Isolation and Characterization of 4’, 5, 7,-trihydroxy isoflavone from Crinum defixum Ker-Gawler plant leaves and their Biological activities

A. Elaiyaraja*1, G.Chandramohan2
1Department of Chemistry, A.V.V.M. Sri Pushpam College, Poondi, Thanjavur-613 503, Tamilnadu, India.
2Department of Chemistry, Jairams Arts and Science College, Karur-3, Tamilnadu, India.

A B S T R A C T
The present study was carried out to isolation and characterization of Flavone compounds present in the Crinum defixum Ker-Gawler leaves, which is an important medicinal plant. Worldwide trends towards the utilization of natural plant remedies have created an enormous need for the use of medicinal plants. Different pharmacological properties of C.defixum Ker-Gawler have already been reported. The plant was extracted for various solvents in increasing order of polarity from using n-hexane, chloroform, ethyl acetate, acetone, ethanol, butanol and methanol. Thus, the present study was performed to investigate the preliminary phytochemical screening, isolation and characterization of flavone compounds present in the C.defixum Ker-Gawler leaves using FT-IR, GC-MS, NMR and MASS Spectral techniques and their biological activities.
Keywords: Crinum defixum Ker-Gawler, Phytochemical screening, Isolation, Characterization, FT-IR, GC-MS, NMR, MASS Spectra, 4′, 5, 7-Trihydroxy isoflavone.