photo stability indicating UV visible spectrophotometric method for tezepelumab development and validation

Ajay Kumar Ch*,Bharghava Bhushan Rao P¹,Jhansi M², Jyothi D³, Narasimha Rao K⁴, Murali krishna M⁵, Narsu kumari⁶

*²³⁴⁵⁶A.M.Reddy Memorial College of Pharmacy, Narasaraopet, 522412, A.P, India
¹V V Institute of Pharmaceutical Sciences, Gudlavalleru, A.P, India

A  B  S  T  R A C T
Spectroscopy is the study of how electromagnetic radiation interacts with matter. Electromagnetic radiation is frequently released as matter relaxes back to its initial (ground) state after being energised (stimulated) by the application of thermal, electrical, nuclear, or radiant energy. The purpose of this research with the results of this work, we verify a stability-indicating UV approach for the measurement of tezepelumab in bulk and pharmaceutical formulations. The determination of the Tezepelumab dosage form was a good fit for the proposed UV-Spectrophotometric approaches. Every parameter of the created methods complied with the requirements of the ICH standards for method validation. It is claimed that the developed UV methods for the estimate of tezepelumab are quick, easy to use, precise, accurate, sensitive, affordable, and repeatable within the defined method parameter.
Keywords: Spectroscopy, electromagnetic radiation, Tezepelumab, ICH.