Sunday , 20 May 2018

Tag Archives: HPMC

Formulation and Evaluation of Atenolol floating Drug Delivery Systems

Tharun D*, N. Devanna, Thirumalesh Naik SB, Siva Kumari K, Hindustan Abdul Ahad, Maddileti R Jawaharlal Nehru Technological University Ananthapur, Oil Technological and Pharmaceutical Research Institute, Ananthapuramu, Andhra Pradesh, India -515001 ABSTRACT Gastro retentive drug delivery is apracticeto extend stomach retaining and aiming stomach site for local or systemic effects. Atenolol is a cardio selective β1 blocker used in the ... Read More »

Design and In-Vitro Characterization of Cyclobenzaprine Floating Microspheres

D. Keerthi Raj*, B. Ramya Sree, S. Anusha, T. Anil Goud Assistant Professor, Department of Pharmaceutics, Vijay College of Pharmacy, Nizamabad, Telangana, India Abstract In the present work, floating microspheres of Cyclobenzaprine using sodium bicarbonate, HPMCK100M, HPMCK15M, HPMC K4M as copolymers were formulated to deliver Cyclobenzaprine via oral route. The results of this investigation indicate that ionic cross linking technique ... Read More »

Fabrication and evaluation of acyclovir Transdermal patches by using different polymer compositionps: In-Vitro

R. Venu Priya*1 and Vinesh Kumar2 1Research Scholar, Sun Rise University, Alwar, Rajasthan, India. 2Department of Pharmacy, Sun Rise University, Alwar, Rajasthan, India. A B S T R A C T Transdermal drug delivery systems are becoming more popular in the field of modern pharmaceutics. Different matrix-type transdermal films containing acyclovir was formulated with an objective to study the effect ... Read More »

Formulation and Evaluation of Non-Efervescent Floating Tabelts of Famotidine HCl

Heeralal*, P. Shashikala Department of Pharmacy, University College of Technology, Osmania University, Hyderabad, India. Abstract The objective of the present investigation was to prepare gastro retentive drug delivery systems of Famotodine floating tablets. Famotidine binds competitively to H2-receptors located on the basolateral membrane of the parietal cell, blocking histamine affects. This competitive inhibition results in reduced basal and nocturnal gastric ... Read More »

Formulation and Evaluation of Bilayer Floating Tablet Containing Verapamil Hydrochloride

Shivendra Pratap Singh*, Navneet Kumar Verma, Abhay Pratap Singh, Reena Singh Department of Pharmacy, Kailash Institute of Pharmacy and Management, GIDA, Gorakhpur, U.P. India-273209 A B S T R A C T The objective of the present work was to develop a bilayer-floating tablet for Verapamil HCl using direct compression technology using polymers such as HPMC K100 and Carbopol 940. ... Read More »

Formulation and In-vitro Evaluation of Pantoprazole Sodium Delayed Release Tablets

A. Gowramma1*, M. Ramu2, P. Mounika3 1Dept. of Pharmaceutics, Sri Padmavathi School of Pharmacy, Tiruchanoor, Tirupati, A.P, India 2Dept. of Pharmaceutics, Santhi ram college of pharmacy, Nandyal, Kurnool, A.P, India 3Dept of Pharmaceutical Analysis, Sree Vidyanikethan College of Pharmacy, Rangampet, Tirupati, A.P, India A B S T R A C T Pantoprazole is a category of proton pump inhibitor, belongs ... Read More »

Formulation and Evaluation of Simvastatin Effervescent Floating Tablets

B. Venkateswara Reddy1*, M.Sekar2  1Department of Pharmaceutics, Santhiram College of Pharmacy, Nandyal, Kurnool-518501 2Department of Pharmaceutical Chemistry, Santhiram College of Pharmacy, Nandyal, Kurnool-518501 A B S T R A C T In the present research work gastro retentive floating matrix formulation of Simvastatin were prepared by using various hydrophilic polymers. Gas generating agent sodium bicarbonate concentration was optimized. Then formulations ... Read More »

Design and Characterization of Chronotherapeutic Drug Delivery System of Dexibuprofen for the Treatment of Arthritis

Kishor*1, Bindu Madhavi2, K. Someshwar2 1Department of Pharmceutics, St. Pauls College of Pharmacy, Hyderabad, Telangana, India 2Manager, Formulation R&D, KP Labs (A Division of KDPL), Kothapet, Hyderabad Telangana, India A B S T R A C T In the present research work, chronotherapeutic drug delivery of Dexibuprofen was carried out. Chronotherapeutics refers to a treatment method in which in-vivo drug ... Read More »

Formolation and Evaluation of Fast Dissolving Sublingual Films

Makwana Rajeshree*1, Patel Harsha2, Patel Vishnu 3 1Department of Pharmaceutics, R.H. Patel College of Pharmacy, Dahemi-388 560, Gujarat, India. 2Department of Pharmaceutical Technology, Indukaka Ipcowala College of Pharmacy, New V.V. Nagar- 388 121, Gujarat, India. 3Department of Pharmaceutics, R.C. A.R. College of pharmacy and gathel institute of pharmacy, V.V.Nagar-388120, Gujarat, India. A B S T R A C T The fast ... Read More »

Development of Stomach Specific Floating Oral Insitu Gel of Domperidone for Children

M. Nirosha*1, S. Mumtaz Begum2, B. Hari Krishna2, V. Manideep2, G. Soujanya2, G. Venkatesh2 1Department of Pharmaceutics, OTRI, JNTUA, Ananthapuramu, A.P, India. 2Department of Pharmaceutics, SKUCOPS, SK University, Ananthapuramu, A.P, India. A B S T R A C T Domperidone, is an antiemetic drug, has been used as an add-on treatment in adults and children. To reduce the dosing frequency ... Read More »

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