Friday , 15 December 2017

Formulation and In-vitro Evaluation of Tolvaptan Oraldispersible Tablets

Amareshwar Shabada1, Yellanki Prashanthi2
1Assistant Professor, Department of Pharmaceutics, St. Mary’s Pharmacy College, Deshmukhi,
Pochampally, Yadadri, Telangana-508284
2Assistant Professor, Department of Pharmaceutical Analysis and Quality Assurance, Nizam Institute of Pharmacy, Deshmukhi, Pochampally, Yadadri, Telangana-508284

In the present work, an attempt has been made to develop oral dispersible tablets of Tolvaptan. “Among all the formulations F2” formulation showed maximum % drug release i.e., 97.26 % in 45 min hence it is considered as optimized formulation. The F2 formulation contains SSG as super disintegrate in the concentration of 15mg.
Keywords: Tolvaptan, oral dispersible tablets

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