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About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur,India ABSTRACT: Quinazoline is a bicyclic compound earlier known as benzo-1, 3-diazine. The name quinazolinone (German: Chinazolin) was proposed for its compound by wedding, on observing that this was isomeric with the then compound crinoline and quinaoxaline. The numbering of the quinazoline ring system which is currently used was suggested ... Read More »
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BENZOXAZOLE: THE MOLECULE OF DIVERSE PHARMACOLOGICAL ACTIVITIES
About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Oxazole is a heterocyclic organic compound that has a five-member ring molecular structure, containing oxygen, nitrogen as heteroatoms at its 1, 3-positions. Benzoxazoles are derivatives of oxazoles. Benzoxazoles is a planar molecule with conjugated p electrons sextets in the cyclic systems. The lone pair of ... Read More »
A COMPREHENSIVE REVIEW ON SUBSTITUTED QUINAZOLINONES AND ITS DERIVATIVES
About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Quinazolinones and several of their derivatives have been found to be of greater interest in view of their varied biological and pharmacological properties. The ... Read More »
SYNTHESIS AND CHARACTERIZATION OF ETHYL (1H-BENZIMIDAZOL-2-YL- SULFANYL) ACETATE
About author: Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, anantapur, India E-mail: [email protected] ABSTRACT: The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Recently in benzimidazole chemistry has been revived somewhat by the discovery that the 5, 6-dimethyl benzimidazole moiety is a part of the chemical structure of vitamin B12. Diversity ... Read More »
EXTRACTION AND CHEMICAL INVESTIGATION OF LEAVES OF PTEROSPERMUM ACERIFOLIUM
About author: Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Herbal Medicine can be broadly classified into various basic systems: Traditional Chinese Herbalism, which is part of Traditional Oriental Medicine, Ayurvedic Herbalism, which is derived from Western Herbalism, which originally came from Greece and Rome to Europe and then spread to North and South America. Indian ... Read More »
Synthesis and Characterization of 2-[1H-benzimidazole-2yl-sulfanyl]-N-[(E)-(3-methylphenyl) methylidene] acetohydrazide
About author Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Many important biochemical compounds and drugs of natural origin contain heterocyclic ring structures. Among these e.g. Carbohydrates, essential amino acids, vitamins, alkaloids, glycosides etc. the presence of heterocyclic structures in such diverse types of compounds is strongly indicative of the diverse types of the pharmacological activity. ... Read More »
ANTI-INFLAMMATORY ACTIVITY OF 3-[(5-SUBSTITUED)-1, 3, 4 OXADIAZOLE-2-YL) METHYL AMINO]-2-METHYL QUINAZOLIN-4(3H)-ONES
About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: The process of establishing a new drug is exceedingly complexioned involves the talents of people from a variety of disciplines including Pharmaceutical chemistry, biochemistry, physiology, pharmacology, pharmaceutics and medicine. Quinazolinone is a heterocyclic chemical compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the ... Read More »
ANALGESIC ACTIVITY OF 3-[(5-SUBSTITUED) – 1, 3, 4 OXADIAZOLE-2-YL) METHYL AMINO]-2-METHYL QUINAZOLIN-4(3H)-ONES
About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Heterocyclic drug having wide spectrum of activity, Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, antihistaminic, anticancer and so on. All the synthesized quinazolinone derivatives were confirmed preliminarily by M.P and TLC ... Read More »
Synthesis and Characterization of 2-[1H- benzimidazole-2yl-sulfanyl]-N-[(E)-(4-methoxy phenyl) methylidene] Aceto hydrazide
About author : Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India *E-mail: [email protected] Content : The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Diversity of biological response profile has attracted considerable interest of several researchers across the globe to explore thisskeleton for its assorted therapeutic significance. 1.Synthesis ... Read More »
ANTIMICROBIAL SCREENING OF SOME NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES
About Author Ramesh Dhani Department of Pharmaceutical Chemistry JNTUA-OTRI, Anantapur, India. *E-mail: [email protected] ABSTRACT: Heterocyclic chemistry comprises at least half of all organic chemistry research worldwide. In particular, heterocyclic structures form the basis of many pharmaceutical, agrochemical and veterinary products. The benzimidazole contains a phenyl ring fused to an imidazole ring, as indicated in the structure of benzimidazole. Diversity of ... Read More »
