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What is Biochemistry Each part of every living being is biochemically connected. Biochemistry is at the heart of life science. It is a fascinating, diverse and sprawling discipline; which makes it near impossible to pigeon-hole or define concisely. Many look upon biochemistry as a science that underpins and explains the essential processes of life, impacting on: Biotechnology and bioinformatics, Cell biology ... Read More »
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Carbohydrates Analysis
Carbohydrates Analysis Dr. Munaf S. Daoud Aldehyde or Ketone derivatives of the higher polyhydric alcohols or compounds which yield these derivatives on hydrolysis. Monosaccharides: Can be classified as trioses, tetroses, pentoses, hexoses and heptoses depending upon the number of carbon atoms, and as aldoses or ketoses, depending upon whether they have an aldehyde or ketone group. Mutarotation: The changes of ... Read More »
MEDICINAL CHEMISTRY OF BIOACTIVE NATURAL PRODUCTS
Medicinal Chemistry of Bio-active Natural Products XIAO-TIAN LIANG WEI-SHUO FANG Medicinal chemistry has evolved from the chemistry of bioactive compounds in early days to works at the interface of chemistry and biology nowadays. Medicinal Chemistry of bioactive natural products spans a wide range of fields, including isolation and characterization of bioactive compounds from natural sources, structure modification for optimization of their activity ... Read More »
OVERVIEW ON FAST DISSOLVING ORAL FILMS
About author : Dr. N. G. Raghavendra Rao Principal and Professor Jyothishmathi Institute of Pharmaceutical Science Ramakrishna Colony, Thimmapur, KARIMNAGAR-505481, Andhra Pradesh Email: [email protected] ABSTRACT: Fast-dissolving oral delivery systems are solid dosage forms, which disintegrate or dissolve within 1 min when placed in the mouth without drinking water or chewing. More recently, fast-dissolving films are gaining interest as an alternative ... Read More »
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL SCREENING OF SOME NOVEL BENZOIN DERIVATIVES
About author: P. Deepthi Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur,India E-mail: [email protected] INTRODUCTION :A natural product is a chemical compound or substance produced by a living organism – found in nature that usually has a pharmacological or biological activity for use in pharmaceutical drug discovery, drug design. A natural product can be considered as such even if it ... Read More »
Synthesis and Reactivity of Some Novel Quinazoline Derivatives
About author : Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, India E-mail: [email protected] ABSTRACT Quinazoline is a bicyclic compound earlier known as benzo- 1, 3-diazine. The name quinazolinone (German: Chinazolin) was proposed for its compound by Weddige, on observing that this was isomeric with the then compound cinnoline and quinaoxaline. The numbering of the quinazoline ring system which is currently ... Read More »
Synthesis and Characterization of 4-[2′-(5′-Nitro) Imidazolyl] Benzoyl(N-Me) Threonine
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA-OTRI, India E-mail: [email protected] ABSTRACT: Introduction of D-amino acids and N-methylation of amino acids like tyrosine, valine, alanine etc enhanced antimicrobial activity. Condensation of heterocyclic moieties viz nicotinic acid, thiazole, coumarin, quinoline, furan, imidazole etc. with amino acids and peptides resulted in compounds with potent biological activities. Many of the heterocyclic found ... Read More »
Synthesis and Characterization of 4-(2-Chlorobenzylidene)-1-{4-[3-(substituted phenyl)prop-2-enoyl]phenyl}-2-phenyl-imidazol-5-one
About author : Amee B. Patel & Pankaj S. Patel* Department of Chemistry, Sheth L.H. Science College, Mansa, India. Scholar of J.J.T. University, Jhunjhunu, Rajasthan. E-mail: [email protected] Abstract : 4-(2-Chlorobenzylidene)-1-{4-[3-(substituted phenyl)prop-2-enoyl]phenyl}-2-phenyl-imidazol-5-one synthesized by the condensation of 1-(4-acetylphenyl)-4-(2-chlorobenzylidene)-2-phenyl-imidazol-5-one with various aldehydes in presence of ethanol. The intermediate 1-(4-acetylphenyl)-4-(2-chlorobenzylidene)-2-phenyl-imidazol-5-one synthesized by the condensation of 4-(2-chlorobenzylidene)-2-phenyl-1,3-oxazol-5-one with 1-(4-aminophenyl) ethanone in presence of pyridine. ... Read More »
Synthesis and Characterization of 4-[2′-(5′-Nitro) Imidazolyl] Benzoyl (N-Me) Leucine
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: In the past two decades, a wide variety of bioactive peptides have been discovered. Many of the heterocyclic found to exhibit antifungal, antibacterial, cytotoxic, antineoplastic, insecticidal, anti-inflammatory, tyrosinase inhibitory and melanin production inhibitory activities. Imidazole has been drawn as promising structural units in the ... Read More »
Synthesis and characterization of 3-[(5-phenyl hydroxyl-1, 3, 4-oxadiazol-2-yl) methyl amino]-2-methyl quinazolin-4(3h)-one
About author: Ramesh Dhani Dept. of Pharmaceutical Chemistry JNTUA – OTRI, Anantapur, India E-mail: [email protected] ABSTRACT: Quinazolinone is a heterocyclic compound. There are two structural isomers, 2-quinazolinone and 4-quinazolinone, with the 4-isomer being the more common. Various novel classes of structurally different quinazolinones have been designed and synthesized depicting potential interventions such as antibacterial, antifungal, antiviral, anticonvulsant, CNS depressant, anti-inflammatory, ... Read More »
