Friday , 17 May 2024

Synthesis and Characterization of 4-(2-Chlorobenzylidene)-1-{4-[3-(substituted phenyl)prop-2-enoyl]phenyl}-2-phenyl-imidazol-5-one

About author : Amee B. Patel & Pankaj S. Patel* Department of Chemistry, Sheth L.H. Science College, Mansa, India. Scholar of J.J.T. University, Jhunjhunu, Rajasthan. E-mail: [email protected] Abstract : 4-(2-Chlorobenzylidene)-1-{4-[3-(substituted phenyl)prop-2-enoyl]phenyl}-2-phenyl-imidazol-5-one synthesized by the condensation of 1-(4-acetylphenyl)-4-(2-chlorobenzylidene)-2-phenyl-imidazol-5-one with various aldehydes in presence of ethanol. The intermediate 1-(4-acetylphenyl)-4-(2-chlorobenzylidene)-2-phenyl-imidazol-5-one synthesized by the condensation of  4-(2-chlorobenzylidene)-2-phenyl-1,3-oxazol-5-one  with 1-(4-aminophenyl) ethanone in presence of pyridine. ... Read More »

Synthesis and Characterization of 4-[2′-(5′-Nitro) Imidazolyl] Benzoyl (N-Me) Leucine

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: In the past two decades, a wide variety of bioactive peptides have been discovered. Many of the heterocyclic found to exhibit antifungal, antibacterial, cytotoxic, antineoplastic, insecticidal, anti-inflammatory, tyrosinase inhibitory and melanin production inhibitory activities. Imidazole has been drawn as promising structural units in the ... Read More »

Synthesis and characterization of 3-[(5-phenyl hydroxyl-1, 3, 4-oxadiazol-2-yl) methyl amino]-2-methyl quinazolin-4(3h)-one

About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Quinazolinone is a heterocyclic compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, ... Read More »

A REVIEW ON MANAGEMENT AND SCOPE OF MEDICAL TOURISM IN INDIA

About author : Patel Harnish K, Patel Priyanka R. Editor, IJPRBS, India E-mail: [email protected]   Abstract: India is a good location to receive medical treatments and considered a leader in promoting medical tourism. Healthcare, like food and shelter, is a basic need of Humanity. Given the potential India holds as a healthcare destination, the healthcare tourism sector can be a ... Read More »

SYNTHESIS AND CHARACTERIZATION OF 4-[2′-(5′-NITRO) IMIDAZOLYL] BENZOYL (N-ME) VALINE

About author : Ramesh Dhani Dept of  Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail : [email protected] ABSTRACT: Many of the heterocyclic found to exhibit antifungal, antibacterial, cytotoxic, antineoplastic, insecticidal, anti-inflammatory, tyrosinase inhibitory and melanin production inhibitory activities. Imidazole has been drawn as promising structural units in the field of medicinal chemistry. Introduction of D-amino acids and N-methylation of amino acids like ... Read More »

SYNTHESIS AND CHARACTERIZATION OF 4-[2′-(5′-NITRO) IMIDAZOLYL] BENZOYL (N-ME) TYROSINE

About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Introduction of D-amino acids and N-methylation of amino acids like tyrosine, valine, alanine etc enhanced antimicrobial activity. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent biological activities. Many of the ... Read More »

Beginning Perl for Bioinformatics

Beginning Perl for Bioinformatics James Tisdall Publisher: O’Reilly This book shows biologists with little or no programming experience how to use Perl, the ideal language for biological data analysis. Each chapter focuses on solving particular problems or class of problems, so you’ll finish the book with a solid understanding of Perl basics, a collection of programs for such tasks as ... Read More »

Method Validation in Pharmaceutical Analysis

Method Validation in Pharmaceutical Analysis J. Ermer and J. H. McB. Miller Methods used in pharmaceutical analysis must be sufficiently accurate, specific, sensitive and precise to conform to the regulatory requirements as set out in the relevant guidelines of “The International Conference of Technical Requirements for the Registration of Pharmaceutical for Human Use ” (ICH), which are applied by the ... Read More »

The Organic Chemistry of Drug Synthesis

The Organic Chemistry of Drug Synthesis DANIEL LEDNICER LESTER A. MITSCHER The reception accorded “Organic Chemistry of Drug Synthesis11 seems to us to indicate widespread interest in the organic chemistry involved in the search for new pharmaceutical agents. We are only too aware of the fact that the book deals with a limited segment of the field; the earlier volume ... Read More »

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