Thursday , 2 May 2024

Synthesis and Characterization of 2-[1H-benzimidazole-2yl-sulfanyl]-N-[(E)-(3-methylphenyl) methylidene] acetohydrazide

About author Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Many important biochemical compounds and drugs of natural origin contain heterocyclic ring structures. Among these e.g. Carbohydrates, essential amino acids, vitamins, alkaloids, glycosides etc. the presence of heterocyclic structures in such diverse types of compounds is strongly indicative of the diverse types of the pharmacological activity. ... Read More »

ANTI-INFLAMMATORY ACTIVITY OF 3-[(5-SUBSTITUED)-1, 3, 4 OXADIAZOLE-2-YL) METHYL AMINO]-2-METHYL QUINAZOLIN-4(3H)-ONES

 About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: The process of establishing a new drug is exceedingly complexioned involves the talents of people from a variety of disciplines including Pharmaceutical chemistry, biochemistry, physiology, pharmacology, pharmaceutics and medicine. Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the ... Read More »

ANALGESIC ACTIVITY OF 3-[(5-SUBSTITUED) – 1, 3, 4 OXADIAZOLE-2-YL) METHYL AMINO]-2-METHYL QUINAZOLIN-4(3H)-ONES

About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT:  Heterocyclic drug having wide spectrum of activity, Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, antihistaminic, anticancer and so on. All the synthesized quinazolinone derivatives were confirmed preliminarily by M.P and TLC ... Read More »

Synthesis and Characterization of 2-[1H- benzimidazole-2yl-sulfanyl]-N-[(E)-(4-methoxy phenyl) methylidene] Aceto hydrazide

About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India *E-mail: [email protected] Content : The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Diversity of biological response profile has attracted considerable interest of several researchers across the globe to explore thisskeleton for its assorted therapeutic significance. 1.Synthesis ... Read More »

ANTIMICROBIAL SCREENING OF SOME NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES

About Author Ramesh Dhani  Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India. *E-mail: [email protected] ABSTRACT: Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, heterocyclic structures form the basis of many pharmaceutical, agrochemical and veterinary products. The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Diversity of ... Read More »

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